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- Author:
- Monk, Jennifer M.; Wu, Wenqing; McGillis, Laurel H.; Wellings, Hannah R.; Hutchinson, Amber L.; Liddle, Danyelle M.; Graf, Daniela; Robinson, Lindsay E.; Power, Krista A.
- Source:
- Applied physiology, nutrition and metabolism 2018 v.43 no.9 pp. 893-901
- ISSN:
- 1715-5320
- Subject:
- biomarkers; blood serum; chickpeas; colitis; colon; dextran; diet; drinking water; epithelium; flour; gene expression; histology; immunoglobulin A; inflammation; interleukin-10; males; mice; phenolic compounds; protein synthesis; signs and symptoms (animals and humans); sodium; transcription factor NF-kappa B; tumor necrosis factor-alpha
- Abstract:
- ... The potential for a chickpea-supplemented diet (rich in fermentable nondigestible carbohydrates and phenolic compounds) to modify the colonic microenvironment and attenuate the severity of acute colonic inflammation was investigated. C57Bl/6 male mice were fed a control basal diet or basal diet supplemented with 20% cooked chickpea flour for 3 weeks prior to acute colitis onset induced by 7-day ex ...
- DOI:
- 10.1139/apnm-2017-0689
-
http://dx.doi.org/10.1139/apnm-2017-0689
- Author:
- Nfon, C.; Lusansky, D.; Goolia, M.; Yang, M.; Hole, K.; McIntyre, L.
- Source:
- Canadian journal of veterinary research 2018 v.82 no.4 pp. 316-321
- ISSN:
- 0830-9000
- Subject:
- Jersey; antibodies; antigens; blood serum; diagnostic sensitivity; enzyme-linked immunosorbent assay; foot-and-mouth disease; glycoproteins; hosts; laboratory experimentation; mice; signs and symptoms (animals and humans); vesicular stomatitis; veterinary medicine; viruses
- Abstract:
- ... Foot-and-mouth disease (FMD) and vesicular stomatitis (VS) cause such similar clinical signs and lesions that laboratory tests are required to distinguish between infections caused by each virus. Using mouse anti-foot-and-mouth disease virus (FMDV) 3B monoclonal or polyclonal anti-vesicular stomatitis virus-New Jersey (VSV-NJ) antibodies and recombinant FMDV 3ABC or VSV-NJ glycoprotein (G) antigen ...
-
- Author:
- Micaele, Quintana de Moura; Marcia, Raquel Pegoraro de Macedo; da Silva Terto, Wesley Douglas; da Costa Avila, Luciana Farias; Fabio, Pereira Leivas Leite; Carlos, Jaime Scaini; Natália, Berne Pinto; Gabriela, de Almeida Capella; Adriane, Leites Strothmann; Marcos, Marreiro Villela; Maria, Elisabeth Aires Berne
- Source:
- Acta tropica 2018
- ISSN:
- 0001-706X
- Subject:
- DNA; Toxocara canis; acute course; blood sampling; blood serum; brain; digestion; eggs; enzyme-linked immunosorbent assay; etiological agents; helminths; infectious diseases; internal transcribed spacers; larvae; liver; lungs; mice; polymerase chain reaction; signs and symptoms (animals and humans); tissues; toxocariasis
- Abstract:
- ... The main etiological agent of toxocariasis is the helminth Toxocara canis. Several difficulties are found in the diagnosis of this disease, because of nonspecific clinical signs and possible cross-reactions that may occur in the available test, the indirect ELISA. Therefore, molecular diagnosis has been indicated as an alternative to conventional diagnosis. The purpose of this study was to evaluat ...
- DOI:
- 10.1016/j.actatropica.2018.07.017
-
https://dx.doi.org/10.1016/j.actatropica.2018.07.017
- Author:
- Ohta, H.; Kojima, K.; Yokoyama, N.; Sasaki, N.; Kagawa, Y.; Hanazono, K.; Ishizuka, T.; Morishita, K.; Nakamura, K.; Takaqi, S.; Takiguchi, M.
