Jump to Main Content
Did you mean to type: brian?
- Dickinson, Bryan C., et al. Show all 6 Authors
- Cell 2019 v.178 no.1 pp. 122-134.e12
- CRISPR-Cas systems; RNA; humans; nucleases; protein engineering; proteins
- ... Epitranscriptomic regulation controls information flow through the central dogma and provides unique opportunities for manipulating cells at the RNA level. However, both fundamental studies and potential translational applications are impeded by a lack of methods to target specific RNAs with effector proteins. Here, we present CRISPR-Cas-inspired RNA targeting system (CIRTS), a protein engineering ...