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- Sun, Baoshan, et al. Show all 7 Authors
- Journal of food science 2018 v.83 no.10 pp. 2622-2628
- antioxidants; cytotoxicity; drugs; foods; grape seeds; healthy diet; neurodegenerative diseases; neuroprotective effect; oxidative stress; polymerization; procyanidins; structure-activity relationships
- ... To establish a structure–activity relationship for procyanidins, we verified the cyto‐protective effect of 13 grape seed procyanidins, ranging from monomers to trimers against H₂O₂‐induced oxidative stress in PC‐12 neuroblastoma cells. Our study demonstrated some procyanidins were able to significantly protect PC‐12 cells from the H₂O₂‐induced cytotoxicity suggesting they possess neuroprotective e ...