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- Author:
- Lou, Jiatao, et al. ; Bai, Yanan; Qu, Youlan; Wu, Zhenhua; Ren, Yijiu; Cheng, Zule; Lu, Yunxing; Hu, Jie; Zhao, Jianlong; Chen, Chang; Mao, Hongju; Show all 11 Authors
- Source:
- Biosensors & bioelectronics 2019 v.142 pp. 111523
- ISSN:
- 0956-5663
- Subject:
- RNA; biomarkers; biopsy; biosensors; blood; detection limit; early diagnosis; genes; lung neoplasms; lungs; patients; quantitative polymerase chain reaction; t-test
- Abstract:
- ... Emerging evidence indicates that extracellular vesicle (EV) long non-coding ribonucleic acids (lncRNAs) in lung cancer may be clinically useful biomarkers for early diagnosis using liquid biopsy. However, the extremely low quantities of EV-lncRNAs in peripheral blood are a major challenge for multi-target detection. In this study, we developed a new multi-colour fluorescence digital PCR EV-lncRNA ...
- DOI:
- 10.1016/j.bios.2019.111523
-
https://dx.doi.org/10.1016/j.bios.2019.111523