- Source:
- Canadian journal of veterinary research 2018 v.82 no.4 pp. 278-286
- ISSN:
- 0830-9000
- Subject:
- Beagle; biopsy; blood serum; body weight; dogs; gene expression; histology; histopathology; immunosuppression; laparoscopy; liver; messenger RNA; pancreas; pancreatitis; polymerase chain reaction; prednisolone; signs and symptoms (animals and humans); triacylglycerol lipase; ultrasonography; veterinary medicine
- Abstract:
- ... The objective of this study was to examine the effects of immunosuppressive prednisolone therapy on pancreatic tissue and the concentration of serum canine pancreatic lipase immunoreactivity (cPLI) in healthy dogs. Six healthy beagle dogs were subcutaneously administered an immunosuppressive dose of prednisolone [4 mg/kg body weight (BW)] once daily for either 2 or 3 weeks. Serum cPLI concentratio ...
-
- Author:
- Pasolini, Maria P.; Pagano, Teresa B.; Costagliola, Alessandro; Biase, Davide De; Lamagna, Barbara; Auletta, Luigi; Fatone, Gerardo; Greco, Michele; Coluccia, Pierpaolo; Veneziano, Veneziano; Pirozzi, Claudio; Raso, Giuseppina Mattace; Santoro, Pasquale; Manna, Giuseppe; Papparella, Serenella; Paciello, Orlando
- ISSN:
- 1544-2217
- Subject:
- Babesia caballi; T-lymphocytes; Theileria equi; animal pathology; antigens; autoantibodies; blood serum; equine piroplasmosis; fluorescent antibody technique; gene expression; histopathology; horses; immunoglobulin A; immunoglobulin G; immunoglobulin M; immunohistochemistry; interferon-gamma; interleukin-12; major histocompatibility complex; muscle fibers; muscles; muscular atrophy; muscular diseases; pathogenesis; reverse transcriptase polymerase chain reaction; signs and symptoms (animals and humans); skeletal muscle; staining; tumor necrosis factor-alpha
- Abstract:
- ... Horses affected by chronic piroplasmosis may develop poor performance and muscle atrophy. Here we investigate the pathological and immunopathological aspects of myopathy occurring in chronic equine piroplasmosis. The study included 16 horses serologically positive for equine piroplasms presenting with clinical signs and supporting serum biochemical evidence of a myopathy. Skeletal muscle was evalu ...
- DOI:
- 10.1177/0300985817716262
-
http://dx.doi.org/10.1177/0300985817716262
- Author:
- Lamb, Christopher R; Cortellini, Stefano; Halfacree, Zoe
- ISSN:
- 1532-2750
- Subject:
- blood serum; cats; creatinine; cross-sectional studies; death; hospitals; image analysis; kidneys; pelvis; radiography; regression analysis; risk; signs and symptoms (animals and humans); ultrasonography; ureter; urinary calculi
- Abstract:
- ... The objective was to identify clinical or ultrasonographic results associated with ureteral obstruction or outcome in cats with azotaemia. This was a retrospective cross-sectional study of cats with azotaemia (serum creatinine >180 μmol/l) that had ultrasonography of the urinary tract, ultrasound images available for review and received treatment for azotaemia. Cats with pre-renal azotaemia or ure ...
- DOI:
- 10.1177/1098612X17694253
-
http://dx.doi.org/10.1177/1098612X17694253
- Author:
- Kristensen, Charlotte S.; Kvisgaard, L.K.; Pawlowski, M.; Holmgaard Carlsen, S.; Hjulsager, C.K.; Heegaard, P.M.H.; Bøtner, A.; Stadejek, T.; Haugegaard, S.; Larsen, L.E.
