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You searched for: Publication year rev 7981-2019 Remove constraint Publication year rev: 7981-2019 Subject term Danio rerio Remove constraint Subject term: Danio rerio
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1. 1,3‐1‐6 ß‐glucans enhance tissue regeneration in zebrafish (Danio rerio): Potential advantages for aquaculture applications

Author:
Baldassare Fronte; Cheol‐Hee Kim; Marco Bagliacca; Lucia Casini; Mahanama De Zoysa
Source:
Aquaculture research 2019 v.50 no.11 pp. 3163-3170
ISSN:
1355-557X
Subject:
Danio rerio; amputation; animal models; aquaculture; beta-glucans; diet; fish; gills; macrophages; oral administration; secondary infection; stocking rate; tissue repair; tissues
Abstract:
... High aquacultural rearing density and handling of fish may frequently result in skin or gills wounds, thereby facilitating the onset of secondary infections. The capacity of the zebrafish to regenerate tissues, as well as fins and other organs, makes it an ideal animal model for studying the mechanisms of tissue regeneration. Since macrophages are involved in tissue regeneration, a diet including ...
DOI:
10.1111/are.14270

2. 2,4-Dichlorophenoxyacetic acid containing herbicide impairs essential visually guided behaviors of larval fish

Author:
Gavin K. Dehnert; William H. Karasov; Marc A. Wolman
Source:
Aquatic toxicology 2019 v.209 pp. 1-12
ISSN:
0166-445X
Subject:
2,4-D; Danio rerio; Perca flavescens; active ingredients; auxins; cell death; ecosystems; fish communities; fish larvae; freshwater fish; invasive species; nervous system; neural networks; nontarget organisms; plants (botany); spawning; toxicity; vision; xenobiotics
Abstract:
... Aquatic herbicides are used worldwide to eradicate nuisance and invasive plants despite limited knowledge of their toxicity to non-target organisms. 2,4-Dichlorophenoxyacetic acid (2,4-D) is a common active ingredient in commercial herbicide formulations, which triggers plant cell death by mimicking the plant-specific hormone auxin. Application practices of 2,4-D commercial herbicides typically co ...
DOI:
10.1016/j.aquatox.2019.01.015

3. 3D light-sheet assay assessing novel valproate-associated cardiotoxicity and folic acid relief in zebrafish embryogenesis

Author:
Seoyoung Ki; Seung-Hae Kwon; Juneyong Eum; Ahmed A. Raslan; Kil-Nam Kim; Byung Joon Hwang; Yun Kee
Source:
Chemosphere 2019 v.227 pp. 551-560
ISSN:
0045-6535
Subject:
Danio rerio; cardiomyocytes; cardiotoxicity; embryo (animal); embryogenesis; folic acid; heart rate; image analysis; microscopy; models; phenotype; quantitative analysis; risk; valproic acid; wastes
Abstract:
... Precise in vivo toxicological assays to determine the cardiotoxicity of pharmaceuticals and their waste products are essential in order to evaluate their risks to humans and the environment following industrial release. In the present study, we aimed to develop the sensitive imaging-based cardiotoxicity assay and combined 3D light-sheet microscopy with a zebrafish model to identify hidden cardiova ...
DOI:
10.1016/j.chemosphere.2019.04.061

4. Caenorhabditis elegans Infrared-Based Motility Assay Identified New Hits for Nematicide Drug Development

Author:
Gastón Risi; Elena Aguilera; Enrique Ladós; Gonzalo Suárez; Inés Carrera; Guzmán Álvarez; Gustavo Salinas
Source:
Veterinary sciences 2019 v.6 no.1 pp. -
ISSN:
2306-7381
Subject:
Caenorhabditis elegans; Danio rerio; Haemonchus contortus; active ingredients; animal models; aromatic compounds; automation; drug development; drugs; free-living nematodes; hydrazine; ketones; livestock; nematicides; parasites; screening; vertebrates
Abstract:
... Nematode parasites have a profound impact on humankind, infecting nearly one-quarter of the world’s population, as well as livestock. There is a pressing need for discovering nematicides due to the spread of resistance to currently used drugs. The free-living nematode Caenorhabditis elegans is a formidable experimentally tractable model organism that offers key advantages in accelerating nem ...
DOI:
10.3390/vetsci6010029
PubMed:
30884899
PubMed Central:
PMC6466232

