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- Eyer, Joel, et al. Show all 3 Authors
- Chemosphere 2019 v.229 pp. 314-323
- DNA fragmentation; acetylcysteine; apoptosis; caspases; cell cycle; cell proliferation; cell viability; cytoskeleton; cytotoxicity; dose response; enzyme inhibitors; fungicides; genotoxicity; glioma; human health; inhibitory concentration 50; mechanism of action; mitochondria; nervous system; neurotoxicity; oxidative stress; risk; staining; triazoles
- ... Epoxiconazole (EPX) is a very effective fungicide of the triazole family. Given its wide spectrum of use, the increased application of this pesticide may represent a serious risk on human health. Previous studies have found that EPX is cytotoxic to cells, although the exact mechanism remains elusive. In particular, the effect on the nervous system is poorly elucidated. Here we evaluated the implic ...