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651. Development of immunoassays for multi-residue detection of small molecule compounds

Author:
Cui, Xueyan; Jin, Maojun; Du, Pengfei; Chen, Ge; Zhang, Chan; Zhang, Yudan; Shao, Yong; Wang, Jing
Source:
Food and agricultural immunology 2018 v.29 no.1 pp. 638-652
ISSN:
1465-3443
Subject:
toxins,   etc   ; animals; heavy metals; human health; immunoassays; pesticides; plants (botany); soil; veterinary drugs;     Show all 9 Subjects
Abstract:
... The small molecule compounds like pesticide, veterinary drug, bio-toxin, and heavy metal are widely found in animals, plants, soil, etc. Excessive compounds residues will have a bad influence on human health and the environment. Thus, it is extremely urgent that can detect the small molecules simultaneously. At present, many researches of simultaneous detection for small molecules using the method ...
DOI:
10.1080/09540105.2018.1428284

652. 3,4-Diaminotoluene sensor development based on hydrothermally prepared MnCoxOy nanoparticles

Author:
Rahman, Mohammed M.; Alam, M.M.; Asiri, Abdullah M.; Islam, M.A.
Source:
Talanta 2018 v.176 pp. 17-25
ISSN:
0039-9140
Subject:
toxins,   etc   ; Fourier transform infrared spectroscopy; X-ray diffraction; X-ray photoelectron spectroscopy; ambient temperature; energy-dispersive X-ray analysis; glassy carbon electrode; health services; nanoparticles; scanning electron microscopy; ultraviolet-visible spectroscopy;     Show all 11 Subjects
Abstract:
... A facile hydrothermal process was used to prepare MnCoxOy nanoparticles (NPs) in alkaline medium (pH~10.5) at room temperature. The NPs were characterized by Fourier-transform infrared spectroscopy (FTIR), ultraviolet visible spectroscopy (UV/vis), field emission scanning electron microscopy (FESEM), X-ray photoelectron spectroscopy (XPS), energy-dispersive X-ray spectroscopy (EDS), and powder X-r ...
DOI:
10.1016/j.talanta.2017.07.093

653. Effect of T-2 toxin and antioxidants on angel wing incidence and severity in White Roman geese

Author:
Lin, Min-Jung; Chang, Shen-Chang; Tso, Ko-Hua; Lin, Wei-Chih; Chang, Che-Lun; Lee, Tzu-Tai
Source:
Journal of applied animal research 2018 v.46 no.1 pp. 340-348
ISSN:
0974-1844
Subject:
T-2 toxin,   etc   ; alkaline phosphatase; antioxidants; ascorbic acid; body weight changes; diet; goslings; hemoglobin;     Show all 8 Subjects
Abstract:
... This study investigates the effects of T-2 toxin and antioxidants on the incidence and severity of angel wing in White Roman geese. Twelve pens were used in this study, and half of them received dietary supplementation of T-2 toxin (10 ppm) and antioxidants (vitamin C 1000 ppm plus Se 0.3 ppm). Each pen contained birds from the normal wing line (NL), the selected angel wing line (AL), and a contro ...
DOI:
10.1080/09712119.2017.1301257

654. Exposure of engineered nanoparticles to Alexandrium tamarense (Dinophyceae): Healthy impacts of nanoparticles via toxin-producing dinoflagellate

Author:
Li, Manlu; Chen, Daoyi; Liu, Yang; Chuang, Chia Ying; Kong, Fanzhou; Harrison, Paul J.; Zhu, Xiaoshan; Jiang, Yuelu
Source:
The Science of the total environment 2018 v.610-611 pp. 356-366
ISSN:
0048-9697
Subject:
toxins,   etc   ; Alexandrium tamarense; algal blooms; aluminum oxide; aquatic organisms; coastal water; dose response; growth retardation; humans; nanoparticles; paralytic shellfish poisoning; photosynthesis; poisoning; reactive oxygen species; titanium dioxide; zinc oxide;     Show all 16 Subjects
Abstract:
... Human activities can enhance the frequency, intensity and occurrence of harmful algal blooms (HABs). Engineered nanoparticles (ENPs), contained in many materials, will inevitably enter coastal waters and thus cause unpredictable impacts on aquatic organisms. However, knowledge of the influence of ENPs on HAB species is still lacking. In this study, we examined the effects of titanium dioxide nanop ...
DOI:
10.1016/j.scitotenv.2017.05.170

655. Fast and quantitative determination of saxitoxin and neosaxitoxin in urine by ultra performance liquid chromatography-triple quadrupole mass spectrometry based on the cleanup of solid phase extraction with hydrophilic interaction mechanism B Analytical technologies in the biomedical and life sciences

Author:
Xu, Xiao-min; Huang, Bai-fen; Xu, Jiao-jiao; Cai, Zeng-xuan; Zhang, Jing; Chen, Qing; Han, Jian-Long
Source:
Journal of chromatography 2018 v.1072 pp. 267-272
ISSN:
1570-0232
Subject:
toxins,   etc   ; acetonitrile; correlation; detection limit; hydrophilic interaction chromatography; liquids; mass spectrometry; methanol; patients; poisoning; polyamides; quantitative analysis; solid phase extraction; urine;     Show all 14 Subjects
Abstract:
... Saxitoxin (STX) and neosaxitoxin (NEO) are water-soluble toxins and their cleanup in bio-matrix is a hot topic but difficult problem. A fast and quantitative determination method for STX and NEO in urine was developed using ultra performance liquid chromatography-triple quadrupole mass spectrometry (LC–MS/MS) based on the cleanup of solid phase extraction (SPE) with hydrophilic interaction (HILIC) ...
DOI:
10.1016/j.jchromb.2017.11.032

