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1. Monascus yellow, red and orange pigments from red yeast rice ameliorate lipid metabolic disorders and gut microbiota dysbiosis in Wistar rats fed on a high-fat diet

Author:
Hong, Jiali,   et al.   ; ZhouThese authors contributed equally to this study., Wenbin; Guo, Rui; Guo, Weiling; Li, Lu; Ni, Li; Sun, Jinyuan; Liu, Bin; Rao, Pingfan; Lv, Xucong;     Show all 10 Authors
Source:
Food & function 2019 v.10 no.2 pp. 1073-1084
ISSN:
2042-650X
Subject:
Clostridium; Monascus; Ruminococcus albus; animal models; bile acids; blood lipids; blood serum; cholesterol; cholesterol metabolism; dysbiosis; excretion; functional foods; gene expression; genes; high fat diet; homeostasis; hyperlipidemia; ingredients; intestinal microorganisms; laboratory animals; messenger RNA; oral administration; phylotype; pigments; rats; red yeast rice; triacylglycerols
Abstract:
... This study aimed to compare the hypolipidaemic activities of different Monascus pigments (yellow, red and orange pigments) and elucidate their possible regulatory mechanisms on lipid and cholesterol metabolism in rats fed on a high-fat diet (HFD). Results showed that oral administrations of Monascus yellow, red and orange pigments can markedly alleviate the disturbance of lipid metabolism through ...
DOI:
10.1039/c8fo02192a