Publication Year: 2018 / Source: 2018 v.52 no.13 / Subject: databases and Micropterus salmoides

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Author:: Basili, Danilo; Zhang, Ji-Liang; Herbert, John; Kroll, Kevin; Denslow, Nancy D.; Martyniuk, Christopher J.; Falciani, Francesco; Antczak, Philipp
Source:: Environmental science & technology 2018 v.52 no.13 pp. 7553-7565
ISSN:: 1520-5851
Subject:: Micropterus salmoides; animal ovaries; databases; dynamic models; endocrine-disrupting chemicals; environmental science; estradiol; females; fish communities; gene expression; gene expression regulation; genes; gonadosomatic index; liver; males; ovarian development; prediction; quantitative polymerase chain reaction; quercetin; transcription (genetics); transcriptomics; vitellogenin
Abstract:: ... In recent years, decreases in fish populations have been attributed, in part, to the effect of environmental chemicals on ovarian development. To understand the underlying molecular events we developed a dynamic model of ovary development linking gene transcription to key physiological end points, such as gonadosomatic index (GSI), plasma levels of estradiol (E2) and vitellogenin (VTG), in largemo ...
DOI:: 10.1021/acs.est.8b02805
: http://dx.doi.org/10.1021/acs.est.8b02805