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You searched for: Publication year rev 7982-2018 Remove constraint Publication year rev: 7982-2018 Subject term adipocytes Remove constraint Subject term: adipocytes Subject term bisphenol A Remove constraint Subject term: bisphenol A
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1. Bisphenol A: What lies beneath its induced diabetes and the epigenetic modulation?

Author:
Soheila Rahmani; Nazila Pour Khalili; Fazlullah Khan; Shokoufeh Hassani; Elmira Ghafour-Boroujerdi; Mohammad Abdollahi
Source:
Life sciences 2018 v.214 pp. 136-144
ISSN:
0024-3205
Subject:
DNA methylation; adipocytes; animals; bisphenol A; demethylation; endocrine-disrupting chemicals; epigenetics; estrogenic properties; fatty liver; genes; glucose; histones; homeostasis; insulin; islets of Langerhans; lipids; liver; microRNA; noninsulin-dependent diabetes mellitus; obesity; pollution; skeletal muscle; toxicity
Abstract:
... Nowadays, endocrine disrupting chemical pollution has become one of the major concerns due to the potential role of these chemicals in provoking endocrine disorders especially type 2 diabetes. As a widespread endocrine disrupting chemical, Bisphenol A, with modest estrogenic activity can exert its detrimental effects in the different organs involved in type 2 diabetes such as pancreas, liver, adip ...
DOI:
10.1016/j.lfs.2018.10.044

2. Sulforaphane attenuates bisphenol A-induced 3T3-L1 adipocyte differentiation through cell cycle arrest

Author:
Jin-Ha Lee; Bong-Yeon Cho; Seung-Hyun Choi; Tae-Dong Jung; Sun-Il Choi; Jeong-Ho Lim; Ok-Hwan Lee
Source:
Journal of functional foods 2018 v.44 pp. 17-23
ISSN:
1756-4646
Subject:
adipocytes; bisphenol A; cell cycle checkpoints; cyclins; diabetes; interphase; lipolysis; mitosis; obesity; phosphorylation; pollutants; risk factors; sulforaphane
Abstract:
... Bisphenol A (BPA) may be a critical risk factor for metabolic disorders including obesity and diabetes. Sulforaphane is known to inhibit adipocyte differentiation and induce adipocyte lipolysis. This study sought to investigate the possible effects of sulforaphane on BPA-induced adipocyte differentiation in 3T3-L1 cells. During the preadipocytes differentiation process, sulforaphane suppressed the ...
DOI:
10.1016/j.jff.2018.02.021