656. Susceptibility and immune response of Catarina scallop (Argopecten ventricosus) against Vibrio parahaemolyticus, the causative agent of AHPND in shrimp

Author:
Mendoza-Maldonado, Gabriela B.; Diarte-Plata, Genaro; Luna-González, Antonio; Escamilla-Montes, Ruth; Rodríguez-Jaramillo, Carmen; Ruiz-Verdugo, César A.; Fierro Coronado, Jesús A.; Robles-Mungaray, Miguel
Source:
Aquaculture 2018 v.482 pp. 24-30
ISSN:
0044-8486
Subject:
toxins,   etc   ; Argopecten ventricosus; Vibrio parahaemolyticus; adults; bacteria; bioassays; diet; enzyme activity; hemocytes; histopathology; immune response; lethal concentration 50; microalgae; monophenol monooxygenase; mortality; muscles; scallops; seeds; shellfish; shrimp;     Show all 20 Subjects
Abstract:
... Susceptibility and immune response of Argopecten ventricosus challenged with Vibrio parahaemolyticus were determined. Mortality and median lethal concentration of V. parahaemolyticus were assessed in scallop seeds and adults challenged by immersion. Histopathological analysis was done in adults challenged by immersion. The immune response was analyzed in adults by injecting heat-inactivated bacter ...
DOI:
10.1016/j.aquaculture.2017.09.018

657. Affinity capillary electrophoresis for the assessment of binding affinity of carbohydrate‐based cholera toxin inhibitors

Author:
Aizpurua‐Olaizola, Oier; Sastre Torano, Javier; Pukin, Aliaksei; Fu, Ou; Boons, Geert Jan; de Jong, Gerhardus J.; Pieters, Roland J.
Source:
Electrophoresis 2018 v.39 no.2 pp. 344-347
ISSN:
0173-0835
Subject:
cholera toxin,   etc   ; adsorption; binding capacity; capillary electrophoresis; cholera; coatings; diarrhea; dissociation; drugs; gangliosides; glycomics; hemagglutinins; influenza; inhibitory concentration 50; ligands; pH;     Show all 16 Subjects
Abstract:
... Developing tools for the study of protein carbohydrate interactions is an important goal in glycobiology. Cholera toxin inhibition is an interesting target in this context, as its inhibition may help to fight against cholera. For the study of novel ligands an affinity capillary electrophoresis (ACE) method was optimized and applied. The method uses unlabeled cholera toxin B‐subunit (CTB) and unlab ...
DOI:
10.1002/elps.201700207

658. Caffeic acid-assisted cross-linking catalyzed by polyphenol oxidase decreases the allergenicity of ovalbumin in a Balb/c mouse model

Author:
Tong, Ping; Chen, Shuguang; Gao, Jinyan; Li, Xin; Wu, Zhihua; Yang, Anshu; Yuan, Juanli; Chen, Hongbing
Source:
Food and chemical toxicology 2018 v.111 pp. 275-283
ISSN:
0278-6915
Subject:
cholera toxin,   etc   ; adjuvants; allergenicity; allergens; animal models; antibodies; blood serum; catechol oxidase; crosslinking; diarrhea; duodenum; egg albumen; eggs; histamine; histology; hypersensitivity; immunoglobulin E; immunoglobulin G; interferon-gamma; interleukin-13; interleukin-4; interleukin-5; mast cells; mice; ovalbumin; toxicology;     Show all 26 Subjects
Abstract:
... Ovalbumin (OVA) is the most abundant egg white protein, but is also a major egg allergen. Desensitization of OVA may be a good way to control an egg allergy. In this study, caffeic acid-assisted cross-linked OVA catalyzed by polyphenol oxidase (PPO) was prepared, the effect of cross-linking on the allergenicity of OVA was tested in a Balb/c mouse model. Mice were orally sensitized with OVA or cros ...
DOI:
10.1016/j.fct.2017.11.026

659. Combined effect of temperature and nutritional regime on the elimination of the lipophilic toxin okadaic acid in the naturally contaminated wedge shell Donax trunculus

Author:
Botelho, Maria João; Vale, Carlos; Joaquim, Sandra; Costa, Sara T.; Soares, Florbela; Roque, Claúdia; Matias, Domitília
Source:
Chemosphere 2018 v.190 pp. 166-173
ISSN:
0045-6535
Subject:
toxins,   etc   ; chemical composition; coastal water; diet; gametogenesis; glycogen; microalgae; mortality; okadaic acid; starvation; tissues; water temperature;     Show all 12 Subjects
Abstract:
... The influence of nutritional regime and water temperature on depuration rates of OA-group toxins in the wedge shell Donax trunculus was examined by exposing naturally contaminated specimens to three nutritional regimes (microalgae, commercial paste of microalgae, and starvation) for 14 days at 16 °C and 20 °C. Total OA was quantified in the whole soft tissues of the individuals collected in days 2 ...
DOI:
10.1016/j.chemosphere.2017.09.100

