You searched for:
Publication year rev
7981-2019
Remove constraint Publication year rev: 7981-2019
Subject term
anti-inflammatory activity
Remove constraint Subject term: anti-inflammatory activity
Subject term
X-ray diffraction
Remove constraint Subject term: X-ray diffraction
PubAg
Main content area
Limit your search
Search
29 Search Results
« Previous |
1 - 20 of 29
|
Next »
Search Results
- Author:
- Bing Peng; Rui-Fei Zhang; Bing-Zhao Du; Shun-Gang Jiao; Xiao-Chun Zhou; Xiao-Li Gao; Su-Yi-Le Chen; Peng-Fei Tu; Xing-Yun Chai
- Source:
- Journal of Asian natural products research 2019 v.21 no.12 pp. 1161-1169
- ISSN:
- 1477-2213
- Subject:
- Syringa; X-ray diffraction; circular dichroism spectroscopy; cytotoxicity; human cell lines; inhibitory concentration 50; macrophages; nitric oxide; nuclear magnetic resonance spectroscopy; sesquiterpenoids; stems
- Abstract:
- ... Three new eremophilane-type sesquiterpenoids, alashanoids K–M (1–3), and one known analogue (4) were isolated from the peeled stems of Syringa pinnatifolia. All the compounds were isolated from the genus Syringa for the first time. Structures of these compounds were established using 1D and 2D NMR and MS data. The absolute configurations were determined by experimental and calculated electronic ci ...
- DOI:
- 10.1080/10286020.2019.1694516
- https://doi.org/10.1080/10286020.2019.1694516
- Author:
- Chun-Lin Fan; Yu-Bo Zhang; Ye Chen; Pei Xie; Guo-Cai Wang; Hai-Yan Tian; Yao-Lan Li; Xiao-Jun Huang; Xiao-Qi Zhang; Zhi-Yong Li; Jun-Shan Liu; Wen-Cai Ye; Wei-Min Chen
- Source:
- Journal of natural products 2019 v.82 no.12 pp. 3227-3232
- ISSN:
- 1520-6025
- Subject:
- Sophora alopecuroides; X-ray diffraction; aerial parts; alkaloids; anti-inflammatory activity; epoxides; moieties; spectroscopy
- Abstract:
- ... Five new matrine-type alkaloid dimers, alopecuroides A–E, were isolated from the aerial parts of Sophora alopecuroides. Alopecuroides A and B represent the first dimeric matrine-type alkaloids possessing a cyano group and an epoxy moiety. Alopecuroides C and D are dimeric matrine-type alkaloids connected via C-2–C-9′ and C-10–C-3′ bonds, respectively. The chemical structures of alopecuroides A–E w ...
- DOI:
- 10.1021/acs.jnatprod.8b01081
- https://doi.org/10.1021/acs.jnatprod.8b01081
- Author:
- Caio A. Campos; Bruno S. Lima; Gabriela G.G. Trindade; Eloísa P.B.S.S. Souza; Débora S.A. Mota; Luana Heimfarth; Jullyana S.S. Quintans; Lucindo J. Quintans-Júnior; Eliana M. Sussuchi; Victor H.V. Sarmento; Flávio M.S. Carvalho; Ricardo N. Marreto; Roseane M.R. Costa; Rogéria S. Nunes; Adriano A.S. Araújo; Saravanan Shanmugam; Parimelazhagan Thangaraj
- Source:
- Life sciences 2019 v.229 pp. 139-148
- ISSN:
- 0024-3205
- Subject:
- Cymbopogon citratus; Fourier transform infrared spectroscopy; X-ray diffraction; animal models; anti-inflammatory activity; beta-cyclodextrin; bioavailability; carrageenan; cell lines; cell viability; differential scanning calorimetry; differential thermal analysis; essential oils; freeze drying; geranial; high performance liquid chromatography; leukocytes; macrophages; mice; neral; pain; pleurisy; scanning electron microscopy; solubility; somatosensory disorders; stereoisomers; thermogravimetry; tumor necrosis factor-alpha; viability assays
- Abstract:
- ... Citral (CIT) is a monoterpene formed by the geranial and neral stereoisomers. CIT is the major compound of Cymbopogon citratus essential oil, commonly known as “lemongrass”, and has demonstrated potential antihyperalgesic, anti-nociceptive and anti-inflammatory effects. However, CIT shows high volatility, low solubility in water and consequent low bioavailability, which limits its use. Therefore, ...
