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- Choi, Jung-Hye, et al. Show all 8 Authors
- Food and chemical toxicology 2019 v.124 pp. 101-111
- apoptosis; caspases; cell cycle checkpoints; cytochrome c; human cell lines; neoplasm cells; phosphorylation; protein synthesis; resveratrol; small interfering RNA; therapeutics; toxicology; transfection; uterine cervical neoplasms
- ... In this study, several resveratrol analogs were synthesized and evaluated in search of a more effective anti-proliferative resveratrol analog. Among the evaluated resveratrol analogs, we have identified N-(4-methoxyphenyl)-3,5-dimethoxybenamide (MPDB) as a potent anti-proliferative compound. Treatment with MPDB resulted in G2/M phase cell cycle arrest, which was accompanied by alteration of G2/M-r ...