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1. Recombinant Newcastle disease virus (NDV) La Sota expressing the haemagglutinin–neuraminidase protein of genotype VII NDV shows improved protection efficacy against NDV challenge

Author:
Bu, Ya-wen; Yang, Hui-ming; Jin, Ji-hui; Zhao, Jing; Xue, Jia; Zhang, Guo-zhong
Source:
Avian pathology 2019 v.48 no.2 pp. 91-97
ISSN:
1465-3338
Subject:
chickens; Newcastle disease; specific pathogen-free animals; chicken eggs; morbidity; vaccines; Avian orthoavulavirus 1; viruses; genotype; reverse genetics; vaccination; death; virulence; mortality
Abstract:
... Intensive vaccination strategies against Newcastle disease (ND) have been implemented in many countries for a long time, but ND outbreaks still occur frequently, with most isolates belonging to genotype VII of Newcastle disease virus (NDV). Many researchers have revealed that vaccines closely matched to epidemic viruses provide better protection. Therefore, using a previously established reverse g ...
DOI:
10.1080/03079457.2018.1548754