- DOI:
- 10.1016/j.lfs.2019.05.026
- https://doi.org/10.1016/j.lfs.2019.05.026
- Author:
- Panpan Zhang; Yanlian Deng; Xiaojing Lin; Bin Chen; Jing Li; Hongju Liu; Senhua Chen; Lan Liu
- Source:
- Journal of natural products 2019 v.82 no.4 pp. 947-957
- ISSN:
- 1520-6025
- Subject:
- Trichoderma reesei; X-ray diffraction; anti-inflammatory activity; fungi; inhibitory concentration 50; lipopolysaccharides; moieties; nitric oxide; nuclear magnetic resonance spectroscopy; spectral analysis; structure-activity relationships
- Abstract:
- ... Eight new dimeric sorbicillinoids (1–3, 5–9) and 12 new monomeric sorbicillinoids (10–20, 25), along with five known analogues (4 and 21–24), were isolated from the marine-derived fungus Trichoderma reesei 4670. Their structures were elucidated on the basis of extensive spectroscopic analyses (1D and 2D NMR, HR-ESIMS, and ECD) and X-ray crystallography. Compound 1, containing a pyrrolidin-2-one mo ...
- DOI:
- 10.1021/acs.jnatprod.8b01029
- https://doi.org/10.1021/acs.jnatprod.8b01029
- Author:
- Kuang Xu; Xuan Zhang; Jing Wei Chen; Yan Shen; Nan Jiang; Ren Xiang Tan; Rui Hua Jiao; Hui Ming Ge
- Source:
- Tetrahedron letters 2019 pp. -
- ISSN:
- 0040-4039
- Subject:
- Diaporthe; X-ray diffraction; anti-inflammatory activity; biochemical pathways; chemical reactions; chemical structure; diterpenoids; endophytes; fungi; interleukin-1beta; interleukin-6; lipopolysaccharides; macrophages; nuclear magnetic resonance spectroscopy
- Abstract:
- ... Three new pimarane-type diterpenoids, along with two known compounds, were isolated from an endophytic fungus Phomopsis sp. S12. Their structures were determined by comprehensive analyses of HRESIMS, NMR, CD, as well as single-crystal X-ray diffractions. Compound 3 exhibited anti-inflammatory activity against the production of IL-1β and IL-6 induced by lipopolysaccharide (LPS) in macrophages. A pu ...
- DOI:
- 10.1016/j.tetlet.2019.151045
- https://doi.org/10.1016/j.tetlet.2019.151045
- Author:
- Panpan Zhang; Chunxiu Jia; Yanlian Deng; Senhua Chen; Bin Chen; Sujun Yan; Jing Li; Lan Liu
- Source:
- Phytochemistry 2019 v.158 pp. 120-125
- ISSN:
- 0031-9422
- Subject:
- Eurotium; X-ray diffraction; anti-inflammatory activity; cytotoxicity; fungi; inhibitory concentration 50; nuclear magnetic resonance spectroscopy; quinones; spectral analysis
- Abstract:
- ... Two undescribed prenylbenzaldehyde derivatives, cristaldehydes A and B, and an undescribed quinone derivative, cristaquinone A, along with seven known compounds were isolated from the fungus Eurotium cristatum. The structures of undescribed compounds were determined by spectroscopic analysis including NMR, HR-ESIMS, and single-crystal X-ray diffraction. This is the first report of identification o ...