5. A Cold-Sensing Receptor Encoded by a Glutamate Receptor Gene

Author:
Jianke Gong; Jinzhi Liu; Elizabeth A. Ronan; Feiteng He; Wei Cai; Mahar Fatima; Wenyuan Zhang; Hankyu Lee; Zhaoyu Li; Gun-Ho Kim; Kevin P. Pipe; Bo Duan; Jianfeng Liu; X.Z. Shawn Xu
Source:
Cell 2019 v.178 no.6 pp. 1375-1386.e11
ISSN:
0092-8674
Subject:
Danio rerio; G-proteins; alleles; cold; glutamate receptors; mice; mutants; sensory neurons; temperature
Abstract:
... In search of the molecular identities of cold-sensing receptors, we carried out an unbiased genetic screen for cold-sensing mutants in C. elegans and isolated a mutant allele of glr-3 gene that encodes a kainate-type glutamate receptor. While glutamate receptors are best known to transmit chemical synaptic signals in the CNS, we show that GLR-3 senses cold in the peripheral sensory neuron ASER to ...
DOI:
10.1016/j.cell.2019.07.034
PubMed:
31474366
PubMed Central:
PMC6743979

6. A Critical Review of Animal Models Used in Acute Myeloid Leukemia Pathophysiology

Author:
Hala Skayneh; Batoul Jishi; Rita Hleihel; Maguy Hamieh; Nadine Darwiche; Ali Bazarbachi; Marwan El Sabban; Hiba El Hajj
Source:
Genes 2019 v.10 no.8 pp. -
ISSN:
2073-4425
Subject:
Danio rerio; Drosophila; animal models; cytogenetics; disease progression; epigenetics; mice; mutation; myeloid leukemia; pathophysiology; prognosis; rats; survival rate; therapeutics; toxicity
Abstract:
... Acute myeloid leukemia (AML) is one of the most frequent, complex, and heterogeneous hematological malignancies. AML prognosis largely depends on acquired cytogenetic, epigenetic, and molecular abnormalities. Despite the improvement in understanding the biology of AML, survival rates remain quite low. Animal models offer a valuable tool to recapitulate different AML subtypes, and to assess the pot ...
DOI:
10.3390/genes10080614
PubMed:
31412687
PubMed Central:
PMC6722578

7. A Mitochondrial-Targeting Near-Infrared Fluorescent Probe for Visualizing and Monitoring Viscosity in Live Cells and Tissues

Author:
Yuying Zhang; Zhen Li; Wei Hu; Zhihong Liu
Source:
Analytical chemistry 2019 v.91 no.15 pp. 10302-10309
ISSN:
1520-6882
Subject:
Danio rerio; fluorescence; fluorescent dyes; human cell lines; ionophores; liver; metabolism; metabolites; mitochondria; mitophagy; monitoring; quinoline; tissues; viscosity
Abstract:
... The intracellular viscosity is closely related to many functional disorders and diseases. Especially, abnormal mitochondrial viscosity changes are one of the distinct indications in metabolite diffusion as well as mitochondrial metabolism. In this work, we report a novel fluorescent probe (NI-VIS), which uses quinoline as an acceptor group and employs a TICT mechanism (twisted intramolecular charg ...
DOI:
10.1021/acs.analchem.9b02678

8. A Near-infrared Persistent Luminescence Imaging Technique for Tracking Nanoparticles in Zebrafish (Danio rerio)

Author:
Chengcheng Wang; Shenghui Zheng; Xiaoyan Zou; Xia Sun; Hongwu Zhang
Source:
Bulletin of environmental contamination and toxicology 2019 v.103 no.2 pp. 267-273
ISSN:
0007-4861
Subject:
Danio rerio; abdomen; animal models; excretion; gills; image analysis; intestines; luminescence; metabolism; monitoring; nanoparticles; risk; vertebrates
Abstract:
... The development of nanotechnology has drawn increased attention to the risks of nanoparticles (NPs). In this work, the near-infrared persistent luminescence imaging technique was used to track the biodistribution of NPs in vivo in zebrafish. Zebrafish were used as a vertebrate animal model to show NPs distribution and the effects of exposure. ZnGa₂O₄:Cr (ZGOC) was chosen as the probe in this work. ...
DOI:
10.1007/s00128-019-02642-w

