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You searched for: Publication year rev 7981-2019 Remove constraint Publication year rev: 7981-2019 Subject Enterobacteriaceae Remove constraint Subject: Enterobacteriaceae Subject term minimum inhibitory concentration Remove constraint Subject term: minimum inhibitory concentration
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1. Antibacterial effect of Juniperus communis and Satureja montana essential oils against Listeria monocytogenes in vitro and in wine marinated beef

Author:
Bojana Vasilijević; Dragana Mitić-Ćulafić; Ilija Djekic; Tatjana Marković; Jelena Knežević-Vukčević; Igor Tomasevic; Branko Velebit; Biljana Nikolić
Source:
Food control 2019 v.100 pp. 247-256
ISSN:
0956-7135
Subject:
Enterobacteriaceae; Juniperus communis; Listeria monocytogenes; Satureja montana; antibacterial properties; beef; beef carcasses; essential oils; lactic acid bacteria; marinating; mesophyll; minimum inhibitory concentration; red wines; synergism
Abstract:
... Juniperus communis and Satureja montana essential oils (EOs) were chemically characterized and their activity against Listeria monocytogenes was evaluated. Antilisterial effect was determined in vitro and in situ, in red wine-marinated beef, where the effect against common meat contaminants (aerobic heterotrophic mesophyll bacteria, Enterobacteriaceae and lactic acid bacteria) was also monitored.M ...
DOI:
10.1016/j.foodcont.2019.01.025

2. Breakpoint to MIC quotient: A parameter to rapidly evaluate the in vitro bactericidal activity of β-lactams on Enterobacteriaceae

Author:
Antoine Grillon; Angeline Chabaud; Gilles Zambardi; Isabelle Caniaux; François Jehl
Source:
International journal of antimicrobial agents 2019 v.53 no.5 pp. 674-677
ISSN:
0924-8579
Subject:
Enterobacteriaceae; antibacterial properties; antibiotic resistance; antibiotics; bacterial infections; beta-lactams; minimum inhibitory concentration; pathogens; patients; risk
Abstract:
... Minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) do not completely predict the bactericidal nature of the antimicrobial agent. Patients with pathogens having MICs near the clinical breakpoint experience a higher risk of clinical failure. This study defined an indicator, breakpoint to MIC quotient (BMQ), that incorporates MIC and the European Committee on Antimicr ...
DOI:
10.1016/j.ijantimicag.2019.01.013

3. Evaluation of the BD Phoenix automated system for determining antimicrobial susceptibility against carbapenem-resistant Enterobacteriaceae compared with broth microdilution

Author:
Zachary J. Haffler; Brandon Kulengowski; Julie A. Ribes; David S. Burgess
Source:
International journal of antimicrobial agents 2019 v.54 no.2 pp. 249-254
ISSN:
0924-8579
Subject:
Enterobacteriaceae; amikacin; antibiotic resistance; automation; aztreonam; ceftazidime; ertapenem; gentamicin; health services; levofloxacin; meropenem; minimum inhibitory concentration; mortality; nitrofurantoin; tobramycin
Abstract:
... Carbapenem-resistant Enterobacteriaceae (CRE) are increasingly widespread in the healthcare system, resulting in infections associated with mortality of up to 50%. Many laboratories use automated systems to identify CRE isolates and determine susceptibility. The aim of this study was to evaluate categorical agreement between the BD Phoenix automated system and the gold standard – broth microdiluti ...
DOI:
10.1016/j.ijantimicag.2019.05.002

4. In Vitro Activity of Cefiderocol, a Siderophore Cephalosporin, Against Gram-Negative Bacilli Isolated by Clinical Laboratories in North America and Europe in 2015-2016: SIDERO-WT-2015