660. Criticism of EFSA's scientific opinion on combinatorial effects of ‘stacked’ GM plants

Author:
Bøhn, Thomas
Source:
Food and chemical toxicology 2018 v.111 pp. 268-274
ISSN:
0278-6915
Subject:
toxins,   etc   ; biodiversity; chemical residues; food chain; genetically modified plants; glyphosate; health effects assessments; herbicide resistance; insect resistance; issues and policy; nontarget organisms; risk; toxicity; toxicology;     Show all 14 Subjects
Abstract:
... Recent genetically modified plants tend to include both insect resistance and herbicide tolerance traits. Some of these ’stacked’ GM plants have multiple Cry-toxins expressed as well as tolerance to several herbicides. This means that non-target organisms in the environment (biodiversity) will be co-exposed to multiple stressors simultaneously. A similar co-exposure may happen to consumers through ...
DOI:
10.1016/j.fct.2017.11.023

661. Detection of Shiga toxin-producing Escherichia coli (STEC) in ground beef and bean sprouts: Evaluation of culture enrichment conditions

Author:
Amagliani, Giulia; Rotundo, Luca; Carloni, Elisa; Omiccioli, Enrica; Magnani, Mauro; Brandi, Giorgio; Fratamico, Pina
Source:
Food research international 2018 v.103 pp. 398-405
ISSN:
0963-9969
Subject:
Shiga toxin-producing Escherichia coli,   etc   ; bacteria; bean sprouts; cefsulodin; culture media; food contamination; food matrix; genes; ground beef; mung beans; novobiocin; quantitative polymerase chain reaction; serotypes; temperature; vancomycin;     Show all 15 Subjects
Abstract:
... The main purpose of this work was to evaluate culture enrichment conditions, with particular regard to those reported in ISO/TS 13136:2012, for STEC detection in food. The culture media evaluated included mTSB with novobiocin 0–16mg/l (mTSB+N0–16) or acriflavin 12mg/l (mTSB+A12); BPW; mBPWp with acriflavin 10mg/l, cefsulodin 10mg/l, vancomycin 8mg/l (mBPWp+ACV); and mBPWp with cefsulodin 10mg/l, v ...
DOI:
10.1016/j.foodres.2017.10.059

662. Expression of recombinant α-toxin BmKM9 from scorpion Buthus martensii Karsch and its functional characterization on sodium channels

Author:
Yang, Fan; Liu, Shuang; Zhang, Yaoyun; Qin, Chenhu; Xu, Lingna; Li, Wenhua; Cao, Zhijian; Li, Wenxin; Wu, Yingliang
Source:
Peptides 2018 v.99 pp. 153-160
ISSN:
0196-9781
Subject:
toxins,   etc   ; Buthus martensii; amino acids; disulfide bonds; dose response; drugs; functional properties; genetic engineering; median effective concentration; medicinal properties; scorpion venoms; sodium channels; thrombin;     Show all 13 Subjects
Abstract:
... Scorpion toxins are invaluable pharmacological tools for studying ion channels and potential drugs for channelopathies. The long-chain toxins from scorpion venom with four disulfide bridges exhibit their unusual bioactivity or biotoxicity by acting on the sodium channels. However, the functional properties of most toxins are still unclear due to their tiny amounts in crude venom and their challeng ...
DOI:
10.1016/j.peptides.2017.09.017

663. First report of paralytic shellfish poisoning (PSP) caused by Alexandrium tamiyavanichii in Kuantan Port, Pahang, East Coast of Malaysia

Author:
Mohammad‐Noor, Normawaty; Adam, Aimimuliani; Lim, Po T.; Leaw, Chui P.; Lau, Winnie L.S.; Liow, Guat R.; Muhamad‐Bunnori, Noraslinda; Hamdan, Nurul‐Ashima; Md‐Nor, Azlan; Kemat, Norazizah; Muniandi, Devaraj
Source:
Phycological research 2018 v.66 no.1 pp. 37-44
ISSN:
1322-0829
Subject:
toxins,   etc   ; Alexandrium; algae; algal blooms; coastal water; coasts; fluorescence microscopes; high performance liquid chromatography; humans; internal transcribed spacers; paralytic shellfish poisoning; people; public health; shellfish; toxicity; transcription (genetics); Malaysia;     Show all 17 Subjects
Abstract:
... Harmful algal bloom (HAB) is a proliferation of algae, which naturally produce biotoxins and cause harmful effects to humans, the environment and organisms associated with it. Paralytic shellfish poisoning (PSP) was reported for the first time in Kuantan Port, Pahang, Malaysia, in November 2013, followed by a second episode in August 2014. The toxicity level reported during the second event was as ...
DOI:
10.1111/pre.12205

664. Genetic diversity and toxin gene distribution among serovars of Actinobacillus pleuropneumoniae from Australian pigs

Author:
Yee, S; Blackall, PJ; Turni, C
Source:
Australian veterinary journal 2018 v.96 no.1-2 pp. 17-23
ISSN:
0005-0423
Subject:
bacterial toxins,   etc   ; Actinobacillus pleuropneumoniae; farms; genes; genetic variation; pathogenicity; polymerase chain reaction; repetitive sequences; serotypes; swine; Australia;     Show all 11 Subjects
Abstract:
... OBJECTIVE: To explore the diversity among isolates of the Actinobacillus pleuropneumoniae serovars most common in Australia (serovars 1, 5, 7 and 15) and to examine the Apx toxin profiles in selected representative isolates. DESIGN: A total of 250 isolates selected from different farms were examined for their genotypic profiles and a subset of 122 isolates for their toxin profiles. METHODS: The is ...
DOI:
10.1111/avj.12660

