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- Author:
- Zhang, He; Nan, Fulong; Li, Zhuoxin; Zhao, Guanyu; Xie, Changzhan; Ha, Zhuo; Zhang, Jinyong; Han, Jicheng; Xiao, Pengpeng; Zhuang, Xinyu; Wang, Wei; Ge, Jinying; Tian, Mingyao; Lu, Huijun; Bu, Zhigao; Jin, Ningyi
- Source:
- Veterinary microbiology 2019 v.239 pp. 108490
- ISSN:
- 0378-1135
- Subject:
- Avian orthoavulavirus 1; Porcine reproductive and respiratory syndrome virus; cell-mediated immunity; chick embryos; genetic stability; industry; interferon-gamma; mice; neutralizing antibodies; pathogenicity; porcine reproductive and respiratory syndrome; poultry; proteins; reverse genetics; swine; tissues; vaccination; vaccines; viral load
- Abstract:
- ... Highly pathogenic porcine reproductive and respiratory syndrome (HP-PRRS) poses a significant threat to the pig industry, for which vaccination is considered to be an effective means of prevention and control. Here, we developed two recombinant Newcastle disease virus (NDV) LaSota-vectored PRRS candidate vaccines, rLaSota-GP5 and rLaSota-GP3-GP5, using reverse genetic techniques. The two recombina ...
- DOI:
- 10.1016/j.vetmic.2019.108490
-
https://dx.doi.org/10.1016/j.vetmic.2019.108490
- Author:
- Abozeid, Hassanein H.; Paldurai, Anandan; Varghese, Berin P.; Khattar, Sunil K.; Afifi, Manal A.; Zouelfakkar, Sahar; El-Deeb, Ayman H.; El-Kady, Magdy F.; Samal, Siba K.
- Source:
- Veterinary research 2019 v.50 no.1 pp. 12
- ISSN:
- 1297-9716
- Subject:
- Newcastle disease; protein synthesis; glycoproteins; live vaccines; infectious bronchitis; Western blotting; White Leghorn; Avian orthoavulavirus 1; viruses; Infectious bronchitis virus; viral shedding; vaccination; chicks; virulence; fluorescent antibody technique; signs and symptoms (animals and humans); poultry industry; Egypt; Middle East
- Abstract:
- ... Infectious bronchitis virus (IBV) causes a major disease problem for the poultry industry worldwide. The currently used live-attenuated vaccines have the tendency to mutate and/or recombine with circulating field strains resulting in the emergence of vaccine-derived variant viruses. In order to circumvent these issues, and to develop a vaccine that is more relevant to Egypt and its neighboring cou ...
- DOI:
- 10.1186/s13567-019-0631-5
- PubMed:
- 30744668
- PubMed Central:
- PMC6371441
-
https://dx.doi.org/10.1186/s13567-019-0631-5
- Author:
- Nikbakht Brujeni, Gholamreza; Hassanzadeh, Mohammad; Al-Karagoly, Hassan; Tolouei, Tohid; Esmailnejad, Atefeh
- Source:
- Acta veterinaria scandinavica 2019 v.61 no.1 pp. 41
- ISSN:
- 1751-0147
- Subject:
- Avian orthoavulavirus 1; Meleagris gallopavo; Newcastle disease; antibodies; antibody formation; biological half-life; blood serum; enzyme-linked immunosorbent assay; hemagglutination; humoral immunity; hybrids; immunoglobulin A; immunoglobulin Y; maternal immunity; poults; rearing; vaccination; vaccines
- Abstract:
- ... BACKGROUND: Villegas-Glisson/University of Georgia (VG/GA) strain of Newcastle disease virus (NDV) is recommended for the initial vaccination of commercially reared turkey poults. However, the vaccine-induced antibody responses have not been studied in this species. The level of systemic humoral immune responses against the NDV was investigated in commercial turkey poults vaccinated with the VG/GA ...