9. A PET and ESIPT based fluorescent probe for the imaging of hydrogen sulfide (H₂S) in live cells and zebrafish

Author:
Yaru Lu; Baoli Dong; Wenhui Song; Xiuqi Kong; Abdul Hadi Mehmood; Weiying Lin
Source:
Analytical methods 2019 v.11 no.26 pp. 3301-3306
ISSN:
1759-9679
Subject:
Danio rerio; analytical methods; fluorescence; fluorescent dyes; hydrogen sulfide; image analysis; rapid methods; thiolysis
Abstract:
... H₂S is an important signaling molecule in living systems and participates in a series of physiological and pathological processes. In situ and rapid detection of H₂S levels in living systems is of great importance to the in-depth study of its physiological and pathological roles. Herein, we present a new fluorescent probe (DFAN) for the detection of H₂S in live cells and zebrafish. The probe DFAN ...
DOI:
10.1039/c9ay00927b

10. A Unique Approach to Development of a Multiratiometric Fluorescent Composite Probe for Multichannel Bioimaging

Author:
Guanghan Li; Yanyan Ma; Meishan Pei; Weiying Lin
Source:
Analytical chemistry 2019 v.91 no.22 pp. 14586-14590
ISSN:
1520-6882
Subject:
Danio rerio; bioimaging; fluorescence; fluorescent dyes; sulfur dioxide
Abstract:
... Ratiometric fluorescent probes have shown great potential for optical sensing and have been widely used for bioimaging. However, due to extremely stringent molecular design, most conventional organic ratiometric fluorescent probes can only achieve one single ratio. Currently, the detection of a target in living systems in a multiratiometric manner is prominently challenging. Therefore, it is of gr ...
DOI:
10.1021/acs.analchem.9b03653

11. A Zebrafish Model for Selenoprotein Synthesis and Function (OR11-01-19)

Author:
Paul Copeland; Michael Vetick
Source:
Current developments in nutrition 2019 v.3 no.Supplement_1 pp. -
ISSN:
2475-2991
Subject:
CRISPR-Cas systems; Danio rerio; RNA-binding proteins; animal models; codons; death; enzymes; fish; gene editing; homozygosity; hydrogen peroxide; messenger RNA; molecular weight; mutants; oxidative stress; phenotype; protein synthesis; selenium; selenocysteine; selenoproteins
Abstract:
... We have established a zebrafish model system that will allow unprecedented access to the role of selenoprotein function during development. The work described here focuses on a poorly characterized RNA binding protein that is similar to SECIS binding protein 2 (SBP2), which is required for the co-translational insertion of selenocysteine at select UGA codons in selenoprotein mRNAs. This protein, S ...
DOI:
10.1093/cdn/nzz044.OR11-01-19

12. A chromenoquinoline-based two-photon fluorescent probe for the highly specific and fast visualization of sulfur dioxide derivatives in living cells and zebrafish

Author:
Fangyuan Cai; Bo Hou; Shuping Zhang; Hua Chen; Shichen Ji; Xing-can Shen; Hong Liang
Source:
Journal of materials chemistry B 2019 v.7 no.15 pp. 2493-2498
ISSN:
2050-7518
Subject:
Danio rerio; bisulfites; fluorescent dyes; image analysis; moieties; monitoring; sulfites; sulfur dioxide
Abstract:
... Sulfur dioxide (SO₂) derivatives play critical roles in various biological processes. Therefore, effective methods for monitoring SO₂ are of vital importance in bisulfite/sulfite biology. In this study, a two-photon (TP) imaging probe (CQ-SO₂) for detecting SO₂ derivatives was designed and constructed, based on the chromenoquinoline (CQ) fluorophore and a β-chlorovinyl aldehyde sensing moiety. The ...
DOI:
10.1039/c9tb00179d

