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blood serum; body mass index; calcium; diabetes; femur; medical records; men; osteoporosis; retrospective studies; risk; vitamin D; women; China
Abstract:
... To investigate the relationship between serum 25-hydroxyvitamin D (25(OH)D) and risk of incident diabetes in Hong Kong Chinese, after accounting for the effect of multiple bone- and mineral-related markers. We conducted a retrospective study on the Hong Kong Osteoporosis Study cohort. Incident diabetes was ascertained using electronic medical records. Serum 25(OH)D was measured at baseline and its ...
María Insenser; Samuel Moncayo; M. Ángeles Martínez‐García; Elena Fernández‐Durán; Sara Samino; Francisco Álvarez‐Blasco; Manuel Luque‐Ramírez; Héctor F. Escobar‐Morreale
androgens; animal ovaries; blood sampling; body mass index; fat intake; females; glucose; high density lipoprotein; ingestion; low density lipoprotein; men; metabolic diseases; nuclear magnetic resonance spectroscopy; obesity; particle size; pathogenesis; patients; polycystic ovary syndrome; very low density lipoprotein; women
Abstract:
... SCOPE: Postprandial dysmetabolism plays a major role in the pathogenesis of metabolic disorders such as obesity and the polycystic ovary syndrome (PCOS). The aim is to characterize the circulating lipoprotein particle profiles in response to oral glucose, lipid, and protein challenges. METHODS AND RESULTS: 17 women with PCOS, 17 control women, and 19 healthy men selected to have similar age and bo ...
adults; animal-based foods; blood lipids; body mass index; environmental sustainability; longitudinal studies; men; models; plant-based diet; plant-based foods; regression analysis; women
Abstract:
... AIM: Plant‐based diets are recommended in the context of environmental sustainability and health. Since not all plant foods can be considered beneficial, a distinction needs to be made between healthful and unhealthful plant foods. The aim of this study was to investigate longitudinal associations between changes in an overall plant‐based diet index, a healthful plant‐based diet index and an unhea ...
... A 12-week-long randomized, double-blind, placebo-controlled, parallel-group comparison trial was conducted to determine the effects of long-term standardized bilberry extract (SBE) intake on tonic accommodation of ciliary muscle caused by visual display terminal (VDT) tasks. This study was compliant with the accordance with CONSORT 2010 statement. A total of 109 healthy adult men and women aged 20 ...
... The aim was to assess the gut microbiota of long-livers from Moscow. This study included two groups of patients who signed their consent to participate. The group of long-livers (LL) included 20 participants aged 97–100 years (4 men and 16 women). The second group included 22 participants aged 60–76 years (6 men) without clinical manifestations of chronic diseases (healthy elderly). Gut microbiota ...
... We determined the effects of time-restricted feeding (TRF; 8 h/d) versus extended feeding (EXF; 15 h/d) on 24-h and postprandial metabolism and subjective opinions of TRF in men with overweight/obesity. In a randomized crossover design, 11 sedentary males (age 38 ± 5 y; BMI: 32.2 ± 2.0 kg/m²) completed two isoenergetic diet protocols for 5 days, consuming meals at 1000, 1300 and 1700 h (TRF) or 07 ...
... Importance. Obesity is a worsening epidemic worldwide. Effective and accessible weight loss programs to combat obesity on a large scale are warranted, but a need for frequent face-to-face care might impose a limitation. Objective. To evaluate whether individuals following a weight loss program based on a mobile application, wireless scale, and nutritional program but no face-to-face care can achie ...
athletic performance; blood lipids; chickpeas; cholesterol; cross-over studies; dietary fiber; females; games; global positioning systems; high density lipoprotein; high fiber foods; lentils; lipid composition; men; nutrients; peas; sports; women
Abstract:
... Pulses (i.e., lentils, chickpeas, beans, peas) are low-glycemic index, high-fiber foods that are beneficial for improving blood lipids. Young soccer players typically have low dietary fiber intake, perhaps because of concerns regarding gastro-intestinal problems during exercise performance. Twenty-seven (17 females) soccer players were randomized to receive a pulse-based diet or their regular diet ...
Mediterranean diet; bioelectrical impedance; bone density; food records; hips; incidence; lean body mass; men; muscles; nutrients; prospective studies; research; ultrasonics; women
Abstract:
... Research on Mediterranean diet (MD) adherence and musculoskeletal health is limited. The current study determined if adherence to the alternative MD score (aMED) and MD score (MDS), quantified from 7-d food diaries, was associated with fracture incidence, bone density (calcaneal broadband ultrasound attenuation (BUA)) and fat free mass (expressed over BMI (FFMᴮᴹᴵ) using bioelectrical impedance) in ...
adults; body mass index; cataract; chronic diseases; cities; comorbidity; coronary disease; diabetes; hospitals; hypertension; men; patients; questionnaires; risk factors; stroke; women; China
Abstract:
... OBJECTIVES: Multimorbidity is common in older hospitalized adults. To date, however, few studies have addressed multimorbidity in the older population of Chinese inpatients. We aimed to investigate the multimorbidity rate and associated risk factors in older adult inpatients in China. DESIGN, SETTING, PARTICIPANTS: This study was conducted in the medical wards of a tertiary-care hospital from. The ...
Human immunodeficiency virus 1; men; phylogeny; risk; Greece
Abstract:
... Our aim was to investigate the dispersal patterns and parameters associated with local molecular transmission clusters (MTCs) of subtypes A1 and B in Greece (predominant HIV-1 subtypes). The analysis focused on 1751 (28.4%) and 2575 (41.8%) sequences of subtype A1 and B, respectively. Identification of MTCs was based on phylogenetic analysis. The analyses identified 38 MTCs including 2–1518 subtyp ...
... Emerging evidence suggests that increasing dietary nitrate intake may be an effective approach to reduce blood pressure. Beetroot juice is often used to supplement dietary nitrate, whereas nitrate intake levels from habitual diet are low. An increase in the habitual intake of nitrate-rich vegetables may represent an alternative to nitrate supplementation. However, the effectiveness and acceptabili ...
... Gardnerella vaginalis (G. vaginalis) is the major bacteria detected in women with bacterial vaginosis (BV). Prevotella bivia (P. bivia) has been demonstrated to show a symbiotic relationship with G. vaginalis. Some men have been shown to be colonized with G. vaginalis in their urogenital or anorectal tracts, however genitourinary infections in males, including balanitis and urethritis, due to this ...
