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- Paumann-Page, Martina, et al. Show all 5 Authors
- Archives of biochemistry and biophysics 2018 v.646 pp. 120-127
- acetaminophen; bromides; catalase; collagen; crosslinking; enzyme activity; enzyme inhibitors; epithelial cells; extracellular matrix; hydrazides; hydrogen peroxide; hydroxylysine; mass spectrometry; methionine; myeloperoxidase; oxidation; peroxidase; thiocyanates
- ... Peroxidasin is a heme peroxidase that catalyses the oxidation of bromide by hydrogen peroxide to form an essential sulfilimine cross-link between methionine and hydroxylysine residues in collagen IV. We investigated cross-linking by peroxidasin embedded in extracellular matrix isolated from cultured epithelial cells and its sensitivity to alternative substrates and peroxidase inhibitors. Peroxidas ...