- DOI:
- 10.1016/j.phytochem.2018.11.017
- https://doi.org/10.1016/j.phytochem.2018.11.017
7. Azaphilone Alkaloids with Anti-inflammatory Activity from Fungus Penicillium sclerotiorum cib-411
- Author:
- Jia-Lin Tang; Zong-Yuan Zhou; Tao Yang; Can Yao; Lin-Wei Wu; Guo-You Li
- Source:
- Journal of agricultural and food chemistry 2019 v.67 no.8 pp. 2175-2182
- ISSN:
- 1520-5118
- Subject:
- Penicillium; X-ray diffraction; alkaloids; anti-inflammatory activity; circular dichroism spectroscopy; cytotoxicity; fungi; inhibitory concentration 50; lipopolysaccharides; nitric oxide; nuclear magnetic resonance spectroscopy; rice; spectral analysis
- Abstract:
- ... Nine new azaphilone alkaloids, penazaphilones A–I (1–9), were isolated from the solid fermented rice culture of Penicillium sclerotiorum cib-411. The structures of compounds 1–9 were elucidated based on HRESIMS, NMR, and CD spectroscopic data. The structures of 5 and 8 were confirmed by X-ray crystallographic analyses. Biological evaluation showed that compounds 1, 5, 6, and 8 inhibited the produc ...
- DOI:
- 10.1021/acs.jafc.8b05628
- https://doi.org/10.1021/acs.jafc.8b05628
- Author:
- Qiangqiang Shi; Yanjie Huang; Haiguo Su; Ya Gao; Xingrong Peng; Lin Zhou; Xiaonian Li; Minghua Qiu
- Source:
- Phytochemistry 2019 v.168 pp. 112109
- ISSN:
- 0031-9422
- Subject:
- Ganoderma; X-radiation; X-ray diffraction; anti-inflammatory activity; chemical structure; fruiting bodies; inhibitory concentration 50; macrophage activation; nitric oxide; spectral analysis; steroids
- Abstract:
- ... Eight undescribed ergostane-type steroids, (22E,24R)-ergosta-7,22-dien-3β,5α-diol- 6,5-olide, (22E,24R)-ergosta-7,9(11),22-trien-3β,5β,6β-triol, (22E,24R)-6β-methoxy ergosta-7,9(11),22-trien-3β,5α,14β-triol, (22E,24R)-9α,15α-dihydroxyergosta-4,6,8 (14),22-tetraen-3-one, (22E,24R)-ergosta-5,8,22-trien-3β,11α-dihydroxyl-7-one, (22E,24R)-ergosta-4,7,22-trien-3β,9α,14β-trihydroxyl-6-one, (22E,24R)-erg ...
- DOI:
- 10.1016/j.phytochem.2019.112109
- https://doi.org/10.1016/j.phytochem.2019.112109
- Author:
- Ilma Nugrahani; Dwi Utami; Yuda Prasetya Nugraha; Hidehiro Uekusa; Rahel Hasianna; Aisyah Amalia Darusman
- Source:
- Heliyon 2019 v.5 no.12 pp. e02946
- ISSN:
- 2405-8440
- Subject:
- X-ray diffraction; anti-inflammatory activity; diclofenac; drugs; esterification; hydrogen; hydrophobic bonding; infrared spectroscopy; relative humidity; thermal analysis
- Abstract:
- ... This study aimed to collect the crystallographic data of ethyl diclofenac and discover a cocrystal from this ester with its parent, diclofenac acid, and to investigate their physicochemical properties and anti-inflammation activity. Firstly, ethyl diclofenac single crystal was isolated and continued by the cocrystal screening and isolation. Solid characterization was conducted by thermal analysis, ...
- DOI:
- 10.1016/j.heliyon.2019.e02946
- PubMed:
- 31890943
- PubMed Central:
- PMC6926240
- https://doi.org/10.1016/j.heliyon.2019.e02946
- Author:
- Guo-Lei Zhu; Luo-Sheng Wan; Xing-Rong Peng; Qiang-Qiang Shi; Xiao-Nian Li; Jian-Chao Chen; Lin Zhou; Ming-Hua Qiu
- Source:
- Journal of natural products 2019 v.82 no.9 pp. 2419-2429
- ISSN:
- 1520-6025
- Subject:
- Toona ciliata; X-ray diffraction; anti-inflammatory activity; chemical constituents of plants; crystallography; cytotoxicity; ethyl acetate; inhibitory concentration 50; limonoids; macrophages; moieties; neoplasm cells; nitric oxide; spectral analysis
- Abstract:
- ... Eight new limonoids, toononoids A–H (1–8), eight new B-seco-29-norlimonoids, toonanoronoids A–H (9–16), and seven known analogues were obtained from the EtOAc extract of the twigs and leaves of Toona ciliata. Compounds 2, 4, 8, and 16 are rare lactam-bearing limonoids. Compounds 1, 14, and 15 possess an unusual γ-methoxybutenolide moiety at C-17, while compounds 9, 10, and 15 have a rare 3β-hydrox ...