... Inflammation plays a key role and is one of the early steps in the pathogenesis of endothelial function, thereby increasing the risk of hypertension (HTN), coronary artery disease (CAD), stroke and several other risk factors of cardiovascular disease (CVD). We assessed the efficacy for improving cardiovascular health (blood pressure, inflammation and endothelial reactivity) over a 4-week intervent ...
... BACKGROUND: The current food system is responsible for significant environmental damage therefore, encouraging consumers to adopt an environmentally sustainable diet is a key public health challenge. Dietary guidelines have been developed that outline recommendations for purchasing and consuming food in an environmentally sustainable manner, but they have not yet been incorporated in UK national d ...
... Although several genome-wide interaction studies (GWIS) have been performed in specific European populations to understand the missing link between genetic and environmental factors for lung function, GWIS of Asian samples remain rare. Therefore, we performed a GWIS of exposure to air pollution to identify loci for lung function in Korean adult men. A total of 1826 adult men recruited from two hea ...
... PURPOSE: This study tried at identifying lifestyle patterns in a sample of Lebanese adults and investigating their association with metabolically healthy overweight and obesity (MHOv/O). METHODS: This study used data from a community-based survey of Lebanese adults living in Greater Beirut (n = 305). Dietary intake was assessed using an 80-item food frequency questionnaire. MHOv/O was defined as h ...
Asians; National Health and Nutrition Examination Survey; adults; animal proteins; carbohydrates; food intake; high carbohydrate diet; high density lipoprotein cholesterol; low fat diet; men; metabolic syndrome; odds ratio; optimal nutrition; plant proteins; population; protein intake; protein sources; risk factors; triacylglycerols; women; Korean Peninsula
Abstract:
... BACKGROUND: Because a moderate-carbohydrate diet reportedly has minimal risks, the substitution of carbohydrate for protein has been emphasized. Few studies have explored the effect of moderate-carbohydrate diets with higher protein intake in Asians, who typically consume a high-carbohydrate low-fat diet. Therefore, this study evaluated the associations of moderate- versus high- carbohydrate diets ...
berberine; blood pressure; body mass index; hypertrophy; lipid composition; lipids; men; metabolic syndrome; patients; placebos; randomized clinical trials; red yeast rice; women
Abstract:
... Increased left ventricular mass (LVM) is often present in metabolic syndrome (MS), also in the setting of well-controlled blood pressure (BP). Aim of the present study was to evaluate the efficacy of a nutraceutical combination of berberine, red yeast rice extract and policosanol (Armolipid Plus™, AP) in reducing LVM in patients with MS and left ventricular hypertrophy (LVH).In this multicenter, r ...
... PURPOSE: Poor sperm quality is a major contributor to infertility in heterosexual couples, but at present there are few empirical therapies. Several studies have examined the role of dietary factors and data from randomized controlled trials suggest that oral antioxidant therapy can improve some sperm parameters. Health benefits of lycopene supplementation have been proposed for a variety of healt ...
... Caffeine’s ergogenic effects on exercise performance are generally explained by its ability to bind to adenosine receptors. ADORA2A is the gene that encodes A₂A subtypes of adenosine receptors. It has been suggested that ADORA2A gene polymorphisms may be responsible for the inter-individual variations in the effects of caffeine on exercise performance. In the only study that explored the influence ...
Lilia Castillo-Martínez; Wendy D. Rodríguez-García; Dulce G. González-Islas; Arturo Orea-Tejeda; Mariel Lozada-Mellado; Juan Rodríguez-Silverio; Juan Gerardo Reyes-García
... In patients with heart failure, fluid alteration and low muscle strength frequently coexist because of their reduced physical activity and sedentary behavior; however, few studies have evaluated the effects of this coexistence on the prognosis of these patients. The aim of this study was to examine the independent association between fluid alteration and the low handgrip strength (HGS) index with ...
area; data analysis; men; questionnaires; sampling; students; women; Indonesia
Abstract:
... This is a non-experimental study which aims to obtain the academic procrastination data of students at Makassar, South Sulawesi, Indonesia. It used the non-random sampling method to obtain data from 586 students, consisting of 310 men and 276 women through questionnaires. The data were then descriptively analyzed using an academic procrastination scale, which was compiled and developed based on th ...
... To evaluate the association of early involvement in cooking activities with cooking skills in adulthood, the importance of different sources for the acquisition, and the link between cooking skills and healthy eating.Cross-sectional survey.A random sample of 3,659 Swiss adults (47% men; average age = 58.8 years).Self-reported cooking skills.ANOVA, Pearson correlations, t tests, and multiple regres ...
... Background: Combining resistance exercise (RE) with nutrient intake stimulates muscle protein net balance. However, it is still unclear whether the optimal timing of nutrient intake is before or after RE, especially on muscle protein breakdown (MPB) for an augmented muscle anabolic response. The aim of this study was to investigate the effect of a substantial mixed meal (i.e., nutrient- and protei ...
... Background: Dietary supplements purported to increase circulating nitric oxide are very popular among consumers. We determined the acute impact of two novel dietary supplements on plasma nitrate/nitrite (NOx) and nitrite alone. Methods: 20 men and women (age: 24 ± 5 years) ingested two different nitrate-rich supplements (Resync Recovery Blend at 7.5 g and 15 g; Resync Collagen Blend at 21 g), or p ...
... This study aimed to evaluate the effects of juçara juice on oxidative stress biomarkers and fatigue in a high-intensity interval training (HIIT) session. Fifteen physically active men were assigned to drink 250 mL of juçara juice or water (control) 1 h before exercise. Blood samples were collected 1 h prior to exercise, immediately post exercise, and 1 h post exercise. From the relative average ch ...
acute effects; acute exposure; adverse effects; air pollutants; air pollution; confidence interval; diastolic blood pressure; employment; environmental monitoring; hypertension; kriging; linear models; males; men; office workers; particulates; patients; systolic blood pressure; China
Abstract:
... Exposure to ambient particulate matter with a diameter of <2.5 μm (PM₂.₅) has been linked to increases in blood pressure. The aim of this study was to assess the effects of short-term exposure to PM₂.₅ on blood pressure in office workers in Beijing, China. A total of 4801 individuals aged 18–60 years underwent an annual medical examination between 2013 and 2017. Levels of air pollutants were obtai ...