- Source:
- Vaccine 2018 v.36 no.2 pp. 227-236
- ISSN:
- 0264-410X
- Subject:
- Porcine reproductive and respiratory syndrome virus; blood serum; experimental design; herds; lungs; necropsy; nose; porcine reproductive and respiratory syndrome; protective effect; signs and symptoms (animals and humans); swine; vaccination; vaccines; viral load; viremia; viruses
- Abstract:
- ... The objective of the study was to compare responses of pigs vaccinated with a PRRS MLV vaccine against PRRSV-1 or PRRSV-2 with the responses of pigs vaccinated simultaneously with both vaccines. Furthermore, the efficacy of the two PRRSV MLV vaccination strategies was assessed following challenge. The experimental design included four groups of 4-weeks old SPF-pigs. On day 0 (DPV0), groups 1–3 (N= ...
- DOI:
- 10.1016/j.vaccine.2017.11.059
-
http://dx.doi.org/10.1016/j.vaccine.2017.11.059
- Author:
- Sánchez-Cordón, Pedro J.; Jabbar, Tamara; Berrezaie, Margot; Chapman, Dave; Reis, Ana; Sastre, Patricia; Rueda, Paloma; Goatley, Lynnette; Dixon, Linda K.
- Source:
- Vaccine 2018 v.36 no.5 pp. 707-715
- ISSN:
- 0264-410X
- Subject:
- African swine fever virus; antibodies; blood serum; death; enzyme-linked immunosorbent assay; genes; immunization; immunoglobulin G; immunoglobulin M; interleukin-10; live vaccines; mutants; signs and symptoms (animals and humans); swine; temperature; viremia; virulence; virulent strains; viruses; Benin
- Abstract:
- ... A live attenuated African swine fever virus (ASFV) vaccine candidate, produced by deletion of several genes belonging to multi-gene families MGF360 and 505 from virulent Benin 97/1 strain (BeninΔMGF), induces protection in pigs against parental virulent strain. In order to better define the safety and efficacy of this attenuated vaccine candidate and to understand protective mechanisms, we extende ...
- DOI:
- 10.1016/j.vaccine.2017.12.030
-
http://dx.doi.org/10.1016/j.vaccine.2017.12.030
- Author:
- Faria, Joice L. M.; Couto, Caroline do; Wierzynski, Sheron L.; Bottari, Nathieli B.; Baldissera, Matheus D.; Pereira, Wanderson A. B.; Da Silva, Aleksandro S.
- Source:
- The Journal of parasitology 2018 v.104 no.1 pp. 86-88
- ISSN:
- 0022-3395
- Subject:
- Protozoa; Toxoplasma gondii; antibodies; blood serum; cats; fluorescent antibody technique; free radicals; humans; inflammation; nitric oxide; reactive oxygen species; seroprevalence; signs and symptoms (animals and humans); toxoplasmosis; tumor necrosis factor-alpha; Brazil
- Abstract:
- ... Toxoplasma gondii is a cosmopolitan protozoan that causes disease in several species, including humans. In cats, these infections are usually asymptomatic, but in other species they can lead to high levels of inflammatory and cell damage markers, causing cellular damage. Therefore, the aim of this study was to measure levels of tumor necrosis factor (TNF-α), reactive oxygen species (ROS), and nitr ...
- DOI:
- 10.1645/17-85
-
http://dx.doi.org/10.1645/17-85
- Author:
- Kedkovid, Roongtham; Woonwong, Yonlayong; Arunorat, Jirapat; Sirisereewan, Chaitawat; Sangpratum, Nattaphong; Lumyai, Mongkol; Kesdangsakonwut, Sawang; Teankum, Komkrich; Jittimanee, Suphattra; Thanawongnuwech, Roongroje
- Source:
- Veterinary microbiology 2018 v.215 pp. 71-76
- ISSN:
- 0378-1135
- Subject:
- Porcine circovirus; Porcine circovirus-3; blood serum; farms; feeder pigs; pathogenesis; polymerase chain reaction; respiratory tract diseases; sequence analysis; signs and symptoms (animals and humans); swine diseases; viruses; Thailand
- Abstract:
- ... Porcine circovirus type 3 (PCV3) is a newly emerging virus with unknown pathogenesis. The major objective of this study was to investigate the presence of PCV3 in pigs from a farm in Thailand suffering from porcine respiratory disease complex (PRDC). Initially, a Thai PCV3 strain (PCV3/Thailand/PB01/17) was identified from a pig originated from a farm with PRDC problem during grower period and who ...