- DOI:
- 10.1186/s13028-019-0476-y
- PubMed:
- 31455410
- PubMed Central:
- PMC6712772
-
https://dx.doi.org/10.1186/s13028-019-0476-y
- Author:
- Habib, Momena; Yaqub, Tahir; Aziz-ul-Rahman,; Sohail, Tayyebah; Shahbaz, Muhammad; Shehzad, Wasim; Munir, Muhammad; Shabbir, Muhammad Zubair
- Source:
- Microbial pathogenesis 2019 v.137 pp. 103785
- ISSN:
- 0882-4010
- Subject:
- Anas platyrhynchos; Avian orthoavulavirus 1; Newcastle disease; RNA; cecum; chickens; diarrhea; disease outbreaks; disease surveillance; genes; genomics; hemorrhage; migratory birds; monitoring; mortality; necropsy; phylogeny; proventriculus; signs and symptoms (animals and humans); subgenotype; tissue tropism; tonsils; vaccination; viruses; waterfowl
- Abstract:
- ... Newcastle disease (ND), caused by Avian orthoavulavirus 1 (AOAV-1), affects multiple avian species around the globe. Frequent disease outbreaks are not uncommon even in vaccinates despite routine vaccination and, in this regards, viruses of diverse genotypes originating from natural reservoirs (migratory waterfowls) play an important role in a disease endemic setting. Though genomic characterizati ...
- DOI:
- 10.1016/j.micpath.2019.103785
-
https://dx.doi.org/10.1016/j.micpath.2019.103785
- Author:
- Pauly, Maude; Snoeck, Chantal J.; Phoutana, Vannaphone; Keosengthong, Amphone; Sausy, Aurélie; Khenkha, Latdavone; Nouanthong, Phonethipsavanh; Samountry, Bounthome; Jutavijittum, Prapan; Vilivong, Keooudomphone; Hübschen, Judith M.; Black, Antony P.; Pommasichan, Sisavath; Muller, Claude P.
- Source:
- Avian pathology 2019 v.48 no.6 pp. 503-511
- ISSN:
- 1465-3338
- Subject:
- Avian orthoavulavirus 1; Chicken anemia virus; DNA; Infectious bronchitis virus; Newcastle disease; RNA; animal viruses; antibodies; breeding sites; chickens; cloaca; ducks; enzyme-linked immunosorbent assay; farms; host range; pathogenicity; phylogeny; polymerase chain reaction; rearing; vaccination; virus transmission; viruses; Laos
- Abstract:
- ... In backyard farms of Lao People’s Democratic Republic, mixed-species rearing of poultry is a breeding-ground for cross-species transmission. Here, the epidemiology of viruses circulating among backyard poultry in Vientiane Province was assessed to guide future control strategies. Oral/tracheal and cloacal swabs, collected from 605 poultry (308 ducks, 297 chickens) between 2011 and 2015, were scree ...
- DOI:
- 10.1080/03079457.2019.1628919
-
http://dx.doi.org/10.1080/03079457.2019.1628919
- Author:
- Zegpi, R. A.; He, L.; Yu, Q.; Joiner, K. S.; van Santen, V. L.; Toro, H.
- Source:
- Avian diseases 2019 v.64 no.1 pp. 53-59
- ISSN:
- 0005-2086
- Subject:
- Avian orthoavulavirus 1; Infectious bronchitis virus; antibodies; antibody formation; chickens; enzyme-linked immunosorbent assay; hemagglutination; infectious bronchitis; respiratory system; signs and symptoms (animals and humans); vaccination; vaccines; viral load; virulence; viruses
- Abstract:
- ... Recombinant Newcastle disease virus (NDV) LaSota (LS) expressing secreted trimeric spike (S)-ectodomain (Se) of infectious bronchitis virus (IBV) (rLS/IBV.Se) was developed and evaluated for protection conferred against IBV challenge. The IBV S-ectodomain protein, which is S excluding the transmembrane anchor and short cytoplasmic domain of S2, expressed from recombinant LS corresponds to an Arkan ...
