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You searched for: Publication year rev 7981-2019 Remove constraint Publication year rev: 7981-2019 Subject term antibiotic resistance Remove constraint Subject term: antibiotic resistance
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1. The 1-β-methyl group confers a lower affinity of l,d-transpeptidase LdtMt2 for ertapenem than for imipenem

Author:
Fen Zhao; Yan-Jie Hou; Ying Zhang; Da-Cheng Wang; De-Feng Li
Source:
Biochemical and biophysical research communications 2019 v.510 no.2 pp. 254-260
ISSN:
0006-291X
Subject:
antibiotic resistance; bacteria; drug design; enzymes; ertapenem; imipenem; moieties; pathogens; tuberculosis; virulence
Abstract:
... L,D-transpeptidases, widely distributed in bacteria and even in the difficult-to-treat ESKAPE pathogens, can confer antibacterial resistance against the traditional β-lactam antibiotics through bypass of the 4 → 3 transpeptide linkage. LdtMt2, a l,d-transpeptidase in Mycobacteria tuberculosis, is essential for bacterial virulence and is considered as a potential anti-tuberculosis target inhibited ...
DOI:
10.1016/j.bbrc.2019.01.082

2. Elizabethkingia Infections in Humans: From Genomics to Clinics

Author:
Jiun-Nong Lin; Chung-Hsu Lai; Chih-Hui Yang; Yi-Han Huang
Source:
Microorganisms 2019 v.7 no.9 pp. -
ISSN:
2076-2607
Subject:
aminoglycosides; antibiotic resistance; carbapenems; databases; desorption; essential genes; fluoroquinolones; genomics; humans; mass spectrometry; microorganisms; minocycline; mutation; new species; pathogens; patients; piperacillin; sequence analysis; species identification
Abstract:
... The genus Elizabethkingia has recently emerged as a cause of life-threatening infections in humans, particularly in immunocompromised patients. Several new species in the genus Elizabethkingia have been proposed in the last decade. Numerous studies have indicated that Elizabethkingia anophelis, rather than Elizabethkingia meningoseptica, is the most prevalent pathogen in this genus. Matrix-assiste ...
DOI:
10.3390/microorganisms7090295
PubMed:
31466280
PubMed Central:
PMC6780780

3. Moraxella nonliquefaciens and M. osloensis Are Important Moraxella Species That Cause Ocular Infections

Author:
Samantha J. LaCroce; Mollie N. Wilson; John E. Romanowski; Jeffrey D. Newman; Vishal Jhanji; Robert M. Q. Shanks; Regis P. Kowalski
Source:
Microorganisms 2019 v.7 no.6 pp. -
ISSN:
2076-2607
Subject:
Acinetobacter lwoffii; Moraxella bovis; Moraxella catarrhalis; Moraxella lacunata; Moraxella nonliquefaciens; Moraxella osloensis; Roseomonas; antibiotic resistance; bacteria; conjunctivitis; eyes; keratitis; matrix-assisted laser desorption-ionization mass spectrometry; pathogens; sequence analysis; vancomycin
Abstract:
... Moraxella is an ocular bacterial pathogen isolated in cases of keratitis, conjunctivitis, and endophthalmitis. Gram-negative brick-shaped diplobacilli from ocular specimens, and slow growth in culture, are early indications of Moraxella ocular infection; however, identifying Moraxella to species can be complex and inconsistent. In this study, bacteria consistent with Moraxella were identified to s ...
DOI:
10.3390/microorganisms7060163
PubMed:
31167433
PubMed Central:
PMC6616425

4. Olea europaea L. Root Endophyte Bacillus velezensis OEE1 Counteracts Oomycete and Fungal Harmful Pathogens and Harbours a Large Repertoire of Secreted and Volatile Metabolites and Beneficial Functional Genes