... This randomized crossover study assessed the acute effects of almonds on postprandial glycemic, hormonal, and appetite responses in a sample of 7 men with type 2 diabetes (T2D). Participants completed 2 experimental visits during which a control (white bread, butter, cheese) and a test (white bread, almonds) meal were ingested. Energy, available carbohydrate, total lipid, and protein content were ...
... The purpose of this systematic review was to synthesize and evaluate current literature examining the effects of exercise on postprandial fat oxidation, as well as to provide future direction. A quantitative review was performed using meta-analytic methods. A moderator analysis was performed to investigate potential variables that could influence the effect of exercise on postprandial fat oxidatio ...
... PURPOSE: Older individuals suffer from low NADH levels. We have previously shown that nicotinamide riboside [NR; a NAD(P)(H) precursor] administration impaired exercise performance in young rats. It has been suggested that supplementation of redox agents exerts ergogenic effect only in deficient individuals. We hypothesized that old individuals would more likely benefit from NR supplementation. We ...
acetaminophen; adults; analysis of covariance; apples; blood sampling; body mass index; cross-over studies; fatty acid composition; food matrix; gastric emptying; glucose; high fat foods; hyperlipidemia; insulin; insulin secretion; lipoproteins; men; overweight; particle size; pectins; polyphenols; risk factors; test meals; women
Abstract:
... Whole apples are a source of pectin and polyphenols, both of which show potential to modulate postprandial lipaemia (PPL). The present study aimed to explore the effects of whole apple consumption on PPL, as a risk factor for CVD, in generally healthy but overweight and obese adults. A randomised, crossover acute meal trial was conducted with seventeen women and nine men (mean BMI of 34·1 (sem 0·2 ...
... The objective of this study was to compare the effects of consuming a 16% maltodextrin+fructose+pectin-alginate (MAL+FRU+PEC+ALG) drink against a nutrient-matched maltodextrin+fructose (MAL+FRU) drink on enterocyte damage and gastrointestinal permeability after cycling in hot and humid conditions. Fourteen recreational cyclists (7 men) completed 3 experimental trials in a randomized placebo-contro ...
Roberta Zupo; Fabio Castellana; Francesco Panza; Luisa Lampignano; Isanna Murro; Carmen Di Noia; Vincenzo Triggiani; Gianluigi Giannelli; Rodolfo Sardone; Giovanni De Pergola
... Much research suggests that Mediterranean eating habits and lifestyle contribute to counteract the risk of chronic diseases while promoting longevity, but little information is available on the effects of the Mediterranean diet (Med-Diet) on thyroid function, particularly among overweight/obese subjects. Nevertheless, consistent data reported a slight increase in serum levels of the thyroid-stimul ...
Ismael Alvarez-Alvarez; Estefanía Toledo; Oscar Lecea; Jordi Salas-Salvadó; Dolores Corella; Pilar Buil-Cosiales; María Dolores Zomeño; Jesús Vioque; J. Alfredo Martinez; Jadwiga Konieczna; Francisco J. Barón-López; José López-Miranda; Ramon Estruch; Aurora Bueno-Cavanillas; Ángel M. Alonso-Gómez; Josep A. Tur; Francisco J. Tinahones; Lluís Serra-Majem; Vicente Martín; Manuel Ortega-Calvo; Clotilde Vázquez; Xavier Pintó; Josep Vidal; Lidia Daimiel; Miguel Delgado-Rodríguez; Pilar Matía; José I. González; Andrés Díaz-López; Indira Paz-Graniel; Miguel A. Muñoz; Montse Fito; Salvador Pertusa-Martinez; Itziar Abete; Antonio García-Ríos; Emilio Ros; Miguel Ruiz-Canela; Miguel Á. Martínez-González
... PURPOSE: Cardiovascular disease remains the global leading cause of death. We evaluated at baseline the association between the adherence to eight a priori high-quality dietary scores and the prevalence of individual and clustered cardiovascular risk factors (CVRF) in the PREDIMED-Plus cohort. METHODS: All PREDIMED-Plus participants (6874 men and women aged 55–75 years, with overweight/obesity and ...
... The aging process is associated with several chronic diet-related complications, including cardiovascular diseases. Therefore, the objective was to examine the association between DASH and Mediterranean dietary pattern (MDP) on cardiovascular risk factors and inflammatory markers in older adult men.A cross-sectional study was performed on 357 older adult men who were randomly selected from health ...
Marta Gómez Sánchez; Leticia Gómez Sánchez; Maria C Patino-Alonso; Rosario Alonso-Domínguez; Natalia Sánchez-Aguadero; Cristina Lugones-Sánchez; Emiliano Rodríguez Sánchez; Luis García Ortiz; Manuel A Gómez-Marcos
... The objective of this study is to analyze the influence of adherence to the Mediterranean diet (MDA) and its components on early vascular aging (EVA) in a Spanish population sample free of cardiovascular disease and to analyze the differences by sex. Methods: We recruited 501 individuals aged 35–75 without cardiovascular disease by random sampling (55.90 ± 14.24 years, 49.70% men). EVA was defined ...
adolescents; adults; beans; beverages; children; desserts; dietary surveys; energy intake; females; food groups; food intake; food records; household income; men; milk; national surveys; nutritive value; rice; sweets; vegetables; women; Brazil
Abstract:
... To evaluate differences in food consumption of Brazilian adults according to the presence of children and adolescents in the household. Averages of two non-consecutive days of food records from the first Brazilian National Dietary Survey were analysed and classified into eighteen food groups according to nutritional characteristics and use in diet. We compared the mean percentage contribution to t ...
... Advanced glycation end products (AGEs), which are the products of a non-enzymatic reaction between reducing sugars and other macromolecules, are critical in aging, as well as metabolic and degenerative diseases. To assess the involvement of AGEs in glaucoma, skin autofluorescence (sAF) level, which is a measurement of AGEs’ accumulation, was compared among Japanese patients with glaucoma (316 with ...
Japan; adulthood; age; childhood; confidence interval; eating habits; elderly; fruits; health behavior; men; regression analysis; vegetable consumption; vegetables; women
Abstract:
... Although adverse childhood experiences (ACEs) have been linked to negative health behaviors in adulthood, few studies have investigated if the impact continues until late adulthood. We examined the association between ACEs and fruit and vegetable intake (FVI) among older adults in Japan.Data came from the Japan Gerontological Evaluation Study (JAGES), 2013 in which 24,271 individuals aged ≥65 year ...
