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You searched for: Publication year rev 7982-2018 Remove constraint Publication year rev: 7982-2018 Subject DNA methylation Remove constraint Subject: DNA methylation Subject demethylation Remove constraint Subject: demethylation
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1. Analysis of sulphur and chlorine induced DNA cytosine methylation alterations in fresh corn (Zea mays L. saccharata and rugosa) leaf tissues by methylation sensitive amplification polymorphism (MSAP) approach

Author:
Tinashe Zenda; Songtao Liu; Daxuan Yao; Huijun Duan
Source:
Genes & genomics 2018 v.40 no.9 pp. 913-925
ISSN:
1976-9571
Subject:
DNA; DNA methylation; Zea mays; abiotic stress; chlorine; corn; crops; cultivars; cytosine; demethylation; filling period; genome; hybrids; leaves; loci; oligodeoxyribonucleotides; photosynthates; soil fertility; stress response; sulfur; tissues
Abstract:
... DNA (cytosine) methylation mechanism is another way through which plants respond to various cues including soil fertility amendments and abiotic stresses, and the mechanism has been used to infer some physiological, biochemical or adaptation processes. Despite numerous studies on global DNA methylation profiling in various crop species, however, researches on fresh corn (Zea mays L. saccharata or ...
DOI:
10.1007/s13258-018-0685-1

2. Bisphenol A: What lies beneath its induced diabetes and the epigenetic modulation?

Author:
Soheila Rahmani; Nazila Pour Khalili; Fazlullah Khan; Shokoufeh Hassani; Elmira Ghafour-Boroujerdi; Mohammad Abdollahi
Source:
Life sciences 2018 v.214 pp. 136-144
ISSN:
0024-3205
Subject:
DNA methylation; adipocytes; animals; bisphenol A; demethylation; endocrine-disrupting chemicals; epigenetics; estrogenic properties; fatty liver; genes; glucose; histones; homeostasis; insulin; islets of Langerhans; lipids; liver; microRNA; noninsulin-dependent diabetes mellitus; obesity; pollution; skeletal muscle; toxicity
Abstract:
... Nowadays, endocrine disrupting chemical pollution has become one of the major concerns due to the potential role of these chemicals in provoking endocrine disorders especially type 2 diabetes. As a widespread endocrine disrupting chemical, Bisphenol A, with modest estrogenic activity can exert its detrimental effects in the different organs involved in type 2 diabetes such as pancreas, liver, adip ...
DOI:
10.1016/j.lfs.2018.10.044

3. Brood size influences patterns of DNA methylation in wild Zebra Finches (Taeniopygia guttata)

Author:
Elizabeth L. Sheldon; Aaron W. Schrey; Alexandria K. Ragsdale; Simon C. Griffith
Source:
Auk 2018 v.135 no.4 pp. 1113-1122
ISSN:
1938-4254
Subject:
DNA methylation; Taeniopygia guttata; adults; blood; demethylation; early development; epigenetics; life history; loci; nestlings; nests; phenotype; siblings; wild birds
Abstract:
... Both natural and experimentally manipulated brood size can influence the competition dynamics among siblings in a nest and alter the environment during early development in birds. Brood size affects a variety of life-history and fitness-related traits, but relatively little is known about the mechanisms that might mediate these effects. There is accumulating evidence that early-life environments c ...
DOI:
10.1642/AUK-18-61.1

4. Comparison of DNA methylation in developing seeds of Ricinus communis L. using MSAP analysis

Author:
Fenglan Huang; Mu Peng; Xiaofeng Chen; Guorui Li; Jianjun Di; Yong Zhao; Tongtong Jiang; Ruihui Chang; Lifeng Yang; Yongshen Chen
Source:
Biotechnology, biotechnological equipment 2018 v.32 no.4 pp. 858-864
ISSN:
1314-3530
Subject:
DNA methylation; Ricinus communis; adenosinetriphosphatase; biotechnology; demethylation; endosperm; epigenetics; equipment; gene expression; gene expression regulation; methyltransferases; seed maturation
Abstract:
... DNA methylation plays an important role in endosperm development and is involved in the epigenetic regulation of gene expression. However, the epigenetic regulation of castor seed development has not yet been reported. In this study, methylation-sensitive amplification polymorphism (MSAP) analysis was used to investigate the methylation level in castor. In 20-day-old castor seeds, 41.17% of the fr ...
DOI:
10.1080/13102818.2018.1470034