- DOI:
- 10.1637/0005-2086-64.1.53
-
http://dx.doi.org/10.1637/0005-2086-64.1.53
- Author:
- Moharam, Ibrahim; Razik, Alaa Abd el; Sultan, Hesham; Ghezlan, Mohammed; Meseko, Clement; Franzke, Kati; Harder, Timm; Beer, Martin; Grund, Christian
- Source:
- Avian pathology 2019 v.48 no.5 pp. 406-415
- ISSN:
- 1465-3338
- Subject:
- Avian orthoavulavirus 1; Infectious bronchitis virus; Influenza A virus; Newcastle disease; animal viruses; birds; cell culture; diagnostic techniques; distress; farms; genes; mixed infection; mortality; pathotypes; phylogeny; poultry; quantitative polymerase chain reaction; reverse transcriptase polymerase chain reaction; signs and symptoms (animals and humans); vaccination; vaccines; viral load; virulence; virus transmission; viruses; Egypt
- Abstract:
- ... Highly contagious Newcastle disease (ND) is associated with devastating outbreaks with highly variable clinical signs among gallinaceous birds. In this study we aimed to verify clinical ND suspicions in poultry holdings in Egypt suffering from respiratory distress and elevated mortality, comparing two groups of ND-vaccinated poultry holdings in three governorates. Besides testing for Newcastle dis ...
- DOI:
- 10.1080/03079457.2019.1612852
-
http://dx.doi.org/10.1080/03079457.2019.1612852
- Author:
- Roy Chowdhury, Ishita; Yeddula, Sai Goutham Reddy; Pierce, Brian G.; Samal, Siba K.; Kim, Shin-Hee
- Source:
- Vaccine 2019 v.37 no.35 pp. 4956-4962
- ISSN:
- 0264-410X
- Subject:
- Avian orthoavulavirus 1; Orthorubulavirus; avian influenza; broiler chickens; consensus sequence; mortality; poults; proteins; secondary immunization; turkeys; vaccination; vaccines; viruses; North America
- Abstract:
- ... Continuous outbreaks of highly pathogenic avian influenza (HPAI) viruses in commercial poultry have caused devastating losses to domestic poultry with a raising public health concern. The outbreaks of HPAI viruses have increased worldwide, including the North America. Therefore, vaccination has been considered as an alternative strategy for an efficient control of HPAI viruses. In this study, we a ...
- DOI:
- 10.1016/j.vaccine.2019.07.028
-
https://dx.doi.org/10.1016/j.vaccine.2019.07.028
- Author:
- Msoffe, Peter L. M.; Chiwanga, Gaspar H.; Cardona, Carol J.; Miller, Patti J.; Suarez, David L.
- Source:
- Avian diseases 2019 v.63 no.4 pp. 634-640
- ISSN:
- 0005-2086
- Subject:
- Avian orthoavulavirus 1; Influenza A virus; Newcastle disease; antibodies; biosecurity; cages; chickens; enzyme-linked immunosorbent assay; farmers; farms; fomites; genotype; markets; monitoring; nucleotide sequences; risk; serology; signs and symptoms (animals and humans); vaccination; vaccines; villages; virulence; viruses; Botswana; Europe; Kenya; Mozambique; South Africa; Tanzania; Uganda
- Abstract:
- ... Chickens in live bird markets (LBMs) from six different regions of Tanzania were surveyed for Newcastle disease (ND) virus (NDV) and avian influenza virus in 2012. ELISA-based serology, virus isolation, and characterization, including pathotyping was conducted. Virulent NDV was isolated from almost 10% of the tested samples, with two distinct genotypes being detected. One genotype was similar to r ...
- DOI:
- 10.1637/aviandiseases-D-19-00089
-
http://dx.doi.org/10.1637/aviandiseases-D-19-00089
- Author:
- Awad, N.F.S.; Abd El‐Hamid, M.I.; Hashem, Y.M.; Erfan, A.M.; Abdelrahman, B.A.; Mahmoud, H.I.