Author:
Manel Cheffi; Ali Chenari Bouket; Faizah N. Alenezi; Lenka Luptakova; Marta Belka; Armelle Vallat; Mostafa E. Rateb; Slim Tounsi; Mohamed Ali Triki; Lassaad Belbahri
Source:
Microorganisms 2019 v.7 no.9 pp. -
ISSN:
2076-2607
Subject:
Bacillus velezensis; Fusarium solani; Olea europaea; Phytophthora cryptogea; Phytophthora ramorum; antibiotic resistance; antibiotics; aromatic compounds; biofertilizers; biological control; biological control agents; chemical treatment; disease outbreaks; endophytes; financial economics; forest ecosystems; fungi; gas chromatography-mass spectrometry; genes; genome mining; greenhouse experimentation; growth promotion; human health; liquid chromatography; metals; microbiome; olives; pathogens; phytotoxicity; plant growth; plant growth-promoting rhizobacteria; roots; screening; secondary metabolites; sequence analysis; volatile organic compounds
Abstract:
... Oomycete and fungal pathogens, mainly Phytophthora and Fusarium species, are notorious causal agents of huge economic losses and environmental damages. For instance, Phytophthora ramorum, Phytophthora cryptogea, Phytophthora plurivora and Fusarium solani cause significant losses in nurseries and in forest ecosystems. Chemical treatments, while harmful to the environment and human health, have been ...
DOI:
10.3390/microorganisms7090314
PubMed:
31484434
PubMed Central:
PMC6780883

5. Staphylococcus xylosus Infection in Rainbow Trout (Oncorhynchus mykiss) As a Primary Pathogenic Cause of Eye Protrusion and Mortality

Author:
Woo Taek Oh; Jin Woo Jun; Sib Sankar Giri; Saekil Yun; Hyoun Joong Kim; Sang Guen Kim; Sang Wha Kim; Se Jin Han; Jun Kwon; Se Chang Park
Source:
Microorganisms 2019 v.7 no.9 pp. -
ISSN:
2076-2607
Subject:
Oncorhynchus mykiss; Staphylococcus xylosus; antibiotic resistance; bacteria; eyes; financial economics; fish diseases; fisheries; hospitals; humans; livestock; methicillin; methicillin-resistant Staphylococcus aureus; mortality; pathogenicity; public health; risk; signs and symptoms (animals and humans); staphylococcal infections; trout; wild animals; zoonoses
Abstract:
... Staphylococcal infections are extensively investigated in humans owing to the resistance of staphylococci to diverse antibiotics commonly used in hospitals. The resistance mechanism of methicillin-resistant Staphylococcus aureus has garnered the interest of researchers due to its risk to the global public health. Furthermore, the zoonotic potential of staphylococci has led to increased interest in ...
DOI:
10.3390/microorganisms7090330
PubMed:
31500280
PubMed Central:
PMC6780347

6. ABC-F proteins in mRNA translation and antibiotic resistance

Author:
Farès Ousalem; Shikha Singh; Olivier Chesneau; John F. Hunt; Grégory Boël
Source:
Research in microbiology 2019 v.170 no.8 pp. 435-447
ISSN:
0923-2508
Subject:
adenosine triphosphate; adenosinetriphosphatase; antibiotic resistance; antibiotics; geometry; mechanism of action; messenger RNA; microbial proteins; ribosomes; stereochemistry; transfer RNA; transferases; translation (genetics)
Abstract:
... The ATP binding cassette protein superfamily comprises ATPase enzymes which are, for the most part, involved in transmembrane transport. Within this superfamily however, some protein families have other functions unrelated to transport. One example is the ABC-F family, which comprises an extremely diverse set of cytoplasmic proteins. All of the proteins in the ABC-F family characterized to date ac ...
DOI:
10.1016/j.resmic.2019.09.005

7. ABCF ATPases Involved in Protein Synthesis, Ribosome Assembly and Antibiotic Resistance: Structural and Functional Diversification across the Tree of Life