5. Effects of ethephon on DNA methylation and gene expressions associated with shortened internodes in maize

Author:
Daxuan Yao; Xiuai Huo; Tinashe Zenda; Songtao Liu; Yunting Liu; Liang Dai; Huijun Duan
Source:
Biotechnology, biotechnological equipment 2018 v.32 no.1 pp. 30-40
ISSN:
1314-3530
Subject:
DNA methylation; amplified fragment length polymorphism; apoptosis; biotechnology; corn; demethylation; energy; equipment; ethephon; gene expression regulation; leaves; signal transduction; start codon
Abstract:
... In this study, the molecular mechanism underlying ethephon-induced shortened internodes in maize was investigated using Zhengdan958 maize variety. The ethephon treatment was performed by spraying 225 mL/ha Ethephon 40% SL onto the foliage at the eight-expanded-leaves stage. The differentially expressed genes in the young internodes under ethephon treatment were identified through methylation-sensi ...
DOI:
10.1080/13102818.2017.1386591

6. Endometriosis Malignant Transformation: Epigenetics as a Probable Mechanism in Ovarian Tumorigenesis

Author:
Jiaxing He; Weiqin Chang; Chunyang Feng; Manhua Cui; Tianmin Xu
Source:
International Journal of Genomics 2018 v.2018 pp. -
ISSN:
2314-4378
Subject:
DNA methylation; animal ovaries; carcinogenesis; demethylation; endometrium; epigenetics; histones; microRNA; ovarian neoplasms; pain; risk factors; women
Abstract:
... Endometriosis, defined as the presence of ectopic endometrial glands and stroma outside the uterine cavity, is a chronic, hormone-dependent gynecologic disease affecting millions of women across the world, with symptoms including chronic pelvic pain, dysmenorrhea, dyspareunia, dysuria, and subfertility. In addition, there is well-established evidence that, although endometriosis is considered beni ...
DOI:
10.1155/2018/1465348
PubMed:
29780815
PubMed Central:
PMC5892233

7. Hepatic metabolite profiling of polychlorinated biphenyl (PCB)-resistant and sensitive populations of Atlantic killifish (Fundulus heteroclitus)

Author:
Lilah Glazer; Melissa C. Kido Soule; Krista Longnecker; Elizabeth B. Kujawinski; Neelakanteswar Aluru
Source:
Aquatic toxicology 2018 v.205 pp. 114-122
ISSN:
0166-445X
Subject:
DNA; DNA methylation; Fundulus heteroclitus; adults; amino acid metabolism; biosynthesis; coasts; demethylation; estuaries; fish; gene expression; genes; habitats; liver; metabolites; metabolomics; methyltransferases; nucleotides; polychlorinated biphenyls; rivers; sediments; streams; tissues; toxicity; Massachusetts
Abstract:
... Atlantic killifish inhabiting polluted sites along the east coast of the U.S. have evolved resistance to toxic effects of contaminants. One such contaminated site is the Acushnet River estuary, near New Bedford Harbor (NBH), Massachusetts, which is characterized by very high PCB concentrations in the sediments and in the tissues of resident killifish. Though killifish at this site appear to be thr ...
DOI:
10.1016/j.aquatox.2018.10.007
PubMed:
30368057
PubMed Central:
PMC6246827

8. Insights into the Biochemistry, Evolution, and Biotechnological Applications of the Ten-Eleven Translocation (TET) Enzymes

Author:
Mackenzie J. Parker; Peter R. Weigele; Lana Saleh
Source:
Biochemistry 2018 v.58 no.6 pp. 450-467
ISSN:
1520-4995
Subject:
DNA; DNA methylation; carbon; cytosine; demethylation; enzymes; epigenetics; evolution; gene expression regulation; human diseases; mammals; neoplasms; oxidation; tissues
Abstract:
... A tight link exists between patterns of DNA methylation at carbon 5 of cytosine and differential gene expression in mammalian tissues. Indeed, aberrant DNA methylation results in various human diseases, including neurologic and immune disorders, and contributes to the initiation and progression of various cancers. Proper DNA methylation depends on the fidelity and control of the underlying mechani ...
DOI:
10.1021/acs.biochem.8b01185

9. New Insights into the Methylation Status of Virulent Diuraphis noxia (Hemiptera: Aphididae) Biotypes

Author:
Kelly Breeds; N Francois V Burger; Anna-Maria Botha
Source:
Journal of economic entomology 2018 v.111 no.3 pp. 1395-1403
ISSN:
1938-291X
Subject:
DNA methylation; Diuraphis noxia; Triticum aestivum; biotypes; demethylation; epigenetics; fluorescence; genetic variation; genome; reproduction; virulence
Abstract:
... Epigenetic modifications provide a means for aphid biotype development that a lack of genetic variation, owing to an anholocyclic reproduction lifecycle, fails to do. Here we present data on the DNA methylation status in four South African Russian wheat aphids (RWA), Diuraphis noxia (Kurdjomov) (Hemiptera: Aphididae) biotypes expressing different levels of virulence against its host, Triticum aest ...
DOI:
10.1093/jee/toy039