- Source:
- Journal of applied microbiology 2019 v.127 no.2 pp. 396-405
- ISSN:
- 1364-5072
- Subject:
- Avian orthoavulavirus 1; Escherichia coli; Mycoplasma gallisepticum; antibodies; bacterial infections; biosecurity; broiler chickens; enzyme-linked immunosorbent assay; gene expression regulation; genes; hemagglutination inhibition test; humoral immunity; immune response; immunoglobulin G; immunosuppression; interferons; interleukin-4; interleukin-6; mixed infection; pathogens; poultry diseases; reverse transcriptase polymerase chain reaction; vaccination; vaccines
- Abstract:
- ... AIMS: This study was designed to investigate, in an in vivo setting, the effects of single and combined infections with either Mycoplasma gallisepticum (MG) and/or Escherichia coli on the chicken immune response induced by Newcastle disease virus (NDV) vaccine. METHODS AND RESULTS: Humoral immunity was measured through detection of NDV antibody and anti‐NDV IgG titres using haemagglutination‐inhib ...
- DOI:
- 10.1111/jam.14303
-
http://dx.doi.org/10.1111/jam.14303
- Author:
- Hassanin, Ola; Abdallah, Fatma; Mohamed, Mahmoud H.A.; Abdel Fattah, Doaa M.
- Source:
- Veterinary microbiology 2019 v.235 pp. 248-256
- ISSN:
- 0378-1135
- Subject:
- Avian orthoavulavirus 1; B-lymphocytes; Mardivirus; Marek disease; T-lymphocytes; chickens; cytokines; dose response; genes; humoral immunity; immune response; innate immunity; interferon-alpha; melanoma; models; serotypes; signal transduction; vaccination; viral vaccines; virulence
- Abstract:
- ... Marek’s disease virus (MDV) leads to a lytic infection of B-lymphocytes in chickens, and also latently infects T-lymphocytes. Although Marek’s disease vaccines have been widely in use, little is known about the innate immune response of this important livestock vaccine. In this study, we tested the effect of different commercially applied Marek’s disease vaccines on the expression pattern of selec ...
- DOI:
- 10.1016/j.vetmic.2019.07.008
-
https://dx.doi.org/10.1016/j.vetmic.2019.07.008
- Author:
- El-Aried, Tamer A.; Mansour, Shimaa M. G.; ElBakrey, Reham M.; N. Ismail, Abd El-Shakour; Eid, Amal A. M.
- Source:
- Avian diseases 2019 v.63 no.4 pp. 606-618
- ISSN:
- 0005-2086
- Subject:
- Avian orthoavulavirus 1; Infectious bursal disease virus; Influenza A virus; Newcastle disease; amino acids; avian influenza; broiler chickens; etiological agents; farms; financial economics; flocks; hemagglutination; immunosuppression; infectious bursal disease; live vaccines; monitoring; mutation rate; peptides; phylogeny; poultry industry; serology; vaccination; vaccine development; virulence; viruses; Egypt
- Abstract:
- ... Infectious bursal disease (IBD) virus (IBDV) is the causative agent of a highly contagious and immunosuppressive disease of chickens with huge economic losses to the poultry industry despite extensive vaccination. Analysis of isolated IBDV field strains from vaccinated birds would greatly improve the current immunization regimens and support the development of vaccines that offer better immunity. ...
- DOI:
- 10.1637/aviandiseases-D-19-00086
-
http://dx.doi.org/10.1637/aviandiseases-D-19-00086
- Author:
- Zhang, Guihua; Qu, Yajin; Niu, Yujuan; Zhang, Huixia; Sun, Qinqin; Liu, Xingpo; Li, Yue; Zhang, Hui; Liu, Mengda
- Source:
- Poultry science 2019 v.98 no.7 pp. 2772-2780
- ISSN:
- 1525-3171
- Subject:
- Avian leukosis virus; Avian orthoavulavirus 1; Influenza A virus; antigens; body weight; broiler breeders; carcinogenicity; chick embryos; gene expression; genes; genetic background; hemangioma; laying hens; liver; lungs; messenger RNA; mortality; pathogenicity; vaccination
- Abstract:
- ... Avian leukosis virus subgroup J has been found to infect many types of chickens with various genetic backgrounds. The ALV-J strain NX0101, which was isolated from broiler breeders in 2001, mainly induces the formation of myeloid cell tumors. However, strain HN10PY01, which was recently isolated from laying hens, mainly induces the formation of myeloid cell tumors and hemangioma. In order to determ ...