National Health and Nutrition Examination Survey; age; alanine transaminase; alcohol drinking; analysis of covariance; aspartate transaminase; blood serum; confidence interval; databases; diabetes; educational status; eggs; energy intake; fatty liver; gender; hypertension; income; liver; men; models; odds ratio; pathogenesis; physical activity; poverty; races; regression analysis; risk factors; triacylglycerols
Abstract:
... We evaluated the association of egg consumption with liver tests (LTs) and non-alcoholic fatty liver disease (NAFLD). This relationship is poorly documented.The National Health and Nutrition Examination Survey (NHANES, 2005–2010) database was used. Analysis of covariance, adjusted linear and logistic regression models were used.Of the 14,369 participants, 46.8% were men and 45.2% had NAFLD. After ...
... BACKGROUND: Excessive body fat is the leading cause of many metabolic disorders. Therefore, assessing levels of body fat associated with risk of disease in specific populations is crucial. The present study aimed to identify optimal cut-off values of body fat composition including total body fat, body fat percentage, visceral fat, and trunk fat, in order to predict metabolic risk in the Qatari pop ...
... Ultrasonography-derived cross-sectional area (CSA) and echo intensity (EI) are increasingly utilized by investigators to study muscle size and quality, respectively. We sought to examine age, sex, and region (proximal, middle, distal) differences in vastus lateralis and rectus femoris CSA and EI, and determine whether correction for subcutaneous fat thickness influences the magnitude of EI differe ...
blood; blood sampling; bovine serum albumin; cholesterol; epidemiology; fractionation; high performance liquid chromatography; human health; humans; lipoproteins; men; perfluorohexane sulfonic acid; perfluorooctane sulfonic acid; perfluorooctanoic acid; tandem mass spectrometry; ultracentrifugation; volunteers; women
Abstract:
... Perfluoroalkyl (PFAS) substances are widespread in the environment and in organisms. The fact that exposure to PFAS is associated with elevated cholesterol levels is a major concern for human health. Previous investigations, in which bovine serum albumin was frequently studied, indicate that PFOS, PFOA and PFNA bind to serum albumin. However, it is critical to know whether these and other PFAS hav ...
Koreans; adults; alcohol drinking; alcohols; alleles; body mass index; calcium; carbohydrates; cross-sectional studies; food frequency questionnaires; genetic models; genetic variation; genome-wide association study; hypertriglyceridemia; lifestyle; lipid composition; males; men; single nucleotide polymorphism; smoking (habit); triacylglycerols
Abstract:
... Plasma triglyceride (TG) concentrations are markedly higher among Asians, which may be associated with the interaction of genetics and lifestyle factors.The purpose of this study was to investigate the genetic variants that have a strong association with plasma TG concentrations from genome-wide association study and to identify lifestyle interactions with the genetic variants that are associated ...
CD4-positive T-lymphocytes; Chinese people; HIV infections; Haemophilus; Human immunodeficiency virus; Neisseria; Streptococcus; antiretroviral agents; correlation; demography; dysbiosis; hematologic tests; men; microbiome; microorganisms; pathogens; patients; prognosis; saliva; sampling; sequence analysis; species diversity; therapeutics; viral load
Abstract:
... Human immunodeficiency virus (HIV) infections are spiking in Chinese young men who have sex with men (MSM). To explore alterations in the salivary microbiome and its correlation with demographic characteristics, CD4+ T cell count and viral load (VL) in HIV infections, samples of unstimulated whole saliva were analyzed by 16S rRNA gene sequencing using the Illumina MiSeq platform in 20 HIV newly in ...
... Xenobiotic metabolism at menopause is an under-investigated topic, albeit women spend one-third of their life in the postmenopausal period. The present study examined the effect of menopause on the in vivo activities of CYP1A2, CYP2A6, xanthine oxidase (XO) and N-acetyltransferase-2 (NAT2) xenobiotic metabolizing enzymes. Enzyme activity was determined in 152 non-smoking volunteers following oral ...
age; air pollutants; confidence interval; frequency; hypertension; men; models; odds ratio; prevalence; regression analysis; satellites; sleep; women; China
Abstract:
... We aimed to assess if snoring and ambient air pollutants were jointly associated with prevalent hypertension in a cross-sectional study.A total of 28440 participants aged 18–79 years were obtained from the Henan Rural Cohort. Snoring evaluated using Pittsburgh sleep quality index (PSQI) scale was classified into ‘Never’, ‘<3 times/week’ and ‘≥3 times/week’ groups. Concentrations of air pollutants ...
Blacks; Chinese people; Hispanics; Whites; adults; air pollution; atherosclerosis; cities; diastolic blood pressure; ethnic differences; hypertension; men; nitrogen oxides; ozone; particulates; women; United States
Abstract:
... Racial/ethnic disparities in blood pressure and hypertension have been evident in previous studies, as were associations between race/ethnicity with ambient air pollution and those between air pollution with hypertension. The role of air pollution exposure to racial/ethnic differences in hypertension has not been explored.To assess the potential mediating effects of ambient air pollution on the as ...
Cyprus; age; data analysis; females; hepatitis A; laboratories; males; men; monitoring; pathogens; population; public health; vaccination; young adults; Europe
Abstract:
... Background: Outbreaks of acute hepatitis A (AHA) have recently been reported in Europe among men who have sex with men (MSM). The aim of this work was to evaluate, for the first time, trends in the reported cases of AHA in Cyprus over the last seven years. Methods: We retrospectively studied all people reported with AHA in Cyprus between January 2013 and December 2019. Demographic data, type of tr ...
Alice E. Thackray; Scott A. Willis; Aron P. Sherry; David J. Clayton; David R. Broom; Mayada Demashkieh; Jack A. Sargeant; Lewis J. James; Graham Finlayson; David J. Stensel; James A. King
acute effects; age; appetite; body mass index; breakfast; cross-over studies; energy intake; exercise; food choices; men; questionnaires; research; swimming; walking; water; water temperature; women
Abstract:
... Single bouts of land-based exercise (for example, walking, running, cycling) do not typically alter post-exercise energy intake on the day of exercise. However, anecdotal and preliminary empirical evidence suggests that swimming may increase appetite and energy intake. This study compared the acute effects of swimming on appetite, energy intake, and food preference and reward, versus exertion-matc ...
