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- Jeong, Gil‐Saeng, et al. Show all 5 Authors
- Phytotherapy research 2019 v.33 no.11 pp. 2948-2959
- Dalbergia odorifera; T-lymphocytes; actin; animal models; bone marrow; bone resorption; cathepsin K; cytoplasm; heartwood; humans; ligands; lipopolysaccharides; macrophages; mice; mitogen-activated protein kinase; monocytes; osteoblasts; osteoclasts; signal transduction; skeleton; transcription factor NF-kappa B
- ... The balance between the osteoblasts and the osteoclasts is important for the maintenance of the skeleton of the human body. The osteoclasts absorb bone after differentiated into polymorphonuclear cells by the fusion of monocytes/macrophages. We have found that 6,7,4′‐Trihydroxyflavone (THF), a compound from the heartwood of Dalbergia Odorifera inhibits receptor activator of NF‐κB ligand (RANKL)‐in ...
- Jeong, Gil-Saeng, et al. Show all 5 Authors
- Food and chemical toxicology 2019 v.132 pp. 110651
- Aloe; animal models; anthraquinones; antioxidant activity; blood serum; catalase; creatinine; death; enzyme activity; glutathione; glutathione peroxidase; glycosides; interleukin-6; kidneys; lipid peroxidation; mice; necrosis; neoplasms; nitric acid; nitric oxide synthase; protective effect; sepsis (infection); superoxide dismutase; surgery; tissues; transcription factor NF-kappa B; tumor necrosis factor-alpha; urea nitrogen; urine
- ... Aloin is the major anthraquinone glycoside obtained from the Aloe species and exhibits anti-inflammatory and anti-oxidative activities. However, the renal protective effects of aloin and underlying molecular mechanism remain unclear. This study was initiated to determine whether aloin could modulate renal functional damage in a mouse model of sepsis and to elucidate the underlying mechanisms. The ...