- DOI:
- 10.3382/ps/pez065
-
http://dx.doi.org/10.3382/ps/pez065
- Author:
- Agbehadzi, R K; Hamidu, J A; Adomako, K; Enu, R
- Source:
- Poultry science 2019 v.98 no.6 pp. 2399-2404
- ISSN:
- 1525-3171
- Subject:
- Avian orthoavulavirus 1; Infectious bursal disease virus; antibodies; body weight changes; broiler chickens; chicks; data analysis; diet; feed conversion; feed intake; hatcheries; head; hemagglutination inhibition test; maternal immunity; mortality; neck; supply chain; vaccination; Ghana
- Abstract:
- ... This research evaluates the effectiveness of local hatcheries in producing quality broiler day-old chicks in Ghana. A total of 600 Cobb 500 unsexed day-old broiler chicks obtained from 3 local hatcheries were raised for 6 wk with recommended starter and finisher diets from a registered source. The parameters measured included feed intake, body weights, body weight gain, feed conversion ratio, perc ...
- DOI:
- 10.3382/ps/pez020
-
http://dx.doi.org/10.3382/ps/pez020
- Author:
- Absalón, A. E.; Cortés-Espinosa, Diana V.; Lucio, E.; Miller, P. J.; Afonso, C. L.
- Source:
- Tropical animal health and production 2019 v.51 no.5 pp. 1033-1048
- ISSN:
- 0049-4747
- Subject:
- Newcastle disease; poultry industry; vaccines; Avian orthoavulavirus 1; molecular epidemiology; indigenous species; vaccination; wild birds; virulence; poultry; Venezuela; Colombia; Latin America; Mexico; Peru
- Abstract:
- ... Newcastle disease (ND) infects wild birds and poultry species worldwide, severely impacting the economics of the poultry industry. ND is especially problematic in Latin America (Mexico, Colombia, Venezuela, and Peru) where it is either endemic or re-emerging. The disease is caused by infections with one of the different strains of virulent avian Newcastle disease virus (NDV), recently renamed Avia ...
- Handle:
- 10113/6444425
- DOI:
- 10.1007/s11250-019-01843-z
- PubMed:
- 30877525
- PubMed Central:
- PMC6520322
-
https://dx.doi.org/10.1007/s11250-019-01843-z
- Author:
- Sedeik, M E; Elbestawy, A R; El-shall, N A; Abd El-Hack, M E; Saadeldin, I M; Swelum, A A
- Source:
- Poultry science 2019 v.98 no.5 pp. 2000-2007
- ISSN:
- 1525-3171
- Subject:
- Avian orthoavulavirus 1; Newcastle disease; body weight changes; broiler chickens; cell-mediated immunity; cloaca; diarrhea; flocks; genotype; hemagglutination; inactivated vaccines; interferon-gamma; interleukin-6; mortality; vaccination; viral shedding
- Abstract:
- ... Newcastle disease is still causing huge economic losses and devastating outbreaks in poultry flocks despite implementation of extensive vaccination programs. Five commercial broiler chicken groups were established as G1 (non-vaccinated, non-challenged group) and G2 (non-vaccinated, challenged group), and 3 vaccinated challenged groups as G3 (vaccinated with heterologous inactivated Newcastle disea ...
