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7981-2019
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antineoplastic activity
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Oriental traditional medicine
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cytotoxicity
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- Author:
- Tingting Fang; Yuan Fang; Xiaojing Xu; Mingyan He; Zhiying Zhao; Peixin Huang; Feifei Yuan; Mengzhou Guo; Biwei Yang; Jinglin Xia
- Source:
- Journal of ethnopharmacology 2019 v.231 pp. 474-485
- ISSN:
- 0378-8741
- Subject:
- Actinidia chinensis; Oriental traditional medicine; animal models; antineoplastic activity; apoptosis; cell proliferation; cell viability; cytotoxicity; diuresis; gene expression; gene expression regulation; genes; hemostasis; hepatoma; herbs; messenger RNA; metastasis; patients; prognosis; quantitative polymerase chain reaction
- Abstract:
- ... Numerous studies have demonstrated the potent anticancer activity of various Chinese herbs. Actinidia chinensis Planch root (acRoots), a traditional Chinese medicine, functions as an antitumor and detoxifying agent and plays a role in diuresis and hemostasis. Treatment with acRoots confers strong inhibition of tumor growth in various forms of cancer. Here, we evaluated the anticancer activity and ...
- DOI:
- 10.1016/j.jep.2018.11.014
- https://doi.org/10.1016/j.jep.2018.11.014
- Author:
- Mohamad Hesam Shahrajabian; Wenli Sun; Qi Cheng
- Source:
- Acta agriculturæ Scandinavica 2019 v.69 no.6 pp. 546-556
- ISSN:
- 1651-1913
- Subject:
- Oriental traditional medicine; Zingiber officinale; analgesic effect; anti-inflammatory activity; antineoplastic activity; antioxidants; ascorbic acid; baked goods; calcium; cold; constipation; cytotoxicity; dementia; fever; flavonoids; food industry; ginger; herbal medicines; hypertension; indigestion; infectious diseases; iron; leaves; magnesium; medicinal plants; nutritive value; oils; pain; pharmaceutical industry; phenolic compounds; pickles; preservatives; rheumatoid arthritis; sauces; sesquiterpenoids; soft drinks; sweets; vomiting; China
- Abstract:
- ... Ginger (Zingiber officinale) has been used as a spice and medicine for over 200 years in Traditional Chinese Medicine. It is an important plant with several medicinal, and nutritional values used in Asian and Chinese Tradition medicine. Ginger and its general compounds such as Fe, Mg, Ca, vitamin C, flavonoids, phenolic compounds (gingerdiol, gingerol, gingerdione and shogaols), sesquiterpenes, pa ...
- DOI:
- 10.1080/09064710.2019.1606930
- https://doi.org/10.1080/09064710.2019.1606930
- Author:
- Lan Ma; Xue Zhang; Xiaoming Xu; Yuehai Ke; Jin Dai; Hongqiang Cheng; Wei Mao
- Source:
- Journal of ethnopharmacology 2019 v.231 pp. 507-515
- ISSN:
- 0378-8741
- Subject:
- Oriental traditional medicine; antineoplastic activity; cardiovascular diseases; cytotoxicity; herbs; polymerization; tubulin
- Abstract:
- ... The concept of the prescription in Traditional Chinese Medicine (TCM) is usually characterized by the compatibility principle “monarch, minister, assistant, and guide”, which means herbs play primary, secondary, auxiliary, or harmonic roles, respectively, to achieve the optimally holistic effect. Following this compatibility principle, the Tanyu Tongzhi Formula (TTF), used for many years to treat ...
