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- Klosowski, Daniel W.; Hethcox, J. Caleb; Paull, Daniel H.; Fang, Chao; Donald, James R.; Shugrue, Christopher R.; Pansick, Andrew D.; Martin, Stephen F.
- Journal of organic chemistry 2018 v.83 no.11 pp. 5954-5968
- regioselectivity, etc ; carboxylic acids; catalysts; chemical structure; diastereoselectivity; enantioselective synthesis; enantioselectivity; epoxidation reactions; lactones; organic chemistry; protocols; Show all 11 Subjects
- ... A general protocol is described for inducing enantioselective halolactonizations of unsaturated carboxylic acids using novel bifunctional organic catalysts derived from a chiral binaphthalene scaffold. Bromo- and iodolactonization reactions of diversely substituted, unsaturated carboxylic acids proceed with high degrees of enantioselectivity, regioselectivity, and diastereoselectivity. Notably, th ...
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