665. MDR1 gene C3435T polymorphism in chronic hepatitis C patients

Author:
Parsa Nahad, Mehdi; Makvandi, Manoochehr; Teimoori, Ali; Jalilian, Shahram; Kayedani, Gholam Abbas; Mahmoodi, Sara
Source:
Microbial pathogenesis 2018 v.114 pp. 63-67
ISSN:
0882-4010
Subject:
toxins,   etc   ; DNA; P-glycoproteins; alleles; cell membranes; chronic hepatitis C; drug resistance; drugs; females; gene expression; genotyping; heterozygosity; homozygosity; males; patients; polymerase chain reaction; restriction fragment length polymorphism; single nucleotide polymorphism; therapeutics; xenobiotics;     Show all 20 Subjects
Abstract:
... MDR1 is a highly polymorphic gene that encodes P-glycoprotein (P-gp). This protein anchor to the cell membrane and transports toxins, xenobiotic, chemicals, and drugs from the intracellular to extracellular and thus protect cells. Polymorphism of the MDR1 gene seems to be effective in gene expression and response to treatment. Since one of the main mechanisms of drug resistance is the removal of t ...
DOI:
10.1016/j.micpath.2017.11.017

666. Nisin-induced expression of recombinant T cell epitopes of major Japanese cedar pollen allergens in Lactococcus lactis

Author:
Van Hoang, Vinh; Ochi, Takahumi; Kurata, Kentaro; Arita, Yutaka; Ogasahara, Yusuke; Enomoto, Keiichi
Source:
Applied microbiology and biotechnology 2018 v.102 no.1 pp. 261-268
ISSN:
0175-7598
Subject:
cholera toxin,   etc   ; Cryptomeria japonica; Escherichia; GRAS substances; Lactococcus lactis; T-lymphocytes; Western blotting; adjuvants; allergens; antibodies; antimicrobial peptides; edible vaccines; epitopes; genes; genetic vectors; hay fever; nisin; plasmids; pollen;     Show all 19 Subjects
Abstract:
... Japanese cedar pollinosis is a seasonal allergic disease caused by two major pollen allergens: Cry j 1 and Cry j 2 antigens. To develop an oral vaccine to treat pollinosis, we constructed recombinant Lactococcus lactis harboring the gene encoding fused T cell epitopes from the Cry j 1 and Cry j 2 antigens. The recombinant T cell epitope peptide was designed to contain the fused cholera toxin B sub ...
DOI:
10.1007/s00253-017-8579-8

667. Occurrence and diversity of Bacillus cereus and moulds in spices and herbs

Author:
Fogele, Baiba; Granta, Rita; Valciņa, Olga; Bērziņš, Aivars
Source:
Food control 2018 v.83 pp. 69-74
ISSN:
0956-7135
Subject:
toxins,   etc   ; Aspergillus; Bacillus cereus; Penicillium; cumin; curry; food spoilage; genes; herbs; hygiene; markets; microbiological criteria; molds (fungi); packaging; pepper; shelf life; spore-forming bacteria; temperature;     Show all 18 Subjects
Abstract:
... Spices and herbs can contain toxin-producing bacteria and moulds, which can cause health problems for consumers and contribute to food spoilage and shelf-life reduction. The aims of the present work were (i) to determine the occurence and levels of B. cereus and moulds; (ii) to charactize the incidence and diversity of B. cereus emetic toxin (ces, CER), and diarrhoeal toxin-encoding genes (entFM, ...
DOI:
10.1016/j.foodcont.2017.05.038

668. Pesticidal prospectives of chitinolytic bacteria in agricultural pest management

Author:
Subbanna, A.R.N.S.; Rajasekhara, H.; Stanley, J.; Mishra, K.K.; Pattanayak, A.
Source:
Soil biology & biochemistry 2018 v.116 pp. 52-66
ISSN:
0038-0717
Subject:
toxins,   etc   ; Nematoda; bacteria; biological control agents; branches; chitin; chitinase; genes; genetically modified organisms; insect pests; metabolism; parasites; pathogenicity; phytophagous insects; plant pathogenic fungi; plant protection; production technology; synergism;     Show all 18 Subjects
Abstract:
... Chitin metabolism is an essential life sustaining activity of phytophagous insects, phytopathogenic fungi and parasitic nematode which are the major limiting factors of agricultural production systems. Diverse bacteria, although non-chitinous life forms, are reported to degrade native chitin associated with the pestiferous organisms thereby exerting pathogenicity. So, the deployment of chitinolyti ...
DOI:
10.1016/j.soilbio.2017.09.019

