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- Bresnahan, Caitlin G.; Taylor-Edinbyrd, Kiara A.; Cleveland, Alexander H.; Malone, Joshua A.; Dange, Nitin S.; Milet, Anne; Kumar, Revati; Kartika, Rendy
- Journal of organic chemistry 2019 v.84 no.11 pp. 7166-7174
- regioselectivity, etc ; Lewis acids; Lewis bases; cations; chemical reactions; chemical structure; computational methodology; indoles; organic chemistry; reaction mechanisms; Show all 10 Subjects
- ... Our investigations on the reaction mechanism to account for regioselectivity on the addition of indoles to unsymmetrical silyloxyallyl cations are reported. Using both experimental and computational methods, we confirmed the significance of steric effects from the silyl ether group toward directing the inward approach of indoles, leading to nucleophilic attack at the less substituted electrophilic ...
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