- DOI:
- 10.1016/j.jep.2018.11.043
- https://doi.org/10.1016/j.jep.2018.11.043
- Author:
- Chong Li; Guangbin Huang; Fang Tan; Xianrong Zhou; Jianfei Mu; Xin Zhao
- Source:
- Journal of food quality 2019 v.2019 pp. -
- ISSN:
- 0146-9428
- Subject:
- 2,2-diphenyl-1-picrylhydrazyl; Apocynum venetum; Oriental traditional medicine; antineoplastic activity; antioxidant activity; antioxidant genes; apoptosis; bioactive compounds; caspase-3; caspase-9; catalase; cell proliferation; cell viability; chlorogenic acid; cytotoxicity; dose response; free radical scavengers; free radicals; gene expression; gene expression regulation; glutathione peroxidase; hepatoma; high performance liquid chromatography; human cell lines; human diseases; hydrogen peroxide; in vitro studies; kidneys; leaves; messenger RNA; polyphenols; protective effect; quantitative polymerase chain reaction; quercetin; reverse transcriptase polymerase chain reaction; rosmarinic acid; rutin; spectroscopy; sulfonic acids; superoxide dismutase; survival rate; tea; toxicity testing
- Abstract:
- ... The dry leaf of Apocynum venetum tea extracts (AVTEs) belonging to the Apocynaceae family is a traditional Chinese medicine. The aim of this study is to identify the bioactive components of AVTE and analyse its antioxidant and anticancer activity in vitro. Method. Flavones and polyphenols in AVTE were determined by high-performance liquid chromatography (HPLC) assay. The scavenging capacity of tea ...
- DOI:
- 10.1155/2019/2465341
- https://doi.org/10.1155/2019/2465341
- Author:
- Zheng LI; Qian-Qian CHEN; Christopher Wai Kei LAM; Jian-Ru GUO; Wei-Jia ZHANG; Cai-Yun WANG; Vincent Kam Wai WONG; Mei-Cun YAO; Wei ZHANG
- Source:
- Chinese journal of natural medicines 2019 v.17 no.8 pp. 608-615
- ISSN:
- 1875-5364
- Subject:
- DNA replication; Oriental traditional medicine; adenocarcinoma; antineoplastic activity; cell cycle checkpoints; cell lines; cytotoxicity; epithelial cells; humans; hydroxyurea; interphase; liquid chromatography; lungs; mass spectrometry; metabolism; metabolomics; nucleosides; resveratrol
- Abstract:
- ... In an effort to understand the molecular events contributing to the cytotoxicity activity of resveratrol (RSV), we investigated its effects on human lung adenocarcinoma epithelial cell line A549 at different concentrations. Cellular nucleoside metabolic profiling was determined by an established liquid chromatography-mass spectrometry method in A549 cells. RSV resulted in significant decreases and ...
- DOI:
- 10.1016/S1875-5364(19)30063-9
- https://doi.org/10.1016/S1875-5364(19)30063-9
- Author:
- Qing Lin; Mengke Qu; Hirak K. Patra; Shanshan He; Luyao Wang; Xun Hu; Linyu Xiao; Yu Fu; Tao Gong; Qin He; Ling Zhang; Xun Sun; Zhirong Zhang
- Source:
- Journal of ethnopharmacology 2019 pp. -
- ISSN:
- 0378-8741
- Subject:
- Fritillaria cirrhosa; Oriental traditional medicine; Western blotting; active ingredients; adverse effects; animal models; antineoplastic activity; antineoplastic agents; blood cell counts; cancer therapy; case studies; cell lines; cytotoxicity; drug delivery systems; enzyme-linked immunosorbent assay; films (materials); herbal medicines; histopathology; immunohistochemistry; in vivo studies; inflammation; lung neoplasms; mice; transcription factor NF-kappa B
- Abstract:
- ... Bulbus Fritillaria cirrhosa D. Don (BFC) is a Chinese traditional herbal medicine that has long been used as an indispensable component in herbal prescriptions for bronchopulmonary diseases due to its well-established strong anti-inflammation and pulmonary harmonizing effects. Interestingly, there are few case reports in traditional Chinese medicine available where they found it to contribute in a ...
- DOI:
- 10.1016/j.jep.2019.112283
- https://doi.org/10.1016/j.jep.2019.112283
- Author:
- Yalan Zhang; Yuhang Xiao; Qixing Dong; Wenjuan Ouyang; Qun Qin
- Source:
- Journal of food science 2019 v.84 no.4 pp. 904-910
- ISSN:
- 0022-1147
- Subject:
- Lotus; Oriental traditional medicine; alkaloids; antineoplastic activity; anxiety; cytotoxicity; dose response; enzyme inhibitors; heat-shock protein 90; herbal medicines; inhibitory concentration 50; messenger RNA; myeloid leukemia; neoplasm cells; patients; plumule; protein content; protein kinases; prototypes; relapse; sleep disorders; synergism; tea; therapeutics; thirst; tyrosine; China
- Abstract:
- ... Imatinib, the prototype BCR‐ABL tyrosine kinase inhibitor (TKI), is the first‐line treatment for Philadelphia chromosome‐positive chronic myeloid leukemia (CML) in the chronic phase. However, a subgroup of patients exhibit poor response or experience relapse. This issue may be overcome by combination therapy using natural compounds. Neferine, a major bisbenzylisoquinoline alkaloid extracted from “ ...