669. Predominant mycotoxins, mycotoxigenic fungi and climate change related to wine

Author:
Paterson, R. Russell M.; Venâncio, Armando; Lima, Nelson; Guilloux-Bénatier, Michèle; Rousseaux, Sandrine
Source:
Food research international 2018 v.103 pp. 478-491
ISSN:
0963-9969
Subject:
T-2 toxin,   etc   ; Alternaria; Aspergillus carbonarius; Aspergillus niger; aflatoxins; climate; climate change; fumonisins; fungi; good agricultural practices; grapes; models; ochratoxin A; patulin; temperature; vines; white wines; France; Italy; Southern European region; Spain;     Show all 21 Subjects
Abstract:
... Wine is a significant contributor to the economies of many countries. However, the commodity can become contaminated with mycotoxins produced by certain fungi. Most information on mycotoxins in wine is from Spain, Italy and France. Grapes can be infected by mycotoxigenic fungi, of which Aspergillus carbonarius producing ochratoxin A (OTA) is of highest concern. Climate is the most important factor ...
DOI:
10.1016/j.foodres.2017.09.080

670. Processing of mycotoxin contaminated waste streams through anaerobic digestion

Author:
De Gelder, L.; Audenaert, K.; Willems, B.; Schelfhout, K.; De Saeger, S.; De Boevre, M.
Source:
Waste management 2018 v.71 pp. 122-128
ISSN:
0956-053X
Subject:
T-2 toxin,   etc   ; aflatoxin B1; anaerobic digestion; biogas; corn; deoxynivalenol; digestion; ergot alkaloids; feedstocks; fumonisin B1; guidelines; methane; methane production; ochratoxin A; organic wastes; streams; thermophilic microorganisms; waste management; zearalenone;     Show all 19 Subjects
Abstract:
... Food and feed stocks heavily contaminated with mycotoxins are rendered unfit for consumption and therefore discarded as waste. Due to the lack of guidelines and in accordance with the prudent avoidance principle, these waste streams are often incinerated. For better valorization, these streams could be used as input for anaerobic digestion. However, the degradation of multiple mycotoxins during an ...
DOI:
10.1016/j.wasman.2017.09.039

671. Recent advances in the application of capillary electromigration methods for food analysis and Foodomics

Author:
Álvarez, Gerardo; Montero, Lidia; Llorens, Laura; Castro‐Puyana, María; Cifuentes, Alejandro
Source:
Electrophoresis 2018 v.39 no.1 pp. 136-159
ISSN:
0173-0835
Subject:
toxins,   etc   ; amino acids; bioactive properties; biogenic amines; carbohydrates; electrophoresis; food additives; food analysis; food processing; foodomics; heterocyclic amines; inorganic compounds; lipids; monitoring; nutritive value; peptides; pesticides; pigments; polyphenols; proteins; vitamins;     Show all 21 Subjects
Abstract:
... This review work presents and discusses the main applications of capillary electromigration methods in food analysis and Foodomics. Papers that were published during the period February 2015‐February 2017 are included following the previous review by Acunha et al. (Electrophoresis 2016, 37, 111–141). The paper shows the large variety of food related molecules that have been analyzed by CE includin ...
DOI:
10.1002/elps.201700321

672. Seasonal dynamics of freshwater pathogens as measured by microarray at Lake Sapanca, a drinking water source in the north-eastern part of Turkey

Author:
Akçaalan, Reyhan; Albay, Meric; Koker, Latife; Baudart, Julia; Guillebault, Delphine; Fischer, Sabine; Weigel, Wilfried; Medlin, LindaK.
Source:
Environmental monitoring and assessment 2018 v.190 no.1 pp. 42
ISSN:
0167-6369
Subject:
cyanobacterial toxins,   etc   ; European Union; barcoding; drinking water; filters; human health; humans; lakes; microarray technology; monitoring; pathogens; public health; risk; water microbiology; water quality; Turkey (country);     Show all 16 Subjects
Abstract:
... Monitoring drinking water quality is an important public health issue. Two objectives from the 4 years, six nations, EU Project μAqua were to develop hierarchically specific probes to detect and quantify pathogens in drinking water using a PCR-free microarray platform and to design a standardised water sampling program from different sources in Europe to obtain sufficient material for downstream a ...
DOI:
10.1007/s10661-017-6314-7

673. Short communication: Analysis of mycotoxins in Spanish milk

Author:
Flores-Flores, Myra Evelyn; González-Peñas, Elena
Source:
Journal of dairy science 2018 v.101 no.1 pp. 113-117
ISSN:
0022-0302
Subject:
HT-2 toxin,   etc   ; 15-acetyldeoxynivalenol; European Union; acetonitrile; aflatoxin M1; animal and human health; deoxynivalenol; detection limit; diacetoxyscirpenol; diet; fumonisins; high performance liquid chromatography; liquid-liquid extraction; milk; monitoring; neosolaniol; nivalenol; ochratoxins; separation; sodium acetate; spectrometers; sterigmatocystin; toxicity; zearalenone;     Show all 24 Subjects
Abstract:
... We surveyed the presence of 22 mycotoxins in 191 Spanish cow milk samples. Mycotoxins could be carried over from diet into animal milk and have toxic effects on human and animal health. The interaction of different mycotoxins may be additive or synergetic. Therefore, surveillance of mycotoxin co-occurrence in milk is recommended. Aflatoxins M1, B1, B2, G1, and G2, ochratoxins A and B, nivalenol, d ...
DOI:
10.3168/jds.2017-13290

674. Structure, folding and stability of a minimal homologue from Anemonia sulcata of the sea anemone potassium channel blocker ShK

