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- Randle, Nadine, et al. Show all 11 Authors
- Cell and tissue research 2019 v.375 no.2 pp. 409-424
- Salmonella Typhimurium; Toxoplasma gondii; animal models; cattle; confocal microscopy; cryopreservation; epithelial cells; host-pathogen relationships; human population; humans; intestinal crypts; jejunum; morbidity; mortality; pathogens; renewable resources; rodents; slaughterhouses; staining; stem cells; swine; zoonoses
- ... The in vitro 3D culture of intestinal epithelium is a valuable resource in the study of its function. Organoid culture exploits stem cells’ ability to regenerate and produce differentiated epithelium. Intestinal organoid models from rodent or human tissue are widely available whereas large animal models are not. Livestock enteric and zoonotic diseases elicit significant morbidity and mortality in ...