... The identification of more than three perfumes is difficult and no analytical tool can completely replace the human olfactory system for fragrance classification. Indeed, no analytical system can mimic the human fragrance perception, being the recognition of perfume aroma patterns by conventional or sensor-based analytical tools a challenging task. For the perfume sector, the possibility of applyi ...
... Organoid cultures derived from primary human tissues facilitate the study of disease processes and the development of new therapeutics. Most men with cystic fibrosis (CF) are infertile due to defects in the epididymis and vas deferens; however, the causative mechanisms are still unclear. We used human epididymis epithelial cell (HEE) organoids and polarized HEE cell cultures to assay the CF transm ...
... BACKGROUND: Paraprostatic cysts are large structures that develop between the prostate gland and urinary bladder, usually in older, intact dogs. Their incidence is reported to be 1.1–5.3% in dogs with prostatic disease. The aetiology of paraprostatic cysts is not fully understood, but they are believed to develop from the uterus masculinus. Whereas the uterus masculinus has been reported to commun ...
DNA; HIV infections; Human immunodeficiency virus; Papillomaviridae; blood sampling; cities; confidence interval; genotype; genotyping; illicit drugs; males; men; models; odds ratio; questionnaires; risk; sexually transmitted diseases; vaccination; vaccines; warts; China
Abstract:
... Men who have sex with men (MSM), especially those infected with human immunodeficiency virus (HIV), are at disproportionate risk for human papillomavirus (HPV) infection. Data about anal HPV prevalence among MSM in southern China are limited.MSM were recruited between January 1 and August 31, 2017 in three metropolitan cities: Guangzhou, Shenzhen and Wuxi. A self-completed tablet-based questionnai ...
adults; androstenedione; biotransformation; chemical species; cytochrome P-450; detection limit; electrospray ionization mass spectrometry; high performance liquid chromatography; homeostasis; humans; hydroxylation; male reproductive system; men; metabolites; testosterone; ultra-performance liquid chromatography; urinalysis; urine
Abstract:
... Testosterone regulates the male reproductive system and acts directly or indirectly on nearly all systems during fetal, pubertal and adult life. Testosterone homeostasis depends on its synthesis and degradation. The major biotransformation reactions are hydroxylation by different cytochrome P450 (CYP) isoforms. There are no described methods to determine the profile of testosterone-hydroxylated me ...
... The study tested whether anserine (beta-alanyl-3-methyl-l-histidine), the active ingredient of chicken essence affects exercise-induced oxidative stress, cell integrity, and haematology biomarkers. In a randomized placebo-controlled repeated-measures design, ten healthy men ingested anserine in either a low dose (ANS-LD) 15 mg·kg⁻¹·bw⁻¹, high dose (ANS-HD) 30 mg·kg⁻¹·bw⁻¹, or placebo (PLA), follow ...
... Our recent clinical study suggested that polyphenol-rich purple potatoes lowered postprandial glycemia and insulinemia compared to yellow potatoes. Here, 17 healthy male volunteers consumed yellow potatoes with or without purple potato extract (PPE, extracted with water/ethanol/acetic acid) rich in acylated anthocyanins (152 mg) and other phenolics (140 mg) in a randomized cross-over trial. Ethano ...
Mónica Y. Herrera-Sotero; Carlos D. Cruz-Hernández; Rosa M. Oliart-Ros; José L. Chávez-Servia; Rosa I. Guzmán-Gerónimo; Vanessa González-Covarrubias; Marian Cruz-Burgos; Mauricio Rodríguez-Dorantes
... Background: Breast and prostate cancer are frequently diagnosed neoplasias in women and men around the world. The signaling of the androgen receptor (AR) influences the development of both tumors. Since therapies focused to block the receptor’s activity have not been fully effective, and have shown side effects, therapies based on natural compounds are promissory complementary alternatives in its ...
antibodies; confidence interval; enzyme-linked immunosorbent assay; human resources; men; monitoring; professionals; rabies; secondary immunization; seroconversion; vaccination; vaccines; women
Abstract:
... Vaccination against rabies and routine antibody testing of subjects participating in programs for the surveillance and control of rabies in animals is strongly recommended. The scope of this study is to describe the antibody level as measured by a commercial enzyme-linked immunosorbent assay (ELISA) after primary and booster intramuscular vaccination with a purified vero-cell rabies vaccine (PVRV) ...
... Background: Antioxidant potential is defined as the ability to neutralize oxygen free radicals that are generated in excess due to environmental influences. The body’s defense mechanisms often require support in preventing the effects of oxidative stress. The literature data suggest that curcumin has antioxidant activity that can significantly reduce oxidative stress levels. The aim was to assess ...
demographic statistics; education; elderly; employment; family size; gender; men; models; nutrition surveys; tea; urbanization; women; China
Abstract:
... The purpose of this study is to investigate the effects of demographic variables on tea consumption in China. A total of 12,745 samples collected from the China Health and Nutrition Survey in 2011 and a double hurdle model were used to analyze the effects of demographic variables on the extent of tea participation and consumption quantity for men and women. The results of this study indicate that ...
adults; age; bias; body fat; clinical nutrition; dual-energy X-ray absorptiometry; equations; females; mass; men; models; overweight; validity; variability; weight; women
Abstract:
... Body composition assessment has large variability. A dual-energy x-ray absorptiometry (DXA) derived four compartment (4C) method has been developed as an accurate and reliable method for assessing body composition in overweight/obese adults. This investigation was aimed at understanding the validity of the DXA-derived 4C equation for use in normal weight individuals, stratified by sex, and with va ...
... This study assessed the nutritional status among householders in urban South Tarawa and rural Butaritari in Kiribati. In this cross-sectional study, we assessed energy and nutrient intakes, food variety scores, and dietary diversity scores of men and women from 468 households randomly selected in South Tarawa (n = 161) and Butaritari (n = 307) using a 24-hour dietary recall. Nutrient adequacy rati ...
