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You searched for: Author "Xia, Hong" Remove constraint Author: "Xia, Hong" Publication Year 2019 Remove constraint Publication Year: 2019 Subject humans Remove constraint Subject: humans Text Availability Citation in PubAg Remove constraint Text Availability: Citation in PubAg
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1. CD8 T cell-derived perforin aggravates secondary spinal cord injury through destroying the blood-spinal cord barrier

Author:
Xia, Hong,   et al.   ; Liu, Zhaoxiang; Zhang, Hua; Wang, Baocheng; Zhang, Renwen; Zeng, Qun; Guo, Lingzhi; Shen, Kui; Wang, BaTa; Zhong, Yanheng; Li, Zhizhong; Sun, Guodong;     Show all 12 Authors
Source:
Biochemical and biophysical research communications 2019 v.512 no.2 pp. 367-372
ISSN:
0006-291X
Subject:
CD8-positive T-lymphocytes; animal injuries; animal models; biotin; cerebrospinal fluid; cytokines; enzyme-linked immunosorbent assay; flow cytometry; humans; infectious diseases; inflammation; mice; permeability; spinal cord; staining
Abstract:
... Perforin plays an important role in autoimmune and infectious diseases, but its function in immune inflammatory responses after spinal cord injury (SCI) has received insufficient attention. The goal of this study is to determine the influence of perforin after spinal cord injury (SCI) on secondary inflammation. Compared recovery from SCI in perforin knockout (Prf1−/−) and wild-type(WT)mice, WT mic ...
DOI:
10.1016/j.bbrc.2019.03.002

2. Choline, not folate, can attenuate the teratogenic effects ofdibutyl phthalate (DBP) during early chick embryo development

Author:
Xia, Hong-Fei,   et al.   ; Wang, Rui; Sun, Da-Guang; Song, Ge; Guan, Chun Yi; Cui, Yi; Ma, Xu;     Show all 7 Authors
Source:
Environmental science and pollution research international 2019 v.26 no.29 pp. 29763-29779
ISSN:
0944-1344
Subject:
abnormal development; amniotic fluid; animal experimentation; apoptosis; chick embryos; chickens; choline; dibutyl phthalate; embryogenesis; enzyme-linked immunosorbent assay; folic acid; gas chromatography-mass spectrometry; humans; malondialdehyde; metabolites; neural tube defects; oxidation; oxidative stress; pollutants; reactive oxygen species; superoxide dismutase; teratogenicity; urine
Abstract:
... Dibutyl phthalate (DBP), a persistent environmental pollutant, can induce neural tube abnormal development in animals. The possible effects of DBP exposure on human neural tube defects (NTDs) remain elusive. In this study, the distribution of DBP in the body fluid of human NTDs was detected by GC-MS. Then, chick embryos were used to investigate the effects of DBP on early embryonic development. Ox ...
DOI:
10.1007/s11356-019-06087-w