Author:
James A. Karlowsky; Meredith A. Hackel; Masakatsu Tsuji; Yoshinori Yamano; Roger Echols; Daniel F. Sahm
Source:
International journal of antimicrobial agents 2019 v.53 no.4 pp. 456-466
ISSN:
0924-8579
Subject:
Acinetobacter; Burkholderia cepacia; Enterobacteriaceae; Gram-negative bacteria; Pseudomonas aeruginosa; Stenotrophomonas maltophilia; cephalosporins; minimum inhibitory concentration; siderophores; Europe; North America
Abstract:
... Cefiderocol (S-649266) is a parenteral siderophore cephalosporin in phase III of clinical development. In this study, we determined the in vitro susceptibility to cefiderocol and comparators of a 2015-2016 collection of 8954 clinical isolates of Gram-negative bacilli (GNB), provided by 100 clinical laboratories in North America and Europe, using the Clinical and Laboratory Standards Institute brot ...
DOI:
10.1016/j.ijantimicag.2018.11.007

5. In vitro potentiation of carbapenems with tannic acid against carbapenemase‐producing enterobacteriaceae: exploring natural products as potential carbapenemase inhibitors

Author:
A.M. Somboro; J. Osei Sekyere; D.G. Amoako; H.M. Kumalo; R. Khan; L.A. Bester; S.Y. Essack
Source:
Journal of applied microbiology 2019 v.126 no.2 pp. 452-467
ISSN:
1364-5072
Subject:
Enterobacteriaceae; active sites; adjuvants; beta-lactamase; binding capacity; carbapenems; cytotoxicity; enzyme inhibition; enzyme inhibitors; hydrophobicity; inhibitory concentration 50; minimum inhibitory concentration; tannins; transporters
Abstract:
... AIMS: We hypothesized and confirmed that tannic acid (TA) reverses carbapenem resistance by inhibiting carbapenemases in class A and B carbapenemase‐producing Enterobacteriaceae. METHODS AND RESULTS: Minimum inhibitory concentrations of carbapenems in the presence and absence of TA and other efflux pump inhibitors, TA‐carbapenemases inhibition assays and computational studies showed that TA had th ...
DOI:
10.1111/jam.14141

6. Significant role of Asn-247 and Arg-64 residues in close proximity of the active site in maintaining the catalytic function of CTX-M-15 type β-lactamase

Author:
Lubna Maryam; Shamsi Khalid; Abid Ali; Asad U. Khan
Source:
RSC advances 2019 v.9 no.10 pp. 5325-5337
ISSN:
2046-2069
Subject:
Enterobacteriaceae; active sites; antibiotic resistance; arginine; asparagine; bacterial infections; beta-lactamase; cefotaxime; circular dichroism spectroscopy; fluorescence; hydrolysis; minimum inhibitory concentration; mutants; polymerase chain reaction; proteins; site-directed mutagenesis; spectral analysis
Abstract:
... Members of Enterobacteriaceae cause antibiotic-resistant infections worldwide. One such marker, CTX-M-15, expressed by Enterobacteriaceae produces β-lactamases, which hydrolyze the cephalosporin group of antibiotics, such as cefotaxime, used in the treatment of both Gram-positive and negative bacterial infections. Amino acid residues present in close proximity of the active site might also play a ...
DOI:
10.1039/c8ra10313e

7. Urinary piperacillin/tazobactam pharmacokinetics in vitro to determine the pharmacodynamic breakpoint for resistant Enterobacteriaceae

Author:
M. Gould; A.N. Ginn; D. Marriott; R. Norris; I. Sandaradura
Source:
International journal of antimicrobial agents 2019 v.54 no.2 pp. 240-244
ISSN:
0924-8579
Subject:
Enterobacteriaceae; beta-lactamase; minimum inhibitory concentration; multiple drug resistance; pharmacodynamics; pharmacokinetics; piperacillin; regression analysis; resistance mechanisms; simulation models; urinary tract diseases; urine
Abstract:
... Urinary tract infections caused by multidrug-resistant Enterobacteriaceae are a growing burden worldwide. Recent studies of urinary pharmacokinetics described high piperacillin/tazobactam (TZP) concentrations in urine, but it is unknown whether this results in treatment efficacy. This study investigated the pharmacodynamics of TZP in a static in vitro model for Enterobacteriaceae to determine the ...
DOI:
10.1016/j.ijantimicag.2019.05.013