... BACKGROUND: Recognition of discrepancies between men and women in nutritional intake is important to tackle food and nutrition insecurity and the often-double burden of malnutrition. The purpose of this study was to assess nutritional status and dietary intake of the Lao population, with a focus on possible influences of gender. METHODS: Dietary intake was assessed in a national cross-sectional st ...
adults at risk; body water; confidence interval; cross-sectional studies; educational status; elderly; epidemiological studies; kidney diseases; men; muscle strength; nutrition; odds ratio; regression analysis; risk reduction; urine; women
Abstract:
... BACKGROUND: Dehydration appears to affect muscle strength and weakness, although its influence on exhaustion remains unclear. The present study aimed to quantify the association between hydration status and exhaustion among older adults. METHODS: A cluster sampling approach was used, representing Portuguese older adults (≥65 years) according to age, sex, education level and region within the Nutri ...
ecosystem services; elderly; gender; green infrastructure; human health; men; planning; recreation; urban areas; urban population; visual perception; women; young adults; Sweden
Abstract:
... Neighbourhood green space is an important asset for the urban population, providing valuable ecosystem services such as supporting human health. Distance or access to urban green areas is well established as being important for the potential use of the area but how different demographic groups move within greenspace is still somewhat unknown.Previous studies have shown that there are gender as wel ...
air quality; attitudes and opinions; cities; energy; energy costs; income; men; subsidies; surveys; willingness to pay; China
Abstract:
... Under the background of removing the subsidies for the new energy vehicles step by step and increasing the subsidies for the charging facilities in China, getting a comprehensive understanding on public's perception and attitudes towards new energy vehicles and charging facilities is significant to the policymakers. To fulfil these goals, we design and perform a random survey in Beijing, Shanghai, ...
HIV infections; Hepatitis C virus; Human immunodeficiency virus; antiviral agents; interferons; liver diseases; men; mixed infection; patients; physicians; relapse; researchers; therapeutics
Abstract:
... Direct-acting antivirals (DAAs) have tremendously improved the treatment of hepatitis C virus (HCV) infections also in human immunodeficiency virus (HIV)-positive individuals. Curing HCV infection is of particular importance in HIV-positive individuals as liver disease progression is accelerated in the course of concomitant HIV infection. Former challenges, such as safety and tolerability as well ...
... Arsenic and selenium elements play extremely important roles in organisms. Too high As concentration in blood may lead to functional disorders within organs, including cancer. Arsenic is designated as a Group 1 human carcinogen by the International Agency for Research on Cancer that has established causal role of arsenic in cancers of the urinary bladder, lung, and skin in humans. In contrast, Se ...
... The aim of the present study was to determine changes occurring in the erythrocyte concentrations of arsenic (As), cadmium (Cd) and lead (Pb) in highly trained males, moderately trained males and sedentary men living in the same area of Extremadura (Spain). Thirty sedentary subjects (24.34 ± 3.02 years) with no sports practice and a less active lifestyle formed the control group (CG). Twenty-four ...
biodiversity; bycatch; coastal zone management; coral reefs; federal government; financial economics; fish; fish nets; fisheries law; interviews; lobster fisheries; marine environment; men; traditional technology; women; Brazil
Abstract:
... Ghost fishing, the ability of fishing equipment to continue to capture organisms even after it is no longer controlled, leads to serious marine impacts, including bycatch, which contributes to biodiversity loss. Insistent complaints from artisanal fisher in the state of Bahia, Brazil, concerning the impacts of nets lost or abandoned by fisher from other regions that operate in their traditional fi ...
... Mental stress (MS) is related to endothelial dysfunction in overweight/obese men. It is believed that the pro-oxidant profile, associated with an imbalance in the vascular remodeling process, may contribute to deleterious effects of MS on endothelial function. However, it is unknown whether administration of ascorbic acid (AA), a potent antioxidant, can prevent oxidative and remodeling dysfunction ...
cognition; extracts; females; journals; males; men; spatial data; testing; women
Abstract:
... The aim of this study was to investigate whether different expressions of landmarks and paths have different influences on the navigational efficiency and the cognitive load of indoor maps. The study tested 80 subjects by indoor path discovery experiments and measured their cognitive loads with the Cooper–Harper scale. According to the results, we extracted some key landmarks from all landmarks of ...
National Health and Nutrition Examination Survey; adults; antioxidant activity; cardiovascular diseases; copper; females; high density lipoprotein cholesterol; iron; males; men; regression analysis; risk factors; selenium; women; zinc; United States
Abstract:
... The trace minerals zinc, copper, iron, and selenium are essential micronutrients, and because of their antioxidant activity, they are hypothesized to improve cardiovascular health. However, their associations with different risk levels for cardiovascular diseases are less clear. Data from the National Health and Nutrition Examination Survey 2007–2014 were used. In this study, the ratio of total ch ...
blood serum; chemiluminescence; cross-sectional studies; dose response; hospitals; magnesium; men; odds ratio; public health; renal calculi; ultrasonics; women; China
Abstract:
... Kidney stones, a painful and costly disease, have become a public health problem worldwide. The aim of this study was to evaluate the association between serum magnesium levels and the prevalence of kidney stones in a large population context. This study was conducted in Xiangya Hospital, Central South University in Changsha, Hunan, China, between October 2013 and December 2015. A total of 6228 su ...
body mass index; confidence interval; cross-sectional studies; eating habits; elderly; energy intake; fish; food frequency questionnaires; food intake; fruits; long term care; macroalgae; males; men; miso; mushrooms; noodles; odds ratio; physical activity; pickles; principal component analysis; regression analysis; rice; sarcopenia; socioeconomic status; soups; soybeans; tofu; women; Japan
Abstract:
... OBJECTIVES: To identify the dietary patterns among community-dwelling Japanese older adults and to explore the association between these patterns and sarcopenia. DESIGN: Cross-sectional study. SETTING: Kashiwa city, Chiba prefecture, Japan. PARTICIPANTS: Community-dwelling older adults (n = 1241) aged 65 years and over who were not eligible for long-term care. MEASUREMENTS: Dietary intake was asse ...
... One in six couples experience fertility problems. Environmental factors may affect reproductive health; however, evidence is lacking regarding drinking water nitrates and outcomes of male and female fertility. The aim of this study was to investigate if exposure to nitrates in drinking water is associated with adverse reproductive outcomes in humans, and animals of fertile age. We conducted a syst ...
... This study aimed to assess health related quality of life (HRQoL) in adult patients with Crohn’s disease (CD), considering disease severity and gender differences, and also its relationship with nutritional status. Consecutive adult patients aged 18–65 years with CD were recruited. Disease activity was clinically defined by the Crohn’s Disease Activity Index (CDAI) in active and quiescent phases. ...
age; bioelectrical impedance; biomarkers; body fat; educational status; elderly; food frequency questionnaires; healthy eating habits; height; hip circumference; inflammation; males; marital status; men; nutrients; nutritional adequacy; obesity; population; protein sources; regression analysis; vegetables; waist; waist-to-height ratio; waist-to-hip ratio; weight; women
Abstract:
... Poor diet quality and obesity, especially abdominal obesity, have been associated with systemic inflammation. The neutrophil-to-lymphocyte Ratio (NLR) is an available and inexpensive inflammation biomarker. The aim of the present study was to determine the association of dietary patterns and obesity with an inflammatory state. A group of 1747 Spanish noninstitutionalized older adults individuals w ...