- DOI:
- 10.3382/ps/pey559
-
http://dx.doi.org/10.3382/ps/pey559
- Author:
- Ding, Leilei; Chen, Pucheng; Bao, Xingzhi; Li, Aixin; Jiang, Yongping; Hu, Yuzhen; Ge, Jinying; Zhao, Yubo; Wang, Bo; Liu, Jinxiong; Chen, Hualan
- Source:
- Veterinary microbiology 2019 v.232 pp. 146-150
- ISSN:
- 0378-1135
- Subject:
- chickens; specific pathogen-free animals; morbidity; poultry diseases; Avian orthoavulavirus 1; genes; recombinant vaccines; vaccination; virulence; mortality; Anatid alphaherpesvirus 1
- Abstract:
- ... Newcastle disease virus (NDV) is a major threat to poultry worldwide. Virulent Newcastle disease virus infection can cause 100% morbidity and mortality in chickens. Vaccination is the most effective way to prevent and control NDV outbreaks in poultry. Previously, we demonstrated that a duck enteritis virus (DEV) vaccine strain is a promising vector to generate recombinant vaccines in chickens. Her ...
- DOI:
- 10.1016/j.vetmic.2019.04.022
-
https://dx.doi.org/10.1016/j.vetmic.2019.04.022
- Author:
- Horst, G; Levine, R; Chick, R; Hofacre, C
- Source:
- Poultry science 2019 v.98 no.4 pp. 1643-1647
- ISSN:
- 1525-3171
- Subject:
- Avian orthoavulavirus 1; Infectious bronchitis virus; beta-glucans; broiler chickens; chicks; feed supplements; hatcheries; immunity; infectious bursal disease; vaccination; vaccines
- Abstract:
- ... This 42-day study evaluated the effects of dietary supplementation with β-1,3-glucan (Aleta™) on the vaccination response to Newcastle disease virus (NDV), avian infectious bronchitis virus (IBV), and infectious bursal disease (IBD) in a non-challenged environment. This trial included 600 chicks (all vaccinated with IBD at the hatchery) which were assigned to 1 of 3 treatments: vaccination (NDV, I ...
- DOI:
- 10.3382/ps/pey523
-
http://dx.doi.org/10.3382/ps/pey523
- Author:
- Bu, Ya-wen; Yang, Hui-ming; Jin, Ji-hui; Zhao, Jing; Xue, Jia; Zhang, Guo-zhong
- Source:
- Avian pathology 2019 v.48 no.2 pp. 91-97
- ISSN:
- 1465-3338
- Subject:
- chickens; Newcastle disease; specific pathogen-free animals; chicken eggs; morbidity; vaccines; Avian orthoavulavirus 1; viruses; genotype; reverse genetics; vaccination; death; virulence; mortality
- Abstract:
- ... Intensive vaccination strategies against Newcastle disease (ND) have been implemented in many countries for a long time, but ND outbreaks still occur frequently, with most isolates belonging to genotype VII of Newcastle disease virus (NDV). Many researchers have revealed that vaccines closely matched to epidemic viruses provide better protection. Therefore, using a previously established reverse g ...
- DOI:
- 10.1080/03079457.2018.1548754
-
https://dx.doi.org/10.1080/03079457.2018.1548754
- Author:
- Purswell, J L; Branton, S L; Evans, J D
- Source:
- The Journal of applied poultry research 2019 v.28 no.1 pp. 215-220
- ISSN:
- 1537-0437
- Subject:
- Avian orthoavulavirus 1; Infectious bronchitis virus; automation; biosecurity; disease prevention; flocks; prototypes; pullets; seroconversion; sprayers; spraying; vaccination
- Abstract:
- ... Recent catastrophic disease events have highlighted the need for improved disease prevention measures. Improved biosecurity and vaccination programs can aid in reducing animal population and economic losses. Performance of a prototype automated whole-house spray vaccination system was evaluated over 3 flocks in a commercial breeder pullet house. Birds were spray vaccinated for infectious bronchiti ...
