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1. Cloning and characterization of lipoprotein lipase (LPL) and the effects of dietary lipid levels on the expression of LPL in the redlip mullet (Liza haematocheila)

Author:
Wang, A.,   et al.   ; Yang, W.; Liu, F.; Wang, Z.; Cang, P.; Yin, X.; Yu, Y.; Qiao, G.; Ni, J.;     Show all 9 Authors
Source:
Aquaculture nutrition 2018 v.24 no.2 pp. 832-841
ISSN:
1353-5773
Subject:
Liza; abdominal fat; amino acids; aquaculture; breeding programs; crude fat; dietary fat; gene expression; genes; genetic improvement; high fat diet; lipids; lipoprotein lipase; messenger RNA; metabolism; quantitative polymerase chain reaction; sequence analysis; tissues
Abstract:
... The genetic improvement of redlip mullet Liza haematocheila through breeding programmes is of interest for this important aquaculture species. Lipoprotein lipase (LPL) is a key enzyme in lipid deposition and metabolism. The purpose of this study was to investigate the nutritional regulation of LPL in redlip mullet. We cloned and identified the LPL gene, determined LPL gene expression in various ti ...
DOI:
10.1111/anu.12612

2. Curcumin attenuates heat-stress-induced oxidant damage by simultaneous activation of GSH-related antioxidant enzymes and Nrf2-mediated phase II detoxifying enzyme systems in broiler chickens

Author:
Wang, A A,   et al.   ; Zhang, J F; Bai, K W; Su, W P; Zhang, L L; Huang, K H; Wang, T;     Show all 7 Authors
Source:
Poultry science 2018 v.97 no.4 pp. 1209-1219
ISSN:
1525-3171
Subject:
antioxidant activity; antioxidant enzymes; blood serum; body temperature; broiler chickens; copper; corticosterone; curcumin; enzyme activity; feed conversion; feed supplements; feet; genes; glutathione; glutathione peroxidase; head; heat stress; heat treatment; liver; males; malondialdehyde; metabolic detoxification; mitochondria; muscles; oxidants; rearing; signal transduction
Abstract:
... The object of this study was to investigate the effect of curcumin on modulating the glutathione (GSH)-related antioxidant enzymes and antioxidant responses via NF-E2-related factor 2 (Nrf2) signaling pathway in heat-stressed broiler chickens. A total of 400 one-day-old male Arbor Acres broiler chicks was reared in an environmentally controlled room. At 21 d, broiler chicks were divided into 5 tre ...
DOI:
10.3382/ps/pex408

3. A Muscle-Specific Enhancer RNA Mediates Cohesin Recruitment and Regulates Transcription In trans

Author:
Wang, A. Hongjun,   et al.   ; Tsai, Pei-Fang; Dell’Orso, Stefania; Rodriguez, Joseph; Vivanco, Karinna O.; Ko, Kyung-Dae; Jiang, Kan; Juan, Aster H.; Sarshad, Aishe A.; Vian, Laura; Tran, Michelle; Wangsa, Darawalee; Perovanovic, Jelena; Anastasakis, Dimitrios; Ralston, Evelyn; Ried, Thomas; Sun, Hong-Wei; Hafner, Markus; Larson, Daniel R.; Sartorelli, Vittorio;     Show all 20 Authors
Source:
Molecular cell 2018 v.71 no.1 pp. 129-141.e8
ISSN:
1097-2765
Subject:
RNA; cell differentiation; chromatin; gene expression; genes; loci; myogenin; transcription (genetics)
Abstract:
... The enhancer regions of the myogenic master regulator MyoD give rise to at least two enhancer RNAs. Core enhancer eRNA (CᴱeRNA) regulates transcription of the adjacent MyoD gene, whereas ᴰᴿᴿeRNA affects expression of Myogenin in trans. We found that ᴰᴿᴿeRNA is recruited at the Myogenin locus, where it colocalizes with Myogenin nascent transcripts. ᴰᴿᴿeRNA associates with the cohesin complex, and t ...
DOI:
10.1016/j.molcel.2018.06.008
PubMed:
29979962
PubMed Central:
PMC6082425