13. A fast-responsive two-photon fluorescent probe for monitoring endogenous HClO with a large turn-on signal and its application in zebrafish imaging

Author:
Jian-Yong Wang; Jianbo Qu; Haitao Zhang; Kang Wei; Shan-Xiu Ni
Source:
RSC advances 2019 v.9 no.29 pp. 16467-16471
ISSN:
2046-2069
Subject:
Danio rerio; fluorescent dyes; image analysis; monitoring; tissues
Abstract:
... A novel fast-responsive two-photon fluorescent probe NS-ClO was constructed for imaging endogenous HClO in living cells, tissues and fresh zebrafish with a large turn-on signal (about 860 times) and Stokes shift (about 90 nm). The probe NS-ClO for the recognition of HClO in vivo exhibited fast response (about 1 min) and good selectivity; thus, it might be a useful tool to understand the role of HC ...
DOI:
10.1039/c9ra02160d

14. A flexible-imprinted capacitive sensor for rapid detection of adrenaline

Author:
Dhanjai; Nancy Yu; Samuel M. Mugo
Source:
Talanta 2019 v.204 pp. 602-606
ISSN:
0039-9140
Subject:
Danio rerio; aniline; biomimetics; biosensors; brain; carbon; detection limit; epinephrine; moieties; monitoring; nanocrystals; nanosheets; phenylboronic acids; polydimethylsiloxane; rapid methods
Abstract:
... This article demonstrates a non-enzymatic biomimetic adrenaline capacitive sensor fabricated inexpensively by layer-by-layer (LbL) assembly. The LbL assembly consists of polydimethylsiloxane (PDMS) substrate, carbon nanotube-cellulose nanocrystals (CNC/CNT) nanofilms (first layer) with adrenaline imprinted poly (aniline/phenylboronic acid) (pANI/PBA) moieties (second layer). The flexible sensor ha ...
DOI:
10.1016/j.talanta.2019.06.016

15. A fructooligosaccharide from Achyranthes bidentata inhibits osteoporosis by stimulating bone formation

Author:
Chunyan Yan; Shaojie Zhang; Changsheng Wang; Qian Zhang
Source:
Carbohydrate polymers 2019 v.210 pp. 110-118
ISSN:
0144-8617
Subject:
Achyranthes japonica; Danio rerio; adverse effects; bone density; bone formation; fluorescence; fructans; fructooligosaccharides; ingredients; medicinal plants; models; nuclear magnetic resonance spectroscopy; osteoporosis; ovariectomy; rats
Abstract:
... Achyranthes bidentata is used as a medicinal herb prescribed for the treatment of osteoporosis in China. The anti-osteoporosis activity of the crude polysaccharide from A. bidentata, AB50, was evaluated by ovariectomized rats. The results indicated that AB50 has prominent osteoprotective effects, which was comparable to positive control. To further explore which ingredients are responsible for the ...
DOI:
10.1016/j.carbpol.2019.01.026

16. A highly specific fluorescent probe for rapid detection of hypochlorous acid in vivo and in water samples

Author:
Huan FengThese authors contributed equally to this work and they should be regarded as co-first authors.; Yue Wang; Jianping Liu; Zhiqiang Zhang; Xinyi Yang; Rong Chen; Qingtao Meng; Run Zhang
Source:
Journal of materials chemistry B 2019 v.7 no.24 pp. 3909-3916
ISSN:
2050-7518
Subject:
Danio rerio; adults; chemistry; colorimetry; cytotoxicity; detection limit; fluorescence; fluorescent dyes; human health; image analysis; mice; rapid methods
Abstract:
... Hypochlorous acid (HOCl) is closely related to human health and is widely used in our daily lives. Accordingly, detection of HOCl in live organisms and natural water samples is significantly important to human and animal health. In this paper, a novel chromogenic and fluorogenic probe (PI) was prepared for HOCl detection with high sensitivity and specificity. PI exhibits weak fluorescence emission ...
DOI:
10.1039/c9tb00551j

17. A holistic study on potential toxic effects of carboxylated multi-walled carbon nanotubes (MWCNTs-COOH) on zebrafish (Danio rerio) embryos/larvae

