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- Author:
- Zhang, Jing; Shen, Biao; Chen, Liqun; Chen, Lingdong; Meng, Yangsheng; Feng, Jie
- Source:
- Colloids and surfaces 2019 v.175 pp. 65-72
- ISSN:
- 0927-7765
- Subject:
- apoptosis; blood serum; bovine serum albumin; colloids; disulfide bonds; doxorubicin; drug carriers; human cell lines; nanoparticles; neoplasm cells; neoplasms; porous media; silica
- Abstract:
- ... A multifunctional envelope-type mesoporous silica nanoparticle (MSN) was delicately designed for subcellular co-delivery of drug and therapeutic peptide to tumor cells. Firstly, a kind of cell apoptosis peptide (KLAKLAK)2 (KLA) was anchored on surface of MSN via disulfide bond to obtain MSN-SS-KLA. Subsequently, anticancer drug doxorubicin hydrochloride (DOX) was loaded into the pores of MSN-SS-KL ...
- DOI:
- 10.1016/j.colsurfb.2018.11.071
-
https://dx.doi.org/10.1016/j.colsurfb.2018.11.071
- Author:
- Lee, Taek; Lee, Yeonju; Park, Sun Yong; Hong, Keonyoung; Kim, Younghun; Park, Chulhwan; Chung, Yong-Ho; Lee, Min-Ho; Min, Junhong
- Source:
- Colloids and surfaces 2019 v.175 pp. 343-350
- ISSN:
- 0927-7765
- Subject:
- DNA; atomic force microscopy; biosensors; blood serum; colloids; electrochemistry; electrodes; electronic equipment; gold; humans; myocardial infarction; nanogold; polyacrylamide gel electrophoresis; scanning electron microscopy; signal transduction; troponin I
- Abstract:
- ... Acute myocardial infarction (AMI) is one of the most serious diseases affecting human beings. In this study, in order to rapidly detect AMI disease, the authors fabricated a label-free electrochemical biosensor composed of a multi-functional DNA structure on Au nanospike (AuNS) with a fabricated Au micro-gap electrode which was incorporated with a PCB chip in order to detect cardiac troponin I (cT ...
- DOI:
- 10.1016/j.colsurfb.2018.11.078
-
https://dx.doi.org/10.1016/j.colsurfb.2018.11.078
- Author:
- Fang, Bi-Yun; An, Jie; Liu, Bo; Zhao, Yuan-Di
- Source:
- Colloids and surfaces 2019 v.175 pp. 358-364
- ISSN:
- 0927-7765
- Subject:
- DNA; blood serum; colloids; fluorescence; fluorescent dyes; hybridization probes; nanoparticles; nanosilver; neoplasms; nucleic acid hybridization; nucleotide sequences; oligonucleotides; pH; prostate-specific antigen; proteins; salt concentration
- Abstract:
- ... In this work, a label-free Ag nanocluster (AgNC)-based fluorescent probe is proposed to detect tumor marker, prostate-specific antigen (PSA). In the experiments, DNA sequences containing segments complemented to different parts of PSA aptamer were used to synthesize DNA-Ag nanoclusters (DNA-AgNC). Some of the obtained specific DNA-AgNC exhibited significant fluorescence increase after hybridizatio ...
- DOI:
- 10.1016/j.colsurfb.2018.12.013
-
https://dx.doi.org/10.1016/j.colsurfb.2018.12.013
- Author:
- Samimi, Amir Saeed; Karimiafshar, Marzieh; Samimi, Kamyab
- Source:
- Small ruminant research 2019 v.175 pp. 78-82
- ISSN:
- 0921-4488
- Subject:
- Camelus dromedarius; Escherichia coli; acute phase proteins; amyloid; anti-inflammatory activity; antioxidants; biomarkers; blood serum; calves; flunixin; glutathione peroxidase; haptoglobins; heart rate; hematocrit; inflammation; intravenous injection; leukocytes; lipopolysaccharides; males; pentoxifylline; phenol; polymyxin B; respiratory rate; serotypes; superoxide dismutase; temperature; troponin I
- Abstract:
- ... The present study aims to 1- assessment of acute phase proteins, antioxidants and cardiovascular biomarkers during inflammatory response which was induced by Escherichia coli (E. coli) lipopolysaccharide (LPS) in dromedary calves and 2- comparatively evaluate the anti-inflammatory effects of intravenous (IV) pentoxifylline, polymyxin B, tyloxapol and flunixin thereafter. A total of thirty male dro ...
