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- Jain, Rishi, et al. Show all 5 Authors
- Biomacromolecules 2018 v.19 no.7 pp. 2401-2408
- depolymerization; eukaryotic cells; microtubules; neoplasms; neurodegenerative diseases; osmotic pressure; paclitaxel; physiology; polyethylene glycol; polymerization; proteins; therapeutics
- ... Microtubule dynamics play a critical role in the normal physiology of eukaryotic cells as well as a number of cancers and neurodegenerative disorders. The polymerization/depolymerization of microtubules is regulated by a variety of stabilizing and destabilizing factors, including microtubule-associated proteins and therapeutic agents (e.g., paclitaxel, nocodazole). Here we describe the ability of ...