Singapore; age; blood lipids; blood pressure; body composition; body mass index; cholesterol; energy intake; ingestion; lifestyle; lipoproteins; men; multivariate analysis; nationalities and ethnic groups; nutrients; obesity; population; questionnaires; risk factors; triacylglycerols; waist circumference; women
Abstract:
... Eating faster is associated with greater body mass index (BMI), but less is known about the relationships between eating rate, energy intake, body composition, and cardio-metabolic risk factors in different Asian ethnic groups. Using data from the Singapore Multi-Ethnic Cohort (n = 7011; 21–75 y), we investigated associations between self-reported eating rate (SRER), with energy intake, body compo ...
Elettra Mancuso; Maria Perticone; Rosangela Spiga; Carolina Averta; Mariangela Rubino; Teresa Vanessa Fiorentino; Sofia Miceli; Gaia Chiara Mannino; Angela Sciacqua; Elena Succurro; Francesco Perticone; Giorgio Sesti; Francesco Andreozzi
... Magnesium (Mg²⁺) levels are associated with insulin resistance, hypertension, atherosclerosis, and type 2 diabetes (T2DM). We evaluated the clinical utility of physiological Mg²⁺ in assessing subclinical cardiovascular organ damage including increased carotid artery intima- media thickness (c-IMT) and left ventricular mass index (LVMI) in a cohort of well-characterized adult non-diabetic individua ...
Dietary Approaches to Stop Hypertension diet; Mediterranean diet; abdominal fat; adults; body mass index; compliance; cross-sectional studies; eating habits; food frequency questionnaires; men; neurodegenerative diseases; obesity; waist circumference; women
Abstract:
... BACKGROUND: Recently, a new eating pattern called as “Mediterranean-DASH Intervention for Neurodegenerative Delay (MIND)” has been coined. Emerging studies are examining this dietary pattern with chronic conditions. We aimed to investigate the association between the MIND diet score and general and central obesity among adults. METHODS: This cross-sectional study was conducted in a framework of th ...
United States Environmental Protection Agency; anemia; carbon; elderly; erythrocytes; hemoglobin; ionizing radiation; men; monitoring; particulates; radioactivity; statistical models
Abstract:
... Although ionizing radiation is known to have detrimental effects on red blood cells, the effect of environmental radioactivity associated with ambient particulate matter (PM) is unknown. We hypothesized that exposure to ambient PM-associated beta particle radioactivity (PRᵦ) would be associated with a lower hemoglobin concentration. We studied 1.704 participants from the Normative Aging Study (NAS ...
air temperature; ambient temperature; body mass index; clinical examination; humans; longitudinal studies; male fertility; men; models; semen banks; semen quality; sperm concentration; spermatogenesis; spermatozoa; volunteers; China
Abstract:
... Semen quality is a vital determinant for male fertility. The process of spermatogenesis is highly sensitive to fluctuations in temperature. However, the impact of ambient temperature on semen quality remains unclear. We aimed to quantitatively assess the association between ambient temperature and semen quality. Using data from Hubei provincial human sperm bank in Wuhan, China, we conducted a long ...
... Previous studies linking biomass fuel use to hypertension have been inconsistent. We investigated the association between biomass fuel use and the risk of hypertension and blood pressure measures in older Chinese people.The prospective cohort study of the Chinese Longitudinal Healthy Longevity Survey (CLHLS) included participants aged 65 years and older in 2011/2012 who were followed up until 2014 ...
adiposity; adults; body mass index; coronary disease; educational status; experimental design; longitudinal studies; men; multivariate analysis; risk factors; screening; variance; waist-to-hip ratio; women
Abstract:
... The body adiposity index (BAI) was recently proposed as a better indicator of body adiposity than body mass index in adults. The association between BAI and cardiometabolic risk factors has been widely investigated. However, the strength and magnitude of these associations varied as a function of the endpoint evaluated, the study design, the population investigated, and the cut-off points used. Th ...
... PURPOSE: Fatty acid composition in blood and adipose tissue (AT) is a useful biomarker of dietary fat quality. However, circulating saturated fatty acids (SFA) and monounsaturated fatty acids (MUFA) have been proposed to also reflect carbohydrate-induced de novo lipogenesis (DNL) and stearoyl-CoA desaturase (SCD) activity. We aimed to test the hypothesis that high carbohydrate intake is related to ...
National Health and Nutrition Examination Survey; adults; chi-square distribution; cross-sectional studies; data analysis; health surveys; income; ingestion; issues and policy; men; mental health; nutrition; objectives; population; regression analysis; research; risk; rural areas; socioeconomic factors; socioeconomic status; teachers; women; Korean Peninsula
Abstract:
... OBJECTIVES: This study investigated whether commensality (eating a meal with others) is associated with mental health (depression, suicidal ideation) in Korean adults over 19 years old. METHODS: Our study employed data from the sixth and seventh Korea National Health and Nutritional Examination Surveys (KNHANES) for 2013, 2015, and 2017. The study population consisted of 14,125 Korean adults (5854 ...
... Visceral obesity is a marker of dysfunctional adipose tissue and ectopic fat infiltration. Many studies have shown that visceral fat dysfunction has a close relationship with cardiovascular disease. For a better identification of visceral adiposity dysfunction, the visceral adiposity index (VAI) is used. Coronary artery calcium score (CACS) is known to have a strong correlation with the total plaq ...
