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- Burger, Trevor; Mokoka, Tsholofelo; Fouché, Gerda; Steenkamp, Paul; Steenkamp, Vanessa; Cordier, Werner
- BMC complementary and alternative medicine 2018 v.18 no.1 pp. 137
- P-glycoproteins, etc ; Solanum aculeastrum; additive effect; alternative medicine; antineoplastic activity; cell death; cell lines; cytotoxicity; dose response; doxorubicin; fruits; inhibitory concentration 50; liquid-liquid extraction; maceration; mass spectrometry; neoplasms; nuclear magnetic resonance spectroscopy; solanine; solid phase extraction; thin layer chromatography; ultra-performance liquid chromatography; ultrasonics; Show all 22 Subjects
- ... BACKGROUND: Solanum aculeastrum fruits are used by some cancer sufferers as a form of alternative treatment. Scientific literature is scarce concerning its anticancer activity, and thus the aim of the study was to assess the in vitro anticancer and P-glycoprotein inhibitory potential of extracts of S. aculeastrum fruits. Furthermore, assessment of the combinational effect with doxorubicin was also ...
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