Author:
Victoriia Murina; Marje Kasari; Hiraku Takada; Mariliis Hinnu; Chayan Kumar Saha; James W. Grimshaw; Takahiro Seki; Michael Reith; Marta Putrinš; Tanel Tenson; Henrik Strahl; Vasili Hauryliuk; Gemma Catherine Atkinson
Source:
Journal of molecular biology 2019 v.431 no.18 pp. 3568-3590
ISSN:
0022-2836
Subject:
Bacillus subtilis; Escherichia coli; Saccharomyces cerevisiae; adenosinetriphosphatase; ancestry; animal pathogens; antibiotic resistance; antibiotics; evolution; genome; guanosinetriphosphatase; mutants; protein synthesis; ribosomes; transferases
Abstract:
... Within the larger ABC superfamily of ATPases, ABCF family members eEF3 in Saccharomyces cerevisiae and EttA in Escherichia coli have been found to function as ribosomal translation factors. Several other ABCFs including biochemically characterized VgaA, LsaA and MsrE confer resistance to antibiotics that target the peptidyl transferase center and exit tunnel of the ribosome. However, the diversity ...
DOI:
10.1016/j.jmb.2018.12.013
PubMed:
30597160
PubMed Central:
PMC6723617

8. ATP-Dependent Dynamic Protein Aggregation Regulates Bacterial Dormancy Depth Critical for Antibiotic Tolerance

Author:
Yingying Pu; Yingxing Li; Xin Jin; Tian Tian; Qi Ma; Ziyi Zhao; Ssu-yuan Lin; Zhanghua Chen; Binghui Li; Guang Yao; Mark C. Leake; Chien-Jung Lo; Fan Bai
Source:
Molecular cell 2019 v.73 no.1 pp. 143-156.e4
ISSN:
1097-2765
Subject:
adenosine triphosphate; antibiotic resistance; antibiotics; bacteria; dormancy; regrowth; therapeutics
Abstract:
... Cell dormancy is a widespread mechanism used by bacteria to evade environmental threats, including antibiotics. Here we monitored bacterial antibiotic tolerance and regrowth at the single-cell level and found that each individual survival cell shows different “dormancy depth,” which in return regulates the lag time for cell resuscitation after removal of antibiotic. We further established that pro ...
DOI:
10.1016/j.molcel.2018.10.022

9. Ability of Vibrio vulnificus isolated from fish of the Lagoa dos Patos estuary in south Brazil to form biofilms after sublethal stress and bacterial resistance to antibiotics and sanitizers

Author:
Débora Rodrigues Silveira; Janaina Viana da Rosa; Kauana Kaefer; Luiz Gustavo Bach; Amanda de Oliveira Barbosa; Cláudio Dias Timm
Source:
International journal of food microbiology 2019 v.303 pp. 19-25
ISSN:
0168-1605
Subject:
Lagoa; Micropogonias furnieri; Paralichthys orbignyanus; Vibrio vulnificus; anti-infective agents; antibiotic resistance; biofilm; chlorine dioxide; estuaries; fish; fish industry; sanitizers; sodium hypochlorite; Brazil
Abstract:
... The present study aimed to investigate the presence of Vibrio vulnificus in fish captured at the Lagoa dos Patos estuary (RS, Brazil), to establish a correlation between bacterial biofilm formation and sublethal stress, and to assess the resistance of the isolates to antimicrobials and sanitizers. A total of 217 isolates characteristic of Vibrio sp. were analyzed. Isolates were identified and subs ...
DOI:
10.1016/j.ijfoodmicro.2019.05.007

