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- Chitarra, Cristiane Silva; Oliveira Filho, João Xavier de; Morés, Nelson; Silva, Mayara Inácio Vincenzi da; Cândido, Stefhano Luis; Cezarino, Paula Gabriela; Nakazato, Luciano; Dutra, Valéria
- Microbial pathogenesis 2018 v.122 pp. 180-183
- Pasteurella multocida; RNA; amino acid metabolism; bacteria; biochemical pathways; gene expression; gene expression regulation; genes; heat stress; iron; lungs; nitrogen; pathogenesis; pathogens; pneumonia; ribosomal proteins; statistical analysis; swine; transcription (genetics); transcriptome; translation (genetics); virulence
- ... Pasteurella multocida is one of the most important pathogen that causes pneumonia in swine. Although several virulence factors are known, the pathogenesis of this bacterium is not well-studied. Therefore, to study the pathogenesis of P. multocida infection in porcine lung, next-generation RNA sequencing was used to compare the transcriptomes of P. multocida grown in vivo and in vitro, respectively ...
- Qian, Yunyun; Zhang, Yuhang; Yu, Yanfei; Li, Quan; Guo, Genglin; Fu, Yang; Yao, Huochun; Lu, Chengping; Zhang, Wei
- Microbial pathogenesis 2018 v.122 pp. 90-97
- Danio rerio; Streptococcus suis; Western blotting; bacterial adhesion; fluorescent antibody technique; homologous recombination; human cell lines; humans; mice; morbidity; mortality; mutants; pathogenesis; pathogens; phagocytosis; serotypes; swine; virulence
- ... Streptococcus suis serotype 2 (SS2) is an important zoonotic pathogen that infects swine and humans with high mortality and morbidity. Although a number of virulence-associated factors have been reported, the understanding of the molecular mechanism underlying SS2 pathogenicity remains limited. Our previous studies revealed that srtBCD-associated protein 2’ (SBP2′) contributed to the pathogenesis ...