- DOI:
- 10.1021/acs.jnatprod.8b00954
- https://doi.org/10.1021/acs.jnatprod.8b00954
- Author:
- Mathilde Lorscheider; Nicolas Tsapis; Mujeeb ur-Rehman; Françoise Gaudin; Ivana Stolfa; Sonia Abreu; Simona Mura; Pierre Chaminade; Marion Espeli; Elias Fattal
- Source:
- Journal of controlled release 2019 v.296 pp. 179-189
- ISSN:
- 0168-3659
- Subject:
- X-ray diffraction; adverse effects; anti-inflammatory activity; blood serum; cartilage; crystallization; dexamethasone; encapsulation; glucocorticoids; inflammation; macrophages; mice; models; nanoparticles; palmitates; pharmacokinetics; phospholipids; polyethylene; remission; rheumatoid arthritis; storage temperature; therapeutics; water solubility; zeta potential
- Abstract:
- ... Rheumatoid arthritis (RA) is a prevalent autoimmune disease characterized by joint inflammation, bone and cartilage erosion. The use of glucocorticoids in the treatment of RA is hampered by significant side effects induced by their unfavorable pharmacokinetics. Delivering glucocorticoids by means of nanotechnologies is promising but the encapsulation of highly crystalline and poorly water-soluble ...
- DOI:
- 10.1016/j.jconrel.2019.01.015
- https://doi.org/10.1016/j.jconrel.2019.01.015
- Author:
- Ren-Qiang Mei; Feng-Jiao Zuo; Xiao-Yan Duan; Yi-Na Wang; Jun-Rong Li; Cheng-Zhen Qian; Ji-Ping Xiao
- Source:
- Phytochemistry letters 2019 v.32 pp. 177-180
- ISSN:
- 1874-3900
- Subject:
- Ganoderma; X-ray diffraction; anti-inflammatory activity; fruiting bodies; inhibitory concentration 50; nitric oxide; nuclear magnetic resonance spectroscopy
- Abstract:
- ... Three new ergosterols, ganocalidophins A–C (1‒3), along with four known ones, were isolated from the fruiting bodies of Ganoderma sinense. Their structures were established on the basis of extensive NMR and MS technologies, as well as the single crystal X-ray diffraction. Compounds 1‒3 and 6 exhibited inhibitory activities against NO production with IC50 of 17.7–32.4 μM. ...
- DOI:
- 10.1016/j.phytol.2019.06.006
- https://doi.org/10.1016/j.phytol.2019.06.006
- Author:
- Ghasem Rahimi Kalateh Shah Mohammad; Masoud Homayouni Tabrizi; Touran Ardalan; Soheyla Yadamani; Elham Safavi
- Source:
- Journal of biosciences 2019 v.44 no.2 pp. 30
- ISSN:
- 0250-5991
- Subject:
- Fourier transform infrared spectroscopy; X-ray diffraction; angiogenesis; anti-inflammatory activity; antineoplastic activity; blood vessels; breast neoplasms; carrageenan; cell lines; chorioallantoic membrane; cytotoxicity; edema; genes; inflammation; interleukin-10; mice; nanoparticles; neoplasm cells; scanning electron microscopy; transmission electron microscopy; vascular endothelial growth factors; zinc oxide
- Abstract:
- ... In this study, zinc oxide nanoparticles (ZnO-NPs) were synthesized using the extract of Hyssops officinalis L. via green method and confirmed by transmission electron microscopy, field emission scanning electron microscopy, X-ray powder diffraction and Fourier transforms infrared spectroscopy techniques. In the in vivo section, the anti-angiogenesis and anti-inflammatory properties of the NPs were ...