- DOI:
- 10.1016/j.smallrumres.2019.04.010
-
https://dx.doi.org/10.1016/j.smallrumres.2019.04.010
- Author:
- Wang, Yuan; Meng, Ziqi; Guo, Junqing; Wang, Wenwen; Duan, Yuanxiao; Hao, Xiran; Wang, Ruifang; An, Xiaoping; Qi, Jingwei
- Source:
- Small ruminant research 2019 v.175 pp. 65-71
- ISSN:
- 0921-4488
- Subject:
- Dorper; ammonium nitrogen; antioxidant activity; antioxidant enzymes; average daily gain; blood serum; body weight; catalase; crossbreds; crude protein; diet; digestibility; enzyme activity; esterification; feed conversion; glutathione; glutathione peroxidase; growth performance; lambs; males; metabolites; neutral detergent fiber; oligosaccharides; organic matter; pH; rumen fermentation; serum albumin; spectral analysis; superoxide dismutase; volatile fatty acids; wheat bran
- Abstract:
- ... The objective of this experiment was to investigate the effects of wheat bran feruloyl oligosaccharides (FOs) as an antioxidant supplement on performance, blood metabolites, antioxidant status and ruminal fermentation of lambs. Fifty, two-month-old crossbred male lambs (Dorper × Small-tail Han Sheep) with an initial body weight (BW) of 20.21 ± 3.36 kg were randomly assigned into five groups of ten ...
- DOI:
- 10.1016/j.smallrumres.2019.04.006
-
https://dx.doi.org/10.1016/j.smallrumres.2019.04.006
- Author:
- Wang, Ziyu; Wang, Ruocheng; Meng, Chunhua; Ji, Yu; Sun, Lingwei; Nie, Haitao; Mao, Dagan; Wang, Feng
- Source:
- Small ruminant research 2019 v.175 pp. 142-148
- ISSN:
- 0921-4488
- Subject:
- Boer (goat breed); Capra hircus; ammonia; arginine; average daily gain; blood serum; body weight; citrulline; dry matter intake; essential amino acids; goats; growth performance; insulin; jejunum; lactation; males; milk; milk proteins; milk yield; neonates; nitric oxide; ornithine; putrescine; river deltas; rumen; suckling; urea; villi
- Abstract:
- ... Arginine is one of the conditional essential amino acids for immature mammals. The deficiency of arginine in the diet may constrain growth and development of newborn kidlets through affecting the milk performance of lactating goats. In our present study, lactating crossbred of Boer goat (Capra hircus) and Yangtse River Delta White (Haimen) goat with twin male suckling kidlets were used to investig ...
- DOI:
- 10.1016/j.smallrumres.2019.01.008
-
https://dx.doi.org/10.1016/j.smallrumres.2019.01.008
- Author:
- Paiva, F.A.; Netto, A. Saran; Corrêa, L.B.; Silva, T.H.; Guimarães, I.C.S.B.; Del Claro, G.R.; Cunha, J.A.; Zanetti, M.A.
- Source:
- Small ruminant research 2019 v.175 pp. 57-64
- ISSN:
- 0921-4488
- Subject:
- blood serum; data analysis; dietary supplements; enzyme activity; excretion; feces; glutathione peroxidase; intestinal absorption; lambs; liver; males; muscle tissues; muscles; selenium; sodium selenite; total mixed rations; urine
- Abstract:
- ... The objective was to evaluate the selenium (Se) balance and Se concentration in serum, muscle and viscera as well hepatic glutathione peroxidase activity (GSH-Px) in lambs fed diets supplemented with different Se sources and levels. Forty male Suffolk lambs 90 ± 2.5 days old (19.8 ± 2.1 kg) received, during a 84 days period, a total mixed ration (TMR) with three Se sources [Sodium selenite (Na sel ...
- DOI:
- 10.1016/j.smallrumres.2019.04.008
-
https://dx.doi.org/10.1016/j.smallrumres.2019.04.008
- Author:
- Park, Sung Kyun; Peng, Qing; Ding, Ning; Mukherjee, Bhramar; Harlow, Siobán D.
- Source:
- Environmental research 2019 v.175 pp. 186-199
- ISSN:
- 0013-9351
- Subject:
- Blacks; French fries; Japanese people; Whites; acetic acid; alcohol drinking; blood serum; body mass index; drinking water; education; fish consumption; food contamination; geographical variation; hemorrhage; menstruation; minorities (people); perfluorononanoic acid; perfluorooctane sulfonic acid; perfluorooctanoic acid; pizza; popcorn; public health; regression analysis; smoking (habit); snacks; women; women's health; Michigan
- Abstract:
- ... Per- and poly-fluoroalkyl substances (PFAS) are public health concerns because of widespread exposure through contaminated foods/drinking water. Although some determinants of PFAS exposure have been suggested, the role of geographic location and race/ethnicity in PFAS exposure has not been well characterized.We examined potential determinants of PFAS from the Study of Women's Health Across the Nat ...
- DOI:
- 10.1016/j.envres.2019.05.028
- PubMed:
- 31129528
- PubMed Central:
- PMC6579633
-
https://dx.doi.org/10.1016/j.envres.2019.05.028