Author:
Krishnarjuna, Bankala; MacRaild, Christopher A.; Sunanda, Punnepalli; Morales, Rodrigo A.V.; Peigneur, Steve; Macrander, Jason; Yu, Heidi H.; Daly, Marymegan; Raghothama, Srinivasarao; Dhawan, Vikas; Chauhan, Satendra; Tytgat, Jan; Pennington, Michael W.; Norton, Raymond S.
Source:
Peptides 2018 v.99 pp. 169-178
ISSN:
0196-9781
Subject:
toxins,   etc   ; Anthozoa; Artemia; Palaemonetes; cysteine; electrophysiology; nauplii; nuclear magnetic resonance spectroscopy; peptides; potassium channels; proteolysis; toxicity; transcriptomics;     Show all 13 Subjects
Abstract:
... Peptide toxins elaborated by sea anemones target various ion-channel sub-types. Recent transcriptomic studies of sea anemones have identified several novel candidate peptides, some of which have cysteine frameworks identical to those of previously reported sequences. One such peptide is AsK132958, which was identified in a transcriptomic study of Anemonia sulcata and has a cysteine framework simil ...
DOI:
10.1016/j.peptides.2017.10.001

675. The defensive aphid symbiont Hamiltonella defensa affects host quality differently for Aphelinus glycinis versus Aphelinus atriplicis

Author:
Hopper, Keith R.; Kuhn, Kristen L.; Lanier, Kathryn; Rhoades, Joshua H.; Oliver, Kerry M.; White, Jennifer A.; Asplen, Mark K.; Heimpel, George E.
Source:
Biological control 2018 v.116 pp. 3-9
ISSN:
1049-9644
Subject:
toxins,   etc   ; Acyrthosiphon pisum; Aphelinus glycinis; Aphis craccivora; Braconidae; adults; bacteria; bacteriophages; eggs; embryogenesis; endosymbionts; females; hosts; microsymbionts; parasitism; parasitoids; progeny;     Show all 17 Subjects
Abstract:
... Endosymbiont interactions with hosts have important effects on fitness, including the fitness of many pest and beneficial species. Among these interactions, facultative endosymbiotic bacteria can protect aphids from parasitoids. Aphis craccivora and Acyrthosiphon pisum can harbor the symbiotic bacteria Hamiltonella defensa and its bacteriophage APSE. Infection by H. defensa defends these aphids ag ...
Datasets:
  Data from: Defensive aphid symbiont Hamiltonella defensa effects on Aphelinus glycinis and Aphelinus atriplicis
DOI:
10.1016/j.biocontrol.2017.05.008

676. Transcriptome and toxin family analysis of the paralysis tick, Ixodes holocyclus

Author:
Rodriguez-Valle, Manuel; Moolhuijzen, Paula; Barrero, Roberto A.; Ong, Chian Teng; Busch, Greta; Karbanowicz, Thomas; Booth, Mitchell; Clark, Richard; Koehbach, Johannes; Ijaz, Hina; Broady, Kevin; Agnew, Kim; Knowles, Aleta G.; Bellgard, Matthew I.; Tabor, Ala E.
Source:
International journal for parasitology 2018 v.48 no.1 pp. 71-82
ISSN:
0020-7519
Subject:
toxins,   etc   ; Ixodes holocyclus; cats; complementary DNA; control methods; databases; distress; dogs; females; neonates; neurotoxicity; paralysis; rats; saliva; salivary glands; synaptosomes; ticks; transcriptome;     Show all 18 Subjects
Abstract:
... The Australian paralysis tick (Ixodes holocyclus) secretes neuropathic toxins into saliva that induce host paralysis. Salivary glands and viscera were dissected from fully engorged female I. holocyclus ticks collected from dogs and cats with paralysis symptoms. cDNA from both tissue samples were sequenced using Illumina HiSeq 100 bp pair end read technologies. Unique and non-redundant holocyclotox ...
DOI:
10.1016/j.ijpara.2017.07.007

677. Virulence of entomopathogenic bacteria in the bed bug, Cimex lectularius

Author:
Pietri, Jose E.; Liang, Dangsheng
Source:
Journal of invertebrate pathology 2018 v.151 pp. 1-6
ISSN:
0022-2011
Subject:
toxins,   etc   ; Bacillus thuringiensis subsp. israelensis; Cimex lectularius; Pseudomonas fluorescens; Serratia marcescens; biological control; entomopathogenic bacteria; humans; insect pests; insecticide resistance; mortality; pesticides; temperature; viability; virulence;     Show all 15 Subjects
Abstract:
... Due in part to the development of insecticide resistance, the common bed bug, Cimex lectularius, has overcome human intervention efforts to make a global resurgence. The failure of chemical pesticides has created a need for novel strategies to combat bed bugs. While a number of insect pests are susceptible to the use of entomopathogenic microbes or microbial-derived toxins, biological control meth ...
DOI:
10.1016/j.jip.2017.10.004