- DOI:
- 10.1007/s12038-019-9845-y
- https://doi.org/10.1007/s12038-019-9845-y
- Author:
- Wen-Jun Xu; Peng-Fei Tang; Wei-Jia Lu; Yan-Qiu Zhang; Xiao-Bing Wang; Hao Zhang; Jun Luo; Ling-Yi Kong
- Source:
- Organic letters 2019 v.21 no.21 pp. 8558-8562
- ISSN:
- 1523-7052
- Subject:
- Hypericum; X-ray diffraction; anti-inflammatory activity; biosynthesis; chemical reactions; chemical structure; circular dichroism spectroscopy; cytotoxicity; nuclear magnetic resonance spectroscopy; organic compounds
- Abstract:
- ... The first examples of type B polycyclic polyprenylated acylphloroglucinols with a bicyclo[5.3.1]hendecane core, hyperberins A (1) and B (2), were isolated from Hypericum beanii, together with three biosynthetic congeners. Their structures were established by a combination of NMR, electric circular dichroism (ECD), and X-ray diffraction analyses. These isolates indicated divergent cationic cyclizat ...
- DOI:
- 10.1021/acs.orglett.9b03098
- https://doi.org/10.1021/acs.orglett.9b03098
- Author:
- Geng Li; Heng Li; Wei Tang; Yue-Wei Guo; Xu-Wen Li
- Source:
- Organic letters 2019 v.21 no.14 pp. 5660-5664
- ISSN:
- 1523-7052
- Subject:
- X-ray diffraction; anti-inflammatory activity; biosynthesis; carbon; chemical reactions; chemical structure; corals; diterpenoids; quantum mechanics; spectral analysis; tumor necrosis factor-alpha
- Abstract:
- ... Two novel polyoxygenated diterpenoids, klyflaccilides A (1) and B (2), featuring an uncommon 6/5/8/3 tetracyclic ring system, were isolated from the Hainan soft coral Klyxum flaccidum. Their structures were established by extensive spectroscopic analysis, X-ray diffraction analysis, and/or a quantum chemical computation method. A plausible biosynthetic relationship of 1 and 2 with their potential ...
- DOI:
- 10.1021/acs.orglett.9b01998
- https://doi.org/10.1021/acs.orglett.9b01998
- Author:
- Yu-Dan Mei; Hai-Bo Li; Qian-Qian Pang; Ting Li; Da-Bo Pan; Yi Dai; Da-Peng Qin; He Meng; Xin-Sheng Yao; Yang Yu
- Source:
- RSC advances 2019 v.9 no.38 pp. 22011-22016
- ISSN:
- 2046-2069
- Subject:
- Lonicera; X-ray diffraction; aldehydes; anti-inflammatory activity; flower buds; inhibitory concentration 50; interleukin-6; iridoids; spectroscopy
- Abstract:
- ... Lonimacranaldes A and B (1 and 2), along with one biogenetically related intermediate, lonimacranalde C (3), were isolated from the flower buds of Lonicera macranthoides. Characterized by an iridoid structure and an additional C-6 unit with an aldehyde group, compounds 1 and 2 are the first examples of hybrid iridoids possessing an unexpected 6/5/6 fused tricyclic ring system, while compound 3 ser ...
- DOI:
- 10.1039/c9ra04029c
- https://doi.org/10.1039/c9ra04029c
17. Macrocyclic Diterpenoids from Euphorbia helioscopia and Their Potential Anti-inflammatory Activity
- Author:
- Jun-Cheng Su; Wen Cheng; Jian-Guo Song; Yuan-Lin Zhong; Xiao-Jun Huang; Ren-Wang Jiang; Yao-Lan Li; Man-Mei Li; Wen-Cai Ye; Ying Wang
- Source:
- Journal of natural products 2019 v.82 no.10 pp. 2818-2827
- ISSN:
- 1520-6025
- Subject:
- Euphorbia helioscopia; X-ray diffraction; aerial parts; anti-inflammatory activity; diterpenoids; inhibitory concentration 50; interleukin-6; monitoring; nitric oxide; nuclear magnetic resonance spectroscopy; protons; secretion; signal transduction; spectral analysis; transcription factor NF-kappa B; tumor necrosis factor-alpha
- Abstract:
- ... Guided by ¹H NMR spectroscopic experiments using the aromatic protons as probes, 11 macrocyclic diterpenes (1–11) were isolated from the aerial parts of Euphorbia helioscopia. Their full three-dimensional structures, including absolute configurations, were established unambiguously by spectroscopic analysis and single-crystal X-ray crystallographic experiments. Among the isolated compounds, compou ...