Guillermo Mena-Sánchez; Nancy Babio; Nerea Becerra-Tomás; Miguel Á. Martínez-González; Andrés Díaz-López; Dolores Corella; Maria D. Zomeño; Dora Romaguera; Jesús Vioque; Ángel M. Alonso-Gómez; Julia Wärnberg; José A. Martínez; Luís Serra-Majem; Ramon Estruch; Rosa Bernal; José Lapetra; Xavier Pintó; Josep A. Tur; José Lopez-Miranda; Naomi Cano-Ibáñez; Jose J. Gaforio; Pilar Matía-Martín; Lidia Daimiel; José L. Llisterri Caro; Josep Vidal; Clotilde Vázquez; Emili Ros; Ana Garcia Arellano; Antoni Palau; Rebeca Fernández-Carrión; Karla A. Pérez-Vega; Marga Morey; Manoli García de la Hera; Jessica Vaquero-Luna; Francisco J. Carmona-González; Itziar Abete; Jacqueline Álvarez-Pérez; Rosa Casas; José C. Fernández-García; José M. Santos-Lozano; Emili Corbella; Antoni Sureda; Miguel Ruiz-Canela; Rocio Barragán; Albert Goday; Marian Martín; María C. Altozano Rodado; Estefanía Toledo; Montse Fitó; Jordi Salas-Salvadó; PREDIMED-PLUS investigators
... The prevalence of hyperuricemia has increased substantially in recent decades. It has been suggested that it is an independent risk factor for weight gain, hypertension, hypertriglyceridemia, metabolic syndrome (MetS), and cardiovascular disease. Results from epidemiological studies conducted in different study populations have suggested that high consumption of dairy products is associated with a ...
Koreans; adults; anthocyanidins; body fat; body mass index; confidence interval; diet recall; flavanols; flavanones; flavonols; food intake; isoflavones; men; obesity; odds ratio; proanthocyanidins; surveys; waist circumference; women; Korean Peninsula
Abstract:
... This study aimed to investigate the association between dietary flavonoid intake and the prevalence of obesity using body mass index (BMI), waist circumference, and percent body fat (%BF) according to sex among Korean adults. Based on the Korean Health and Nutrition Examination Survey 2008–2011, 23 118 adults in Korea were included. Dietary intakes were obtained using 24-h dietary recall data. A h ...
... The present study was carried out to determine whether the dietary insulin index (DII) and dietary insulin load (DIL) are related to psychological disorders in a cross-sectional study among adults. A total of 3172 Iranian adults (age range of 18–55 years) were included. Data on dietary intakes were collected using a validated dish-based 106-item semi-quantitative FFQ. DII and DIL were calculated u ...
adults; body fat; body mass index; chronic diseases; cross-sectional studies; demography; food frequency questionnaires; hyperinsulinemia; insulin; men; models; obesity; waist circumference; women
Abstract:
... PURPOSE: Hyperinsulinemia is linked to the development of various chronic diseases, especially obesity given to the role of insulin responses in body fat accumulation; hence, the current study aimed to examine the association of insulinemic potential of the diet with general and abdominal obesity among a large population of Iranian adults. METHODS: This cross-sectional study was carried out among ...
adults; cohort studies; confidence interval; docosahexaenoic acid; eating habits; eicosapentaenoic acid; fast foods; fish; folic acid; food frequency questionnaires; fruits; high fat dairy products; least squares; legumes; longitudinal studies; magnesium; males; men; mental depression; nutritional intervention; nuts; odds ratio; principal component analysis; red meat; risk reduction; snacks; soft drinks; takeout foods; vegetables; white bread; women; zinc
Abstract:
... There have been inconsistent findings on the association between dietary patterns and depressive symptoms (DepS). In addition, studies have used single analysis methods to identify dietary patterns. In the current study, we aimed to determine the association between dietary patterns, derived by principal component analysis (PCA), reduced-rank regressions (RRR) and partial least-squares (PLS), and ...
adults; affordability; cakes; carbonated beverages; eating habits; eggs; fast foods; fish; flat breads; grains; households; income; meat; men; nationalities and ethnic groups; noodles; nutrition risk assessment; nutrition surveys; overweight; principal component analysis; ready-to-eat foods; urban areas; vegetables; women; Malaysia
Abstract:
... To investigate the association between dietary patterns (DP) and overweight risk in the Malaysian Adult Nutrition Surveys (MANS) of 2003 and 2014. DP were derived from the MANS FFQ using principal component analysis. The cross-sectional association of the derived DP with prevalence of overweight was analysed. Malaysia. Nationally representative sample of Malaysian adults from MANS (2003, n 6928; 2 ...
adults; at-risk population; blood glucose; body mass index; energy intake; fasting; food frequency questionnaires; food intake; gender; glucose; healthy diet; insulin; insulin resistance; men; menopause; nutrition risk assessment; physical activity; risk reduction; Iran
Abstract:
... To assess the association between dietary patterns no single food or group, and risk of insulin resistance (Fasting blood sugar (FBS), Fasting insulin, 2h-glucose, 2h-insulin and HOMA-IR).In a cross-sectional, population-based study in Tehran, Iran, 2016–2017. Adults (n = 1500, 38% men) mean age 43.72 ± 14.9 years. Dietary intake was collected by semi-quantitative food frequency questionnaire and ...
adults; antioxidant activity; body mass index; cohort studies; cross-sectional studies; fatty liver; humans; inflammation; logit analysis; men; mushrooms; standard deviation; ultrasonics; China
Abstract:
... Animal studies have suggested that mushroom intake can alleviate non-alcoholic fatty liver disease (NAFLD) due to its anti-inflammatory and antioxidant properties. However, the association between mushroom intake and NAFLD is unknown in humans. We aimed to investigate the association of mushroom intake with NAFLD among Chinese adults. This is a cross-sectional study of 24 236 adults (mean (standar ...
blood pressure; elderly; epidemiology; food frequency questionnaires; fruit consumption; fruits; genome; hazard ratio; hyperglycemia; hypertriglyceridemia; men; metabolic syndrome; obesity; regression analysis; risk; risk reduction; vegetable consumption; women
Abstract:
... PURPOSE: This study examined the association between fruit and vegetable consumption and the risk of metabolic syndrome (MetS) and its components in middle-aged and older adults using data from the Korean Genome and Epidemiology Study. METHODS: A total of 5688 participants aged 40–69 years without MetS at baseline were recruited and followed for 8 years. Fruit and vegetable consumption was assesse ...
colorectal neoplasms; confidence interval; food frequency questionnaires; gluten; grain consumption; hazard ratio; men; protein content; refined grains; risk; sweets; whole grain foods; women; United States
Abstract:
... PURPOSE: Evidence supports a role of whole grains in colorectal cancer (CRC) prevention, but the association between gluten intake and CRC risk in healthy populations is unclear. We examined the association of grain and gluten intake with risk of CRC overall and by subsite among Cancer Prevention Study-II Nutrition Cohort participants. METHODS: In 1999, 50,118 men and 62,031 women completed food f ...