10. Abundance and Antimicrobial Resistance of Three Bacterial Species along a Complete Wastewater Pathway

Author:
Ilse Verburg; Silvia García-Cobos; Lucia Hernández Leal; Karola Waar; Alex W. Friedrich; Heike Schmitt
Source:
Microorganisms 2019 v.7 no.9 pp. -
ISSN:
2076-2607
Subject:
Aeromonas; Escherichia coli; Klebsiella; anti-infective agents; antibiotic residues; antibiotic resistance; bacteria; feces; hospitals; surface water; wastewater; wastewater treatment; water pollution
Abstract:
... After consumption, antibiotic residues and exposed bacteria end up via the feces in wastewater, and therefore wastewater is believed to play an important role in the spread of antimicrobial resistance (AMR). We investigated the abundance and AMR profiles of three different species over a complete wastewater pathway during a one-year sampling campaign, as well as including antimicrobial consumption ...
DOI:
10.3390/microorganisms7090312
PubMed:
31484380
PubMed Central:
PMC6780886

11. Abundances of Tetracycline Resistance Genes and Tetracycline Antibiotics during Anaerobic Digestion of Swine Waste

Author:
Melanie Couch; Getahun E. Agga; John Kasumba; Rohan R. Parekh; John H. Loughrin; Eric D. Conte
Source:
Journal of environmental quality 2019 v.48 no.1 pp. 171-178
ISSN:
0047-2425
Subject:
anaerobic digestion; antibiotic resistance; antibiotic resistance genes; bacteria; biogas; chlortetracycline; corn; crop production; gas production (biological); liquids; pig manure; ribosomal RNA; sludge; swine; tetracycline
Abstract:
... The impact of anaerobic digestion of animal waste on the persistence of antibiotic resistance genes (ARGs) and antibiotics is not widely studied. Two identical, 800‐L digesters seeded with swine slurry were followed up to 100 d in three separate trials. The trials received varying amounts of antibiotic‐free corn (Zea mays L.) mixed with water to maintain the digestion process. Biogas production, s ...
Handle:
10113/6471053
DOI:
10.2134/jeq2018.09.0331

12. Acetic Acid Increased the Inactivation of Multi-drug Resistant Non-typhoidal Salmonella by Large-Scaffold Antibiotic

Author:
Vinicius Silva Castro; Bruno Serpa Vieira; Adelino Cunha-Neto; Eduardo Eustáquio de Souza Figueiredo; Carlos Adam Conte-Junior
Source:
Indian journal of microbiology 2019 v.59 no.4 pp. 508-513
ISSN:
0046-8991
Subject:
Gram-negative bacteria; Salmonella; acetic acid; agar; analysis of variance; antibiotic resistance; brain; cell walls; heart; mechanism of action; multiple drug resistance; permeability; screening; vancomycin
Abstract:
... Salmonella is a gram-negative bacterium with intrinsic resistance to large-scaffold antibiotics due to the presence of an outer membrane. Based on the mode of action of the organic acids in outer membrane disintegration, and consequently, an enhancement in cell permeability, a combination of acetic acid and a large-scaffold antibiotic is it evaluated. Therefore, the aim of this study is to assess ...
DOI:
10.1007/s12088-019-00837-7
PubMed:
31762515
PubMed Central:
PMC6842369

13. Acinetobacter baumannii analysis by core genome multi-locus sequence typing in two hospitals in Bolivia: endemicity of international clone 7 isolates (CC25)

Author:
Mónica Cerezales; Kyriaki Xanthopoulou; Julia Wille; Zulema Bustamante; Harald Seifert; Lucía Gallego; Paul G. Higgins
Source:
International journal of antimicrobial agents 2019 v.53 no.6 pp. 844-849
ISSN:
0924-8579
Subject:
Acinetobacter baumannii; agar; alleles; antibiotic resistance; antibiotic resistance genes; beta-lactamase; carbapenems; clones; crabs; genome assembly; hospitals; indigenous species; minimum inhibitory concentration; molecular epidemiology; patients; polymerase chain reaction; transposons; Bolivia
Abstract:
... In total, 95 Acinetobacter baumannii isolates recovered from patients from two hospitals in Cochabamba, Bolivia were studied. The presence of class D and B β-lactamases was investigated using polymerase chain reaction, and antimicrobial susceptibility testing was performed by agar dilution and broth microdilution. The resistance rate to carbapenems was 53.7%. All carbapenem-resistant A. baumannii ...
DOI:
10.1016/j.ijantimicag.2019.03.019