678. A methodology for detecting the wound state sensing in terms of its colonization of pathogenic bacteria

Author:
Zhou, Jin; Yao, Danyu; Qian, Zhiyong; Hou, Sen; Li, Linhao; Fan, Yubo
Source:
MethodsX 2018 v.5 pp. 1521-1527
ISSN:
2215-0161
Subject:
bacterial toxins,   etc   ; Escherichia coli; Pseudomonas aeruginosa; Staphylococcus aureus; biomimetics; dyes; enzymes; fluorescence; virulent strains;     Show all 9 Subjects
Abstract:
... A methodology for wound state sensing in terms of its colonization with pathogenic bacteria such as Staphylococcus aureus or Pseudomonas aeruginosa has been developed. Here we report polydiacetylene (PDA) liposomes containing self-quenched carboxyfluorescein dye are only sensitive to toxins/enzymes secreted by Pathogenic bacteria but not by non-pathogenic species of Escherichia coli (DH5α). The ba ...
DOI:
10.1016/j.mex.2018.11.012

679. Combined proteomic and functional analysis reveals rich sources of protein diversity in skin mucus and venom from the Scorpaena plumieri fish

Author:
Borges, Márcia H.; Andrich, Filipe; Lemos, Pedro H.; Soares, Thiago G.; Menezes, Thiago N.; Campos, Fabiana V.; Neves, Leandro X.; Castro-Borges, William; Figueiredo, Suely G.
Source:
Journal of proteomics 2018
ISSN:
1874-3919
Subject:
toxins,   etc   ; Scorpaena plumieri; antimicrobial properties; bioactive compounds; fish; hyaluronoglucosaminidase; lectins; mucus; protein composition; proteinase inhibitors; proteinases; proteolysis; proteomics; toxicity; venoms;     Show all 15 Subjects
Abstract:
... The biological activities observed upon envenomation by Scorpaena plumieri could be linked to both the venom and the skin mucus. Through a proteomic/functional approach we analyzed protein composition and biological activities of the venom and skin mucus. We identified 885 proteins: 722 in the Venomous Apparatus extracts (Sp-VAe) and 391 in the Skin Mucus extract (Sp-SMe), with 494 found exclusive ...
DOI:
10.1016/j.jprot.2018.08.002

680. Compositional and functional investigation of individual and pooled venoms from long-term captive and recently wild-caught Bothrops jararaca snakes

Author:
Galizio, Nathália da Costa; Serino-Silva, Caroline; Stuginski, Daniel Rodrigues; Abreu, Patrícia Antônia Estima; Sant'Anna, Sávio Stefanini; Grego, Kathleen Fernandes; Tashima, Alexandre Keiji; Tanaka-Azevedo, Anita Mitico; Morais-Zani, Karen de
Source:
Journal of proteomics 2018
ISSN:
1874-3919
Subject:
toxins,   etc   ; Bothrops jararaca; antivenoms; coagulants; enzyme activity; intraspecific variation; protein composition; proteolysis; proteomics; reversed-phase high performance liquid chromatography; snake bites; snake venoms; snakes; Brazil;     Show all 14 Subjects
Abstract:
... Intraspecific venom variability has been extensively reported in a number of species and is documented to be the result of several factors. However, current evidence for snake venom variability related to captivity maintenance is controversial. Here we report a compositional and functional investigation of individual and pooled venoms from long-term captive (LTC) and recently wild-caught (RWC) B. ...
DOI:
10.1016/j.jprot.2018.07.007

681. Co-occurrence of mcr-1, mcr-4 and mcr-5 genes in multidrug-resistant ST10 Enterotoxigenic and Shiga toxin-producing Escherichia coli in Spain (2006-2017)

Author:
García, Vanesa; García-Meniño, Isidro; Mora, Azucena; Flament-Simon, Saskia C.; Díaz-Jiménez, Dafne; Blanco, Jesús E.; Alonso, María Pilar; Blanco, Jorge
Source:
International journal of antimicrobial agents 2018
ISSN:
0924-8579
Subject:
Shiga toxin-producing Escherichia coli,   etc   ; colistin; diarrhea; enterotoxigenic Escherichia coli; farms; food animals; geographical distribution; human health; multiple drug resistance; polypeptides; resistance genes; risk; swine production; Spain;     Show all 14 Subjects
Abstract:
... Colistin is an antimicrobial polypeptide commonly employed for controlling and treating neonatal and post-weaning diarrhoea (PWD) diseases caused by Enterotoxigenic and Shiga toxin-producing Escherichia coli (ETEC and STEC). The plasmid-mediated colistin resistance gene, mcr-1 was first described in late 2015 and, since then, multiple studies have reported its global distribution. In addition, fiv ...
DOI:
10.1016/j.ijantimicag.2018.03.022

682. Effect of Lactobacillus Rhamnosus on serum uremic toxins (phenol and P-Cresol) in hemodialysis patients: A double blind randomized clinical trial

Author:
Eidi, Farzad; Poor -reza Gholi, Fatemeh; Ostadrahimi, Alireza; Dalili, Nooshin; Samadian, Fariba; Barzegari, Abolfazl
Source:
Clinical nutrition ESPEN 2018
ISSN:
2405-4577
Subject:
toxins,   etc   ; Lactobacillus rhamnosus; blood serum; carbohydrates; clinical trials; computer software; dialysis; energy intake; females; hemodialysis; males; mortality; p-cresol; patients; placebos; probiotics; protein intake; regression analysis; sodium; t-test;     Show all 20 Subjects
Abstract:
... Uremic toxins such as p-cresol and phenol are suggested to be associated with higher mortality in hemodialysis patients. The aim of this study was to investigate the effects of probiotics on some serum uremic toxin levels in hemodialysis patients.Patients undergoing hemodialysis in a university dialysis center were enrolled in this randomized controlled double blind clinical trial. The patients re ...
DOI:
10.1016/j.clnesp.2018.08.010