10. S-adenosylmethionine reduces the inhibitory effect of Aβ on BDNF expression through decreasing methylation level of BDNF exon Ⅳ in rats

Author:
Dandan Cao; Jing Cui; Chenjia Guo; Guowen Min; Min Liu; Liang Li
Source:
Biochemical and biophysical research communications 2018 v.495 no.4 pp. 2609-2615
ISSN:
0006-291X
Subject:
DNA methylation; DNA methyltransferase; S-adenosylmethionine; demethylation; epigenetics; exons; messenger RNA; rats; research; transcription (genetics)
Abstract:
... The structure of brain-derived neurotrophic factor (BDNF) gene is complex, which is composed of eight non-coding exons and one coding exon, each of them has its own unique promoter. Multiple BDNF transcripts have distinct functional properties and epigenetic modulation of BDNF gene transcription is implicated in the neurological disorders. In the present study, rat models with amyloid-β (Aβ) intra ...
DOI:
10.1016/j.bbrc.2017.12.166

11. Temperature and photoperiod changes affect cucumber sex expression by different epigenetic regulations

Author:
Yun-Song Lai; Di Shen; Wei Zhang; Xiaohui Zhang; Yang Qiu; Haiping Wang; Xinxin Dou; Sigeng Li; Yuanqi Wu; Jiangping Song; Guanyu Ji; Xixiang Li
Source:
BMC plant biology 2018 v.18 no.1 pp. 268
ISSN:
1471-2229
Subject:
Cucumis sativus; DNA; DNA methylation; autumn; chromosomes; cucumbers; demethylation; epigenetics; female flowers; flowering; gene expression regulation; genes; germplasm conservation; photoperiod; seasonal variation; sex reversal; spring; temperature; transcriptome
Abstract:
... BACKGROUND: Cucumbers (Cucumis sativus) are known for their plasticity in sex expression. DNA methylation status determines gene activity but is susceptible to environmental condition changes. Thus, DNA methylation-based epigenetic regulation may at least partially account for the instability of cucumber sex expression. Do temperature and photoperiod that are the two most important environmental f ...
DOI:
10.1186/s12870-018-1490-3
PubMed:
30400867
PubMed Central:
PMC6220452

12. Transgene‐independent heredity of RdDM‐mediated transcriptional gene silencing of endogenous genes in rice

Author:
Yuhya Wakasa; Taiji Kawakatsu; Takeo Harada; Fumio Takaiwa
Source:
Plant biotechnology journal 2018 v.16 no.12 pp. 2007-2015
ISSN:
1467-7644
Subject:
DNA methylation; Oryza sativa; RNA; biotechnology; calnexin; demethylation; endoplasmic reticulum; endosperm; gene expression; glutelins; inheritance (genetics); multigene family; progeny; promoter regions; protein disulfide-isomerase; rice; transcription (genetics)
Abstract:
... To induce transcriptional gene silencing (TGS) of endogenous genes of rice (Oryza sativa L.), we expressed double‐strand RNA of each promoter region and thus induced RNA‐directed DNA methylation (RdDM). We targeted constitutively expressed genes encoding calnexin (CNX), protein disulphide isomerase (PDIL1‐1) and luminal binding protein (BiP1); an endoplasmic reticulum stress‐inducible gene (OsbZIP ...
DOI:
10.1111/pbi.12934
PubMed:
29704881
PubMed Central:
PMC6230945

13. The influence of Al3+ on DNA methylation and sequence changes in the triticale (× Triticosecale Wittmack) genome

Author:
Agnieszka Niedziela
Source:
Journal of applied genetics 2018 v.59 no.4 pp. 405-417
ISSN:
1234-1983
Subject:
DNA; DNA methylation; Triticosecale; abiotic stress; aluminum; crops; demethylation; drought; epigenetics; genes; heavy metals; leaves; mutation; phenotype; reversed-phase high performance liquid chromatography; roots; salinity; triticale
Abstract:
... Abiotic stressors such as drought, salinity, and exposure to heavy metals can induce epigenetic changes in plants. In this study, liquid chromatography (RP-HPLC), methylation amplified fragment length polymorphisms (metAFLP), and methylation-sensitive amplification polymorphisms (MSAP) analysis was used to investigate the effects of aluminum (Al) stress on DNA methylation levels in the crop specie ...
DOI:
10.1007/s13353-018-0459-0