- DOI:
- 10.3382/japr/pfy060
-
http://dx.doi.org/10.3382/japr/pfy060
- Author:
- Esmaelizad, Majid; Mayahi, Vafa
- Source:
- Archives of virology 2019 v.164 no.3 pp. 717-724
- ISSN:
- 0304-8608
- Subject:
- bioinformatics; Avian orthoavulavirus 1; genes; wild birds; vaccination; computer software; hybrids; financial economics; viruses; genotype; conserved sequences; pathogenicity; immune response; markets; trade; genomics; nucleotide sequences; evolutionary adaptation; selection pressure; Middle East; Asia
- Abstract:
- ... Adaptation and evolution of avian avulavirus 1, or Newcastle disease virus (NDV), has led to tremendous economic losses worldwide. The occurrence of natural recombination and selection pressure has been traced for NDV based on a few recent reports, but a dominant pattern based on genomic characteristics is lacking. Here, we used bioinformatics tools to search for evidence of recombination in all o ...
- DOI:
- 10.1007/s00705-018-04130-8
-
https://dx.doi.org/10.1007/s00705-018-04130-8
- Author:
- Haji-Abdolvahab, Habibbolah; Ghalyanchilangeroudi, Arah; Bahonar, Alireza; Ghafouri, Seyed Ali; Vasfi Marandi, Mehdi; Mehrabadi, Mohammad Hosein Fallah; Tehrani, Farshad
- Source:
- Tropical animal health and production 2019 v.51 no.3 pp. 689-695
- ISSN:
- 0049-4747
- Subject:
- anamorphs; broiler chickens; Newcastle disease; monitoring; flocks; serotypes; farms; infectious bronchitis; surveys; Avian orthoavulavirus 1; viruses; avian influenza; Infectious bronchitis virus; vaccination; pathogens; Iran
- Abstract:
- ... In this study, the prevalence and spatial distribution of Newcastle disease, infectious bronchitis, and avian influenza have been evaluated in commercial broiler farms in 31 provinces in Iran. In this survey, a total of 233 affected broiler chicken farms were sampled. The infectious bronchitis virus (alone) was detected with highest frequency in 60 farms, and separately or combined with other agen ...
- DOI:
- 10.1007/s11250-018-1743-z
- PubMed:
- 30377950
- PubMed Central:
- PMC7088748
-
https://dx.doi.org/10.1007/s11250-018-1743-z
- Author:
- Mohebbi, Alireza; Ebrahimzadeh, Mir Saeed; Baghban Rahimi, Sanaz; Saeidi, Mohsen; Tabarraei, Alijan; Mohebbi, Seyed Reza; Shirian, Sadegh; Gorji, Ali; Ghaemi, Amir
- Source:
- Virus research 2019 v.261 pp. 72-80
- ISSN:
- 0168-1702
- Subject:
- adjuvants; secretion; interferon-gamma; Avian orthoavulavirus 1; genes; vaccination; interleukin-12; DNA; cell-mediated immunity; splenocytes; tumor necrosis factors; females; apoptosis; Human papillomavirus type 16; antigens; cytotoxicity; mice; proteins; carcinoma; ligands; recombinant vaccines; cytotoxic T-lymphocytes; interleukin-4
- Abstract:
- ... The potential of non-replicating Newcastle Disease Virus (NDV) as an adjuvant for DNA vaccination remains to be elucidated. To assess the therapeutic effects of DNA vaccine (HPV-16 E7 gene) adjuvanted with NDV, female C57/BL6 mice were inoculated with murine TC-1 cells of human papillomavirus (HPV)-related carcinoma, expressing human papillomavirus 16 (HPV-16) E6/E7 antigens, and immunized with DN ...
- DOI:
- 10.1016/j.virusres.2018.12.014
-
http://dx.doi.org/10.1016/j.virusres.2018.12.014
- Author:
- Das, Moushumee; Baro, Sangeeta; Kumar, Sachin
- Source:
- Virus research 2019 v.260 pp. 114-122
- ISSN:
- 0168-1702
- Subject:
- antimicrobial properties; chickens; drugs; vaccination; Avian orthoavulavirus 1; viruses; imidazoles; genetic variation; interferons
- Abstract:
- ... Despite recent progress in vaccination options, Newcastle disease virus (NDV) stands a severe global epidemic and economic burden. It is difficult to control NDV with vaccination alone due to its evolving genetic variability; therefore, an effective therapeutic must target to resist its replication and further evolution. Drug repurposing is a practical and economical method to develop therapeutics ...