- DOI:
- 10.1016/j.vetmic.2018.01.004
-
https://dx.doi.org/10.1016/j.vetmic.2018.01.004
- Author:
- Zhang, Guanshi; Dervishi, Elda; Ametaj, Burim N.
- Source:
- Research in veterinary science 2018 v.116 pp. 72-82
- ISSN:
- 0034-5288
- Subject:
- 3-hydroxybutyric acid; Holstein; amyloid; biomarkers; blood serum; carbohydrate metabolism; dairy cows; discriminant analysis; disease diagnosis; disease occurrence; free fatty acids; haptoglobins; health status; innate immunity; interleukin-1; interleukin-6; lactic acid; least squares; lipid metabolism; longitudinal studies; milk fat; milk fever; milk yield; parturition; principal component analysis; signs and symptoms (animals and humans); tumor necrosis factors
- Abstract:
- ... The objective of this study was to search for potential alterations in innate immunity reactants and carbohydrate and lipid metabolism in the blood of transition dairy cows before, during, and after clinical occurrence of milk fever (MF) and identify potential predictive biomarkers of disease. One hundred pregnant multiparous Holstein dairy cows were involved in the study starting from −8wks befor ...
- DOI:
- 10.1016/j.rvsc.2018.02.013
-
http://dx.doi.org/10.1016/j.rvsc.2018.02.013
- Author:
- Cervantes-Llanos, Majel; Lagumersindez-Denis, Nielsen; Marín-Prida, Javier; Pavón-Fuentes, Nancy; Falcon-Cama, Viviana; Piniella-Matamoros, Beatriz; Camacho-Rodríguez, Hanlet; Fernández-Massó, Julio Raúl; Valenzuela-Silva, Carmen; Raíces-Cruz, Ivette; Pentón-Arias, Eduardo; Teixeira, Mauro Martins; Pentón-Rol, Giselle
- Source:
- Life sciences 2018 v.194 pp. 130-138
- ISSN:
- 0024-3205
- Subject:
- blood serum; interferon-gamma; brain; interleukin-6; signs and symptoms (animals and humans); enzyme-linked immunosorbent assay; mice; sclerosis; animal models; encephalitis; Arthrospira platensis; patients; quality of life; transmission electron microscopy; oral administration; spinal cord; oxidative stress; rats
- Abstract:
- ... The only three oral treatments currently available for multiple sclerosis (MS) target the relapsing forms of the disease and concerns regarding efficacy, safety and tolerability limit their use. Identifying novel oral disease-modifying therapies for MS, targeting both its inflammatory and neurodegenerative components is still a major goal.The scope of this study was to provide evidence that the or ...
- DOI:
- 10.1016/j.lfs.2017.12.032
-
http://dx.doi.org/10.1016/j.lfs.2017.12.032
- Author:
- CAMOIN, MARGOT; KOCHER, ARTHUR; CHALERMWONG, PIANGJAI; YANGTARRA, SARAWUT; THONGTIP, NIKORN; JITTAPALAPONG, SATHAPORN; DESQUESNES, MARC
- Source:
- Parasitology 2018 v.145 no.3 pp. 371-377
- ISSN:
- 1469-8161
- Subject:
- Elephas maximus; Trypanosoma evansi; antibodies; blood serum; buffaloes; cattle; diminazene; disease reservoirs; drugs; endangered species; enzyme-linked immunosorbent assay; etiological agents; monitoring; screening; serological surveys; seroprevalence; signs and symptoms (animals and humans); surra; trypanocides; wildlife; Thailand
- Abstract:
- ... Trypanosoma evansi, the causative agent of surra, is widespread in domestic livestock and wildlife in South East Asia. Surra can affect cattle, buffaloes, horses and also Asian elephants (Elephas maximus). Despite the ‘threatened to extinction’ CITES status of elephant, surra's impact has not been thoroughly assessed yet in this species. This work offers to adapt an antibody enzyme-linked immunoso ...
