Publication year rev: 7981-2019 / Subject term: 3 selected / Text availability: Citation in PubAg

Author:: Cheng-Yao MA; Jia-Hui LU; Xiang LI; Xiao LIU; Jian-Wei CHEN
Source:: Chinese journal of natural medicines 2019 v.17 no.4 pp. 291-297
ISSN:: 1875-5364
Subject:: Annona squamosa; Oriental traditional medicine; acetogenins; cell lines; cytotoxicity; multiple drug resistance; seeds; spectral analysis
Abstract:: ... Eight new annonaceous acetogenins, squamotin A-D (1–4), annosquatin IV-V (5 and 6), muricin O (7) and squamosten B (8), together with four known ones (9–12) were isolated from the seeds of Annona squamosa. Their structures were elucidated by chemical methods and spectral data. The inhibitory activities of compound 1–9 against three multidrug resistance cell lines were evaluated. All tested compoun ...
DOI:: 10.1016/S1875-5364(19)30032-9
: https://doi.org/10.1016/S1875-5364(19)30032-9

Author:: Zheng LI; Qian-Qian CHEN; Christopher Wai Kei LAM; Jian-Ru GUO; Wei-Jia ZHANG; Cai-Yun WANG; Vincent Kam Wai WONG; Mei-Cun YAO; Wei ZHANG
Source:: Chinese journal of natural medicines 2019 v.17 no.8 pp. 608-615
ISSN:: 1875-5364
Subject:: DNA replication; Oriental traditional medicine; adenocarcinoma; antineoplastic activity; cell cycle checkpoints; cell lines; cytotoxicity; epithelial cells; humans; hydroxyurea; interphase; liquid chromatography; lungs; mass spectrometry; metabolism; metabolomics; nucleosides; resveratrol
Abstract:: ... In an effort to understand the molecular events contributing to the cytotoxicity activity of resveratrol (RSV), we investigated its effects on human lung adenocarcinoma epithelial cell line A549 at different concentrations. Cellular nucleoside metabolic profiling was determined by an established liquid chromatography-mass spectrometry method in A549 cells. RSV resulted in significant decreases and ...
DOI:: 10.1016/S1875-5364(19)30063-9
: https://doi.org/10.1016/S1875-5364(19)30063-9

Author:: Qing Lin; Mengke Qu; Hirak K. Patra; Shanshan He; Luyao Wang; Xun Hu; Linyu Xiao; Yu Fu; Tao Gong; Qin He; Ling Zhang; Xun Sun; Zhirong Zhang
Source:: Journal of ethnopharmacology 2019 pp. -
ISSN:: 0378-8741
Subject:: Fritillaria cirrhosa; Oriental traditional medicine; Western blotting; active ingredients; adverse effects; animal models; antineoplastic activity; antineoplastic agents; blood cell counts; cancer therapy; case studies; cell lines; cytotoxicity; drug delivery systems; enzyme-linked immunosorbent assay; films (materials); herbal medicines; histopathology; immunohistochemistry; in vivo studies; inflammation; lung neoplasms; mice; transcription factor NF-kappa B
Abstract:: ... Bulbus Fritillaria cirrhosa D. Don (BFC) is a Chinese traditional herbal medicine that has long been used as an indispensable component in herbal prescriptions for bronchopulmonary diseases due to its well-established strong anti-inflammation and pulmonary harmonizing effects. Interestingly, there are few case reports in traditional Chinese medicine available where they found it to contribute in a ...
DOI:: 10.1016/j.jep.2019.112283
: https://doi.org/10.1016/j.jep.2019.112283

Author:: Ping Song; Hao Chen; Yun Huang; Yanzhang Wen; Ji Hao; Yibing Lv; Shihao Deng; Xinzhou Yang
Source:: Chemistry of natural compounds 2019 v.55 no.5 pp. 835-838
ISSN:: 0009-3130
Subject:: Oriental traditional medicine; Sophora alopecuroides; anticarcinogenic activity; cell lines; cytotoxicity; ethyl acetate; hepatoma; nuclear magnetic resonance spectroscopy; phenolic acids; seeds; spectral analysis
Abstract:: ... Chemical profiling of the EtOAc extract from a traditional Chinese medicine Sophora alopecuroides yielded a new phenolic acid, (3S,2R)-methyl 2-(4-hydroxybenzyl)tartrate (1), along with four known compounds, eucomic acid (2), methyl eucomate (3), piscidic acid (4), and ethyl 2-(4-hydroxybenzyl)tartrate (5). The structure of 1 was determined by extensive spectral analyses including 1D and 2D NMR an ...
DOI:: 10.1007/s10600-019-02826-0
: https://doi.org/10.1007/s10600-019-02826-0

Author:: Peng-Cheng LIN; Lin-Lin JI; Xiang-Jian ZHONG; Jin-Jie LI; Xin WANG; Xiao-Ya SHANG; Sheng LIN
Source:: Chinese journal of natural medicines 2019 v.17 no.1 pp. 22-26
ISSN:: 1875-5364
Subject:: Cirsium arvense; Oriental traditional medicine; animal ovaries; antineoplastic activity; cell lines; chemical structure; colorectal neoplasms; cytotoxicity; food plants; humans; inhibitory concentration 50; ovarian neoplasms; secretion; spectral analysis; triterpenoids; tumor necrosis factor-alpha
Abstract:: ... Guided by TNF-α secretion inhibitory activity assay, four taraxastane-type triterpenoids, including two new ones, 22-oxo-20-taraxasten-3β, 30-diol (1) and 22α-hydroxy-20-taraxasten-30β, 30-triol (2), have been obtained from an active fraction of the petroleum ether-soluble extract of the the medicinal and edible plant Cirsium setosum. Their structures were elucidated by spectroscopic data and CD d ...
DOI:: 10.1016/S1875-5364(19)30005-6
: https://doi.org/10.1016/S1875-5364(19)30005-6

Author:: Yi Jing; Hai-Jiang Zhang; Kui-Wu Wang; Xiao-Xin Wang; Ming-Long Chen; Hong Wang; Bin Wu
Source:: Phytochemistry letters 2019 v.29 pp. 134-137
ISSN:: 1874-3900
Subject:: Hedyotis; Oriental traditional medicine; anthraquinones; cell lines; chemotaxonomy; cytotoxicity; inhibitory concentration 50; neoplasm cells; nuclear magnetic resonance spectroscopy; physicochemical properties
Abstract:: ... Seven anthraquinones, including two new natural products, hedyanthraquinones A and B (1, 2), were isolated from Hedyotis caudatifolia. The structures were elucidated based on NMR, MS data and physico-chemical properties. Compounds 1 and 2 displayed moderate cytotoxic activities against a panel of cultured tumor cell lines (HL-60, Bcap37, SMMC7721) with IC50 values of 13.71 ∼ 26.29 μM. The result s ...
DOI:: 10.1016/j.phytol.2018.11.026
: https://doi.org/10.1016/j.phytol.2018.11.026

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