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You searched for: Author "Rode, Kristina" Remove constraint Author: "Rode, Kristina" Publication Year 2018 Remove constraint Publication Year: 2018 Subject Sertoli cells Remove constraint Subject: Sertoli cells
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1. Loss of connexin 43 in Sertoli cells provokes postnatal spermatogonial arrest, reduced germ cell numbers and impaired spermatogenesis

Author:
Rode, Kristina,   et al.   ; Weider, Karola; Damm, Oliver Siegfried; Wistuba, Joachim; Langeheine, Marion; Brehm, Ralph;     Show all 6 Authors
Source:
Reproductive Biology 2018 v.18 no.4 pp. 456-466
ISSN:
1642-431X
Subject:
Sertoli cells; adulthood; adults; apoptosis; connexins; gap junctions; genotype; immunohistochemistry; males; mice; postnatal development; puberty; spermatocytes; spermatogenesis; spermatogonia
Abstract:
... For the reason that adult Sertoli cell specific connexin 43 knockout (SCCx43KO) mice show arrested spermatogenesis at spermatogonial level or Sertoli cell only tubules and significantly reduced germ cell (GC) numbers, the aims of the present study were (1) to characterize the remaining GC population and (2) to elucidate possible mechanisms of their fading. Apoptosis was analyzed in both, KO and wi ...
DOI:
10.1016/j.repbio.2018.08.001