Author:
Feyza Icoglu Aksakal; Abdulkadir Ciltas; Nihal Simsek Ozek
Source:
Chemosphere 2019 v.225 pp. 820-828
ISSN:
0045-6535
Subject:
Danio rerio; Raman spectroscopy; abnormal development; antioxidants; carbon nanotubes; carboxylation; edema; gene expression; genes; hatching; head; heart rate; immune system; innate immunity; interleukin-1beta; larvae; mortality; oxidative stress; pericardium; physicochemical properties; products and commodities; tail; toxicity; yolk sac
Abstract:
... Multi-walled carbon nanotubes (MWCNTs) have widespread use in industrial and consumer products and great potential in biomedical applications. This leads to inevitably their release into the environment and the formation of their toxic effects on organisms. These effects can change depending on their physicochemical characteristics. Therefore, the toxicological findings of MWCNTs are inconsistent. ...
DOI:
10.1016/j.chemosphere.2019.03.083

18. A marine sponge associated fungal metabolite monacolin X suppresses angiogenesis by down regulating VEGFR2 signaling

Author:
Sirpu Natesh Nagabhishek; Arumugam Madan Kumar; Sambhavi B.; Anandan Balakrishnan; Yash T. Katakia; Suvro Chatterjee; Nagarajan Nagasundaram
Source:
RSC advances 2019 v.9 no.46 pp. 26646-26667
ISSN:
2046-2069
Subject:
Danio rerio; Porifera; active sites; amino acids; angiogenesis; breast neoplasms; embryo (animal); fungi; gene expression; gene expression regulation; messenger RNA; monacolins; protein kinase C; protein synthesis; rats; remission; vascular endothelial growth factor receptor-2; vascular endothelial growth factors
Abstract:
... Cancer is one of the leading causes of global death and there is an urgent need for the development of cancer treatment; targeting VEGFR2 could be one of the promising therapies. In the present study, previously isolated marine fungal metabolite monacolin X, suppresses in vitro angiogenic characteristics such as proliferation, migration, adhesion, invasion and tube formation of HUVECs when stimula ...
DOI:
10.1039/c9ra05262c

19. A mitochondria-targeted fluorescent probe based on coumarin–pyridine derivatives for hypochlorite imaging in living cells and zebrafish

Author:
Xiuli Zhong; Qing Yang; Yingshuang Chen; Yuliang Jiang; Bingxiang Wang; Jian Shen
Source:
Journal of materials chemistry B 2019 v.7 no.46 pp. 7332-7337
ISSN:
2050-7518
Subject:
Danio rerio; chemistry; detection limit; fluorescent dyes; hypochlorites; image analysis; mitochondria; monitoring
Abstract:
... Hypochlorite plays a critical role in various physiological processes and is involved in many diseases. Thus, real-time, rapid, and accurate monitoring of hypochlorite has important medical and physiological significance. Herein, a novel coumarin–pyridine derivative (CPD) probe was designed and synthesized, which exhibited fantastic advantages, such as a rapid response (within 10 s), naked eye rec ...
DOI:
10.1039/c9tb01948k

20. A mitochondria-targeted two-photon fluorogenic probe for the dual-imaging of viscosity and H₂O₂ levels in Parkinson's disease models

Author:
Hao LiThese authors contributed equally to this work.; Chenqi Xin; Gaobin Zhang; Xisi Han; Wenjing Qin; Cheng-wu Zhang; Changmin Yu; Su Jing; Lin Li; Wei Huang
Source:
Journal of materials chemistry B 2019 v.7 no.27 pp. 4243-4251
ISSN:
2050-7518
Subject:
Danio rerio; Drosophila; Parkinson disease; chemistry; confocal microscopy; disease models; fluorescent dyes; hydrogen peroxide; mitochondria; pathogenesis; patients; quality of life; viscosity
Abstract:
... Parkinson's disease (PD) is a neurodegenerative disease that seriously affects the quality of life of the patient. Many sources have shown that mitochondrial dysfunction is increasingly appreciated as playing a critical role in the pathogenesis of PD. The mitochondrial microenvironment and H₂O₂ level are two key parameters that are used to assess the function of mitochondria. Herein, we designed a ...
DOI:
10.1039/c9tb00576e