- DOI:
- 10.1021/acs.jnatprod.9b00519
- https://doi.org/10.1021/acs.jnatprod.9b00519
- Author:
- Ying-Ying Huang; Xin Qiu; Yang-Guo Xie; Guo-Jing Wu; Sheng-Lan Zhu; Wei-Dong Zhang; Yan Zhang; Chen Dai-Jie; Hui-Zi Jin
- Source:
- Phytochemistry letters 2019 v.31 pp. 125-130
- ISSN:
- 1874-3900
- Subject:
- X-ray diffraction; anti-inflammatory activity; circular dichroism spectroscopy; copper; inhibitory concentration 50; lignans; macrophages; nitric oxide; nuclear magnetic resonance spectroscopy; terpenoids
- Abstract:
- ... Two new acetylenic compounds (1 and 2), two new lignans (3 and 4) along with eight known lignans (5−12), ten known terpenoids (13−22) and one known aromatic compound (23) were isolated from the whole plants of Dolomiaea berardioidea (Franch.) Shih. Structures of new compounds were elucidated by combined use of HRESIMS, 1D and 2D NMR and CD spectroscopic methods. The absolute structures of 1 and 3 ...
- DOI:
- 10.1016/j.phytol.2019.03.012
- https://doi.org/10.1016/j.phytol.2019.03.012
- Author:
- Yang-Guo Xie; Xin-Cai Zhao; Syed Shams ul Hassan; Xiao-Yong Zhen; Ishaq Muhammad; Shi-kai Yan; Xing Yuan; Hui-liang Li; Hui-zi Jin
- Source:
- Phytochemistry letters 2019 v.32 pp. 6-9
- ISSN:
- 1874-3900
- Subject:
- Valeriana; X-ray diffraction; anti-inflammatory activity; inhibitory concentration 50; irradiation; macrophages; nitric oxide; sesquiterpenoids; spectral analysis; stereochemistry
- Abstract:
- ... One new sesquiterpene 1S, 3S, 4S, 7S 3,4-dihydroxy-bisabolol (1), one new iridoid amurensin A (2) and 10 known compounds were isolated from the whole plants of Valeriana amurensis. Their structures were established on the basis of extensive spectroscopic analysis and the absolute stereochemistry of compound 1 was assigned by X-ray diffraction analysis with Cu-Kα irradiation. All of compounds were ...
- DOI:
- 10.1016/j.phytol.2019.04.020
- https://doi.org/10.1016/j.phytol.2019.04.020
- Author:
- Rehebati Nuerxiati; Aytursun Abuduwaili; Paiheerding Mutailifu; Atikan Wubulikasimu; Nigora Rustamova; Cui Jingxue; Haji Akber Aisa; Abulimiti Yili
- Source:
- International journal of biological macromolecules 2019 v.141 pp. 431-443
- ISSN:
- 0141-8130
- Subject:
- Fourier transform infrared spectroscopy; Orchis; X-ray diffraction; anti-inflammatory activity; antioxidant activity; chemical composition; cytotoxicity; experimental design; food industry; free radicals; gas chromatography-mass spectrometry; glucose; mannose; molecular weight; nuclear magnetic resonance spectroscopy; polysaccharides; raw materials; response surface methodology; scanning electron microscopy; temperature; thermogravimetry; toxicity testing; ultrasonics
- Abstract:
- ... In the present study, ultrasonic-assisted extraction (UAE) of polysaccharides from Orchis chusua D. Don (salep) was optimized by response surface methodology (RSM) combined with a Box–Behnken design (BBD), the optimum conditions were determined to be: ultrasonic power of 390 W, extraction temperature of 60 °C, extraction time of 50 min and water/raw material ratio of 40 mL/g. Based on it, 48.30 ± ...
- DOI:
- 10.1016/j.ijbiomac.2019.08.112
- https://doi.org/10.1016/j.ijbiomac.2019.08.112