683. Effects on skin of Stichopus japonicus viscera extracts detected with saponin including Holothurin A: Down-regulation of Melanin Synthesis and Up-regulation of Neocollagenesis Mediated by ERK Signaling Pathway

Author:
Kwon, Tae-Rin; Oh, Chang Taek; Bak, Dong-Ho; Kim, Jong Hwan; Seok, Joon; Lee, Jong Hoon; Lim, Su Hwan; Yoo, Kwang Ho; Kim, Beom Joon; Kim, Heesu
Source:
Journal of ethnopharmacology 2018
ISSN:
0378-8741
Subject:
toxins,   etc   ; Apostichopus japonicus; Western blotting; animal organs; anti-aging properties; artificial skin; collagen; enzyme activity; enzyme inhibition; fibroblasts; freeze drying; immunocytochemistry; melanin; melanogenesis; mitogen-activated protein kinase; models; mushrooms; pain; phosphorylation; saponins; signal transduction; tissue repair; traditional foods; traditional medicine; viability; Asia;     Show all 26 Subjects
Abstract:
... Stichopus japonicus (sea cucumber), edible traditional food in Asia, and its extracts are renowned for their wound healing, pain relieving, and cosmetic effects in traditional medicine. Holothurins, toxins isolated from sea cucumber, are thought to be active components for their beneficial effects. However, researchers have yet to outline specific mechanisms thereof.The present study was designed ...
DOI:
10.1016/j.jep.2018.08.007

684. El Niño Range Extensions of Pacific Sand Crab (Emerita analoga) in the Northeastern Pacific

Author:
Wonham, Marjorie J.; Hart, Michael W.
Source:
Northwest science 2018 v.92 no.1 pp. 53-60
ISSN:
0029-344X
Subject:
toxins,   etc   ; Acanthocephala; El Nino; Emerita; Enhydra lutris; algal blooms; beaches; birds; climate; climate change; coastal water; crabs; fauna; fish; intermediate hosts; mammals; mortality; parasites; Alaska; British Columbia; California; Oregon; Washington (state);     Show all 23 Subjects
Abstract:
... Many marine species are shifting poleward with global climate change, and many move on a shorter-term basis with periodic climate variations such as the El Niño Southern Oscillation (ENSO) and Pacific Decadal Oscillation (PDO). The Pacific sand crab Emerita analoga (Crustacea: Decapoda: Anomura: Hippidae) is a dominant member of the wave-exposed sandy beach macrofauna of California and Oregon. Its ...
DOI:
10.3955/046.092.0106

685. Integrated LAMP and immunoassay platform for diarrheal disease detection

Author:
Phaneuf, C.R.; Mangadu, B.; Tran, H.M.; Light, Y.K.; Sinha, A.; Charbonier, F.W.; Eckles, T.P.; Singh, A.K.; Koh, C.-Y.
Source:
Biosensors & bioelectronics 2018
ISSN:
0956-5663
Subject:
Shiga-like toxin 1; cholera toxin,   etc   ; Escherichia coli; Salmonella Typhimurium; bacteria; biosensors; detection limit; diagnostic techniques; diarrhea; disease detection; enterotoxins; heating systems; immunoassays; infectious diseases; instrumentation; intestinal microorganisms; nucleic acids; point-of-care systems; screening;     Show all 19 Subjects
Abstract:
... The challenges of diagnosing infectious disease, especially in the developing world, and the shortcomings of available instrumentation have exposed the need for portable, easy-to-use diagnostic tools capable of detecting the wide range of causative microbes while operating in low resource settings. We present a centrifugal microfluidic platform that combines ultrasensitive immunoassay and isotherm ...
DOI:
10.1016/j.bios.2018.08.005

686. Pharmacoinformatic Approach to Explore the Antidote Potential of Phytochemicals on Bungarotoxin from Indian Krait, Bungarus caeruleus

Author:
Rajendran, Barani Kumar; Xavier Suresh, M.; Bhaskaran, Shanmuga Priya; Harshitha, Yarradoddi; Gaur, Uma; Kwok, Hang Fai
Source:
Computational and Structural Biotechnology Journal 2018 v.16 pp. 450-461
ISSN:
2001-0370
Subject:
toxins,   etc   ; Bungarus; adverse effects; antidotes; benzene; biotechnology; blood coagulation; butyric acid; chemical constituents of plants; coagulation; dermatitis; eugenol; hemorrhage; humans; medicinal plants; models; molecular dynamics; mortality; necrosis; nerolidol; neurotoxicity; paralysis; propionic acid; proteins; snakes; venoms; India;     Show all 27 Subjects
Abstract:
... Venomous reptiles especially serpents are well known for their adverse effects after accidental conflicts with humans. Upon biting humans these serpents transmit arrays of detrimental toxins with diverse physiological activities that may either lead to minor symptoms such as dermatitis and allergic response or highly severe symptoms such as blood coagulation, disseminated intravascular coagulation ...
DOI:
10.1016/j.csbj.2018.10.005

687. Phyto-miRNAs-based regulation of metabolites biosynthesis in medicinal plants