14. Acinetobacter baumannii – a neglected pathogen in veterinary and environmental health in Germany

Author:
Gamal Wareth; Heinrich Neubauer; Lisa D. Sprague
Source:
Veterinary research communications 2019 v.43 no.1 pp. 1-6
ISSN:
0165-7380
Subject:
Acinetobacter baumannii; antibiotic resistance; bacterial infections; case studies; environmental health; farmed animal species; monitoring; pathogens; pets; wildlife; Germany
Abstract:
... The emergence and global spread of drug resistant Acinetobacter (A.) baumannii is a cause of great concern. The current knowledge on antibiotic resistance in A. baumannii from animal origin is mostly based on few internationally published case reports, investigations of strain collections and several whole genome analyses. This lack of data results in a somewhat sketchy picture on how to assess th ...
DOI:
10.1007/s11259-018-9742-0

15. Acinetobacter species in laboratory mice: species survey and antimicrobial resistance

Author:
Laurentiu Benga; Andrea T. Feßler; W. Peter M. Benten; Eva Engelhardt; Karl Köhrer; Stefan Schwarz; Martin Sager
Source:
Laboratory animals 2019 v.53 no.5 pp. 470-477
ISSN:
1758-1117
Subject:
Acinetobacter radioresistens; antibiotic resistance; cephalothin; epidemiology; florfenicol; laboratory animals; mice; minimum inhibitory concentration; monitoring; multiple drug resistance; ribosomal RNA; sequence analysis; streptomycin; surveys; therapeutics; tiamulin
Abstract:
... The extra-hospital epidemiology of Acinetobacter infections is a subject of debate. In recent years, the prevalence of animal multidrug-resistant Acinetobacter infections has increased considerably. The goal of the present study was to specify Acinetobacter species isolated from laboratory mice and to test them for their antimicrobial susceptibility. During routine microbiological monitoring of la ...
DOI:
10.1177/0023677218818598

16. Acute Endometritis due to Taylorella equigenitalis Transmission by Insemination of Cryopreserved Stallion Semen

Author:
Marie Delerue; Marie-France Breuil; Fabien Duquesne; Marie-Hélène Bayon-Auboyer; Nadia Amenna-Bernard; Sandrine Petry
Source:
Journal of equine veterinary science 2019 v.78 pp. 10-13
ISSN:
0737-0806
Subject:
Taylorella equigenitalis; antibiotic resistance; artificial insemination; contagious equine metritis; cryopreservation; endometritis; insemination; mares; multilocus sequence typing; screening; semen; stallions
Abstract:
... Taylorella equigenitalis can be transmitted during artificial insemination. This report describes clinical T. equigenitalis transmission by cryopreserved stallion semen. T. equigenitalis isolates from a mare's vaginal discharge and semen from the same batch of the cryopreserved semen used for the insemination gave identical API ZYM, antibiotic susceptibility, and multilocus sequence typing results ...
DOI:
10.1016/j.jevs.2019.03.217

17. Adaptation and diversification in virulence factors among urinary catheter‐associated Pseudomonas aeruginosa isolates

