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- Vogel, Christine, et al. Show all 4 Authors
- Journal of proteome research 2018 v.18 no.1 pp. 309-318
- hydrogen peroxide; mass spectrometry; oxidative stress; polyribosomes; protein transport; proteome; stress response; ubiquitin; ubiquitination; yeasts
- ... During oxidative stress, K63-linked polyubiquitin chains modify a variety of proteins including ribosomes. Knowledge of the precise sites of K63 ubiquitin is key to understand its function during the response to stress. To identify the sites of K63 ubiquitin, we developed a new mass spectrometry based method that quantified >1100 K63 ubiquitination sites in yeast that responded to oxidative stress ...