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- Jirintai, Suljid, et al. Show all 8 Authors
- Journal of virological methods 2019 v.270 pp. 1-11
- Hepatitis E virus; antiviral agents; cell culture; chronic diseases; drugs; hepatitis E; immunocompromised population; interferons; leukopenia; luciferase; patients; pregnancy; replicon; screening; thrombocytopenia; virus replication
- ... Hepatitis E, which is caused by hepatitis E virus (HEV), is generally a self-limiting, acute, and rarely fatal disease. It is sometimes fulminant and lethal, especially during pregnancy. Indeed, it occasionally takes a chronic course in immunocompromised individuals. To cure hepatitis E patients, the broad-spectrum antivirals (ribavirin and pegylated interferon α) are used. However, this treatment ...