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- Gao, Wenchao, et al. Show all 5 Authors
- Organic letters 2018 v.20 no.18 pp. 5914-5917
- catalysts; chemical structure; enantioselectivity; hydrogenation; organic compounds; protocols
- ... The nickel/(S)-Binapine complex was found to be an efficient catalyst for asymmetric hydrogenation of β-acetylamino vinylsulfones to afford chiral β-Amido sulfones with excellent yields and enantioselectivities (up to 95% yields and >99% ee). This protocol has good compatibility with a series of substituted (Z)-β-acetylamino vinylsulfones or Z/E isomeric mixtures. A gram-scale reaction has also be ...