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- Atashi, Amir; Islami, Maryam; Mortazavi, Yousef; Soleimani, Masoud
- Molecular biotechnology 2018 v.60 no.7 pp. 455-467
- umbilical cord, etc ; CXCR4 receptor; alpha chemokines; blood; bone marrow; cadherins; cell viability; fibronectins; flow cytometry; hematopoietic stem cells; lymphocyte function-associated antigen-1; quantitative polymerase chain reaction; scanning electron microscopy; transferases; Show all 14 Subjects
- ... Umbilical cord blood (UCB)-derived hematopoietic stem cells (HSCs) are considered because of their self-renewing, differentiating, proliferating, and readily available properties. Moreover, HSCsʼ homing to the hematopoietic microenvironment is an important step in their transplantation process. But low content of progenitor cells in one unit of UCB and defect in the bone marrow (BM) homing limit t ...
- Marinowic, Daniel Rodrigo; Zanirati, Gabriele; Azevedo, Pamella Nunes; De Souza, Eduardo Vieira; Bruzzo, Fernanda; Silva, Samara Pedroso da; Heuser, Eliete Biasotto; Machado, Denise Cantarelli; Da Costa, Jaderson Costa
- Cellular reprogramming 2018 v.20 no.5 pp. 320-327
- umbilical cord, etc ; adult stem cells; blood; bone marrow; cell cycle; cell viability; coculture; fibroblasts; gene expression; gene expression regulation; genes; humans; messenger RNA; quantitative polymerase chain reaction; reverse transcriptase polymerase chain reaction; therapeutics; toxicity testing; Show all 17 Subjects
- ... The human umbilical cord blood (HUCB) is an excellent source of adult stem cells, having the benefit of being younger than the bone marrow stem cells. The role of stem cells in the lesion repair mechanism is still being studied. We evaluated the capability of HUCB to interfere into the fibroblast dedifferentiation plasticity through cocultivation. Direct and indirect cocultures were maintained for ...