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- Chen, Yang, et al. Show all 13 Authors
- Journal of proteome research 2019 v.18 no.5 pp. 2065-2077
- acids; bone marrow; carbon; ceramides; chemical bonding; humans; lipid metabolism; mesenchymal stromal cells; osteoporosis; phosphatidylcholines; phosphatidylethanolamines; phosphatidylglycerols; phosphatidylinositols; phosphatidylserines; principal component analysis; proteome; sphingomyelins; sphingosine; transcriptomics
- ... Aberrant differentiations of bone mesenchymal stem cells (BMSCs) have proved to be associated with the occurrence of senile osteoporosis. However, mechanisms of this phenomenon relative to abnormal lipid metabolism remain unclear. This study was conducted to characterize the lipidomics alterations during BMSC passaging, aiming at uncovering the aging-related lipid metabolism that may play an impor ...