- DOI:
- 10.1016/j.virusres.2018.11.013
-
https://dx.doi.org/10.1016/j.virusres.2018.11.013
- Author:
- Xu, Xiaohong; Ding, Zhuang; Yuan, Qianliang; Ding, Jiaxin; Li, Jindou; Wang, Weiqi; Cong, Yanlong; Ouyang, Wei; Wang, Yongshan; Qian, Jing; Yin, Renfu
- Source:
- Vaccine 2019 v.37 no.3 pp. 444-451
- ISSN:
- 0264-410X
- Subject:
- Newcastle disease; proteins; antigens; flocks; vaccines; virus-like particles; Avian orthoavulavirus 1; genotype; virulent strains; viral load; vaccination; viral shedding; commercialization; birds; poultry industry
- Abstract:
- ... Newcastle disease (ND) is one of the most severe avian infectious disease inflicting a great loss on poultry industry worldwide. The control of ND relies on proper vaccination strategies. The vaccine strains of Newcastle disease virus (NDV) mainly belong to genotype I, II or III, which cannot fully prohibit virus shedding against the prevalent genotype VII virulent strain attack. To develop a safe ...
- DOI:
- 10.1016/j.vaccine.2018.11.068
-
https://dx.doi.org/10.1016/j.vaccine.2018.11.068
- Author:
- Campbell, Zoë A.; Otieno, Linus; Shirima, Gabriel M.; Marsh, Thomas L.; Palmer, Guy H.
- Source:
- Vaccine 2019 v.37 no.1 pp. 11-18
- ISSN:
- 0264-410X
- Subject:
- Newcastle disease; livestock productivity; poultry production; burden of disease; Avian orthoavulavirus 1; willingness to pay; vaccination; contingent valuation; assets; risk management; cattle; developing countries; market prices; mortality; chickens; households; income; vaccines; surveys; villages; Tanzania
- Abstract:
- ... Vaccination can be an effective risk management approach to minimize the burden of disease and increase livestock productivity for smallholder households in low income countries. In contrast to vaccination of cattle, a high-value smallholder asset, there is a significant knowledge gap for the drivers of vaccine adoption of smallholder poultry. Newcastle disease virus (NDV) causes high mortality in ...
- DOI:
- 10.1016/j.vaccine.2018.11.058
- PubMed:
- 30478006
- PubMed Central:
- PMC6290109
-
https://dx.doi.org/10.1016/j.vaccine.2018.11.058
- Author:
- Xu, Xiaohong; Xue, Cong; Liu, Xinxin; Li, Junjiao; Fei, Yidong; Liu, Zhe; Mu, Jiaqi; Bi, Yuhai; Qian, Jing; Yin, Renfu; Ding, Zhuang
- Source:
- Veterinary microbiology 2019 v.228 pp. 173-180
- ISSN:
- 0378-1135
- Subject:
- Newcastle disease; immunoglobulin A; Avian orthoavulavirus 1; genes; vaccination; open reading frames; antibodies; viruses; genotype; viral shedding; lethal dose; virulence; pathogens; flocks; hemagglutinins; prototypes; vaccine development; eggs; chickens; Influenza A virus; vaccines; avian influenza
- Abstract:
- ... Newcastle disease virus (NDV) and H9 subtype avian influenza virus (AIV) are two avian pathogens across the globe. Inasmuch as most poultry flocks worldwide are vaccinated with a live low-virulence or attenuated NDV vaccine, we embarked on the development of vaccine prototypes that would have dual specificities and would allow a single immunization against both avian influenza (AI) and Newcastle d ...
- DOI:
- 10.1016/j.vetmic.2018.11.006
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https://dx.doi.org/10.1016/j.vetmic.2018.11.006