Author:
C. Vipin; M. Mujeeburahiman; A.B. Arun; P. Ashwini; S.V. Mangesh; P.D. Rekha
Source:
Journal of applied microbiology 2019 v.126 no.2 pp. 641-650
ISSN:
1364-5072
Subject:
Pseudomonas aeruginosa; antibiotic resistance; antibiotics; biofilm; blood serum; confocal laser scanning microscopy; drugs; gentian violet; host-pathogen relationships; humans; kidney cells; multiple drug resistance; pathogens; patients; polystyrenes; protocols; ribosomal RNA; scanning electron microscopy; sequence analysis; staining; urinary tract diseases; virulence
Abstract:
... AIM: The aim of this study was to investigate the natural variation in the antibiotic sensitivity, biofilm formation and virulence among Pseudomonas aeruginosa isolated from the catheter‐associated urinary tract infection (CAUTI) from a single centre. METHODS AND RESULTS: Pseudomonas aeruginosa strains were isolated from the patients with CAUTI after obtaining informed consent. These isolates were ...
DOI:
10.1111/jam.14143

18. Adaptation of Pseudomonas aeruginosa clinical isolates to benzalkonium chloride retards its growth and enhances biofilm production

Author:
Tarek El-Banna; Ahmed Abd El-Aziz; Fatma Sonbol; Engy El-Ekhnawy
Source:
Molecular biology reports 2019 v.46 no.3 pp. 3437-3443
ISSN:
0301-4851
Subject:
Pseudomonas aeruginosa; antibiotic resistance; antibiotics; benzalkonium chloride; biocides; biofilm; disinfectants; gene overexpression; genes; gentian violet; growth retardation; hospitals; hydrophobicity; reverse transcriptase polymerase chain reaction; secondary infection; transcription (genetics)
Abstract:
... The increasing percentage of Pseudomonas aeruginosa strains that are resistant to multiple antibiotics is a global problem. The exposure of P. aeruginosa isolates to repeated sub lethal concentrations of biocides in hospitals and communities may be one of the causes leading to increased antibiotic resistance. Benzalkonium chloride (BAC) is widely used as disinfectant and preservative. This study i ...
DOI:
10.1007/s11033-019-04806-7

19. Adaptive Evolution of Escherichia coli to Ciprofloxacin in Controlled Stress Environments: Contrasting Patterns of Resistance in Spatially Varying versus Uniformly Mixed Concentration Conditions

Author:
Jinzi Deng; Lang Zhou; Robert A. Sanford; Lauren A. Shechtman; Yiran Dong; Reinaldo E. Alcalde; Mayandi Sivaguru; Glenn A. Fried; Charles J. Werth; Bruce W. Fouke
Source:
Environmental science & technology 2019 v.53 no.14 pp. 7996-8005
ISSN:
1520-5851
Subject:
Escherichia coli; antibiotic resistance; antibiotics; biomass; ciprofloxacin; environmental science; evolutionary adaptation; minimum inhibitory concentration; technology
Abstract:
... A microfluidic gradient chamber (MGC) and a homogeneous batch culturing system were used to evaluate whether spatial concentration gradients of the antibiotic ciprofloxacin allow development of greater antibiotic resistance in Escherichia coli strain 307 (E. coli 307) compared to exclusively temporal concentration gradients, as indicated in an earlier study. A linear spatial gradient of ciprofloxa ...
DOI:
10.1021/acs.est.9b00881

20. Addiction systems antagonize bacterial adaptive immunity

Author:
Lisa van Sluijs; Stineke van Houte; John van der Oost; Stan JJ Brouns; Angus Buckling; Edze R Westra
Source:
FEMS microbiology letters 2019 v.366 no.5 pp. -
ISSN:
1574-6968
Subject:
CRISPR-Cas systems; Escherichia coli; adaptive immunity; antibiotic resistance; antibiotics; genes; interspersed repetitive sequences; plasmids; toxicity; toxins
Abstract:
... CRISPR-Cas systems provide adaptive immunity against mobile genetic elements, but employment of this resistance mechanism is often reported with a fitness cost for the host. Whether or not CRISPR-Cas systems are important barriers for the horizontal spread of conjugative plasmids, which play a crucial role in the spread of antibiotic resistance, will depend on the fitness costs of employing CRISPR ...
DOI:
10.1093/femsle/fnz047
PubMed:
30834930
PubMed Central:
PMC6478593