- DOI:
- 10.1111/1750-3841.14484
- https://doi.org/10.1111/1750-3841.14484
- Author:
- Lei XIONG; Chang-Fa CHEN; Tao-Ling MIN; Hai-Feng HU
- Source:
- Chinese journal of natural medicines 2019 v.17 no.2 pp. 155-160
- ISSN:
- 1875-5364
- Subject:
- Chromobacterium violaceum; Oriental traditional medicine; antineoplastic activity; culture media; cytotoxicity; dipeptides; human cell lines; humans; inhibitory concentration 50; neoplasm cells; nuclear magnetic resonance spectroscopy
- Abstract:
- ... Romipeptides A and B (1 and 2), two new romidepsin derivatives, and three known compounds, chromopeptide A (3), romidepsin (4) and valine-leucine dipeptide (5) were isolated from the fermentation broth of Chromobacterium violaceum No. 968. Their structures were elucidated by interpretation of their UV, HR-ESI-MS and NMR spectra. The absolute configuration of compound 1 and 2 were established by si ...
- DOI:
- 10.1016/S1875-5364(19)30018-4
- https://doi.org/10.1016/S1875-5364(19)30018-4
- Author:
- Peng-Cheng LIN; Lin-Lin JI; Xiang-Jian ZHONG; Jin-Jie LI; Xin WANG; Xiao-Ya SHANG; Sheng LIN
- Source:
- Chinese journal of natural medicines 2019 v.17 no.1 pp. 22-26
- ISSN:
- 1875-5364
- Subject:
- Cirsium arvense; Oriental traditional medicine; animal ovaries; antineoplastic activity; cell lines; chemical structure; colorectal neoplasms; cytotoxicity; food plants; humans; inhibitory concentration 50; ovarian neoplasms; secretion; spectral analysis; triterpenoids; tumor necrosis factor-alpha
- Abstract:
- ... Guided by TNF-α secretion inhibitory activity assay, four taraxastane-type triterpenoids, including two new ones, 22-oxo-20-taraxasten-3β, 30-diol (1) and 22α-hydroxy-20-taraxasten-30β, 30-triol (2), have been obtained from an active fraction of the petroleum ether-soluble extract of the the medicinal and edible plant Cirsium setosum. Their structures were elucidated by spectroscopic data and CD d ...
- DOI:
- 10.1016/S1875-5364(19)30005-6
- https://doi.org/10.1016/S1875-5364(19)30005-6
- Author:
- Quang‐Ung Le; Horng‐Liang Lay; Ming‐Chang Wu
- Source:
- Journal of food biochemistry 2019 v.43 no.2 pp. e12718
- ISSN:
- 0145-8884
- Subject:
- 2,2-diphenyl-1-picrylhydrazyl; Cymbopogon flexuosus; Oriental traditional medicine; aerial parts; antineoplastic activity; antioxidant activity; antioxidants; apoptosis; candy; caspase-3; caspase-9; chemical structure; cough; cytotoxicity; diet; ethanol; flavonoids; food industry; inhibitory concentration 50; liver; lung neoplasms; nuclear magnetic resonance spectroscopy; pharyngitis; secondary metabolites; skin diseases; spectral analysis; spices; Vietnam
- Abstract:
- ... This study investigated bioactive secondary metabolites from the aerial parts of Cymbopogon flexuosus (CF). Total phenolic and total flavonoid contents, the antioxidant activities including 2, 2′‐azino‐bis (3‐ethylbenzthiazoline‐6‐sulfonic acid) (ABTS⁺) and 2, 2′‐diphenyl‐1‐picrylhydrazyl (DPPH) radical scavenging systems, and cytotoxic effects were determined. 1, 3‐O‐di‐E‐caffeoylglycerol (SA3) a ...
- DOI:
- 10.1111/jfbc.12718
- https://doi.org/10.1111/jfbc.12718