- DOI:
- 10.1017/S0031182017001585
- PubMed:
- 28942737
-
http://dx.doi.org/10.1017/S0031182017001585
- Author:
- Zou, X.; Ji, J.; Wang, J.; Qu, H.; Shu, D. M.; Guo, F. Y.; Luo, C. L.
- Source:
- British poultry science 2018 v.59 no.2 pp. 166-172
- ISSN:
- 1466-1799
- Subject:
- blood serum; chickens; dose response; feces; histology; histopathology; ileum; inflammation; interleukin-10; interleukin-1beta; models; mucus; signs and symptoms (animals and humans); tumor necrosis factor-alpha; villi; weight loss
- Abstract:
- ... 1. The clinical severity, histological changes, indicators of gut leakiness and inflammatory cytokine profiles were studied in chickens with dextran sulphate sodium (DSS)-induced intestinal inflammation. 2. The experimental groups (1.25%, 1.5% and 2.5% DSS) showed clinical signs, such as loose stools and weight loss, which increased with additional treatment days and, as expected, the effects of D ...
- DOI:
- 10.1080/00071668.2017.1418498
-
http://dx.doi.org/10.1080/00071668.2017.1418498
- Author:
- Naik, Sadanand; Mahalle, Namita; Bhide, Vijayshri
- Source:
- The British journal of nutrition 2018 v.119 no.6 pp. 629-635
- ISSN:
- 1475-2662
- Subject:
- at-risk population; biomarkers; blood serum; disease diagnosis; females; folic acid; graphs; homocysteine; males; signs and symptoms (animals and humans); vegetarian diet; vitamin B12
- Abstract:
- ... The prevalence of a sub-clinical vitamin B₁₂ deficiency in the vegetarians is high. Total serum vitamin B₁₂ concentration alone does not reliably reflect vitamin B₁₂ status. Holotranscobalamin (holo-TC) II is a bioactive B₁₂ fraction promoting specific uptake of B₁₂ by cells and the circulating concentration reflects the intake of B₁₂, whereas total homocysteine (tHcy) indicates the metabolic abil ...
- DOI:
- 10.1017/S0007114518000090
- PubMed:
- 29446340
-
http://dx.doi.org/10.1017/S0007114518000090
- Author:
- Hajimohammadi, Ali; Badiei, Khalil; Kheibari, Parviz; Pourjafar, Meherdad; Chalmeh, Aliasghar
- Source:
- Journal of Veterinary Research 2018 v.62 no.1 pp. 79-85
- ISSN:
- 2450-8608
- Subject:
- Escherichia coli; blood serum; endotoxemia; haptoglobins; heart; intravenous injection; lactic acid; lipopolysaccharides; polymyxin B; respiratory rate; serotypes; sheep; signs and symptoms (animals and humans); temperature; tumor necrosis factor-alpha; veterinary medicine
- Abstract:
- ... The experiment evaluated the effects of intravenous administration of polymyxin B on experimental endotoxaemia in sheep. Twenty clinically healthy fat-tailed sheep were randomly divided into: a group treated with 6,000 U/kg of polymyxin B, a group at 12,000 U/kg, and positive and negative controls. Endotoxaemia was induced by intravenous administration of lipopolysaccharide (LPS) from E. coli sero ...
- DOI:
- 10.2478/jvetres-2018-0011
-
https://dx.doi.org/10.2478/jvetres-2018-0011
- Author:
- Benedicenti, L.; Gianotti, G.; Galban, E. M.
