Jump to Main Content
- Wang, Huai-Sheng, et al. Show all 8 Authors
- Biosensors & bioelectronics 2019 v.144 pp. 111669
- DNA; aptasensors; disease diagnosis; electrochemiluminescence; electrodes; enzymes; gold; magnetism; oligonucleotides; urine
- ... 8-Hydroxy-2′-deoxyguanosine (8-OH-dG) is a principal stable marker of DNA oxidative damage. Sensitive and specific detection of 8-OH-dG is of great importance for early disease diagnosis. In this paper, we developed an electrochemiluminescence aptasensor for 8-OH-dG detection based on target induced multi-DNA release and nicking enzyme signaling amplification strategy. First, three kinds of short ...