- Source:
- Canadian journal of veterinary research 2018 v.82 no.2 pp. 97-101
- ISSN:
- 0830-9000
- Subject:
- blood serum; brain; cerebrospinal fluid; dogs; lactic acid; magnetic resonance imaging; prospective studies; signs and symptoms (animals and humans); veterinary medicine
- Abstract:
- ... The objectives of this study were to investigate the relationship between cerebrospinal fluid lactate and serum concentrations in dogs with clinical signs of central nervous system disease and to establish if cerebrospinal fluid lactate (CSF) concentrations are higher in dogs with structural intracranial disease (Group Pos-MRI) compared to dogs that have clinical signs of intracranial disease but ...
-
- Author:
- Kim, Hyun-Ji; Ko, Je-Won; Cha, Seung-Beom; Heo, Hyun-Suk; Seo, Jong-Hun; Cha, Mi-Jin; Bae, Jin-Sook; Lee, Hyun-Kul; Song, Si-Whan; Kim, Jong-Choon
- Source:
- Food and chemical toxicology 2018 v.114 pp. 41-51
- ISSN:
- 0278-6915
- Subject:
- Areca catechu; alanine transaminase; alkaline phosphatase; aspartate transaminase; bilirubin; blood chemistry; blood serum; body weight changes; diarrhea; estrous cycle; female reproductive system; females; food consumption; hematology; histopathology; ketone bodies; kidneys; liver; mortality; necrosis; oral administration; rats; signs and symptoms (animals and humans); specific gravity; spermatozoa; toxicity; urinalysis; urine
- Abstract:
- ... This study investigated the potential toxicity of the Areca catechu water extract after 13-week repeated oral administration at 0, 166.7, 500, and 1500 mg/kg/day in rats. During the study period, clinical signs, mortality, body weight, food consumption, water consumption, urinalysis, estrous cycle, sperm count and motility, ophthalmoscopy, hematology, serum biochemistry, gross pathology, organ wei ...
- DOI:
- 10.1016/j.fct.2018.02.015
-
http://dx.doi.org/10.1016/j.fct.2018.02.015
- Author:
- Cantos-Barreda, Ana; Escribano, Damián; Cerón, José J.; Tecles, Fernando; Bernal, Luis J.; Martínez-Subiela, Silvia
- Source:
- Veterinary parasitology 2018 v.254 pp. 135-141
- ISSN:
- 0304-4017
- Subject:
- Leishmania; allopurinol; antibodies; blood serum; chemical species; dogs; fluorometry; immunoglobulin A; immunoglobulin G; leishmaniasis; monitoring; saliva; signs and symptoms (animals and humans); therapeutics
- Abstract:
- ... The aim of this study was to evaluate the possible changes in the concentration of anti-Leishmania antibodies in saliva samples from dogs with clinical leishmaniosis after short-term treatment. Twenty dogs with clinical signs and laboratory abnormalities compatible with canine leishmaniosis (CanL) were diagnosed and treated with a standard antimonial plus allopurinol therapy. The concentration of ...
- DOI:
- 10.1016/j.vetpar.2018.03.014
-
http://dx.doi.org/10.1016/j.vetpar.2018.03.014
- Author:
- Schueler, R. O.; White, G.; Schueler, R. L.; Steiner, J. M.; Wassef, A.
- Source:
- Thejournal of small animal practice 2018 v.59 no.5 pp. 305-310
- ISSN:
- 0022-4510
- Subject:
- adrenal cortex hormones; blood serum; digestive system diseases; dogs; image analysis; immunoassays; intervertebral disks; neurological examination; nonsteroidal anti-inflammatory agents; signs and symptoms (animals and humans); triacylglycerol lipase
- Abstract:
- ... OBJECTIVE: To determine the differences in serum canine pancreatic lipase immunoreactivity between dogs with intervertebral disc herniation and healthy control dogs. MATERIALS AND METHODS: Eighty‐four client‐owned dogs with intervertebral disc herniation, diagnosed by neurologic examination and imaging, and 18 healthy control dogs. Samples of whole blood were collected within 90 minutes of admissi ...
- DOI:
- 10.1111/jsap.12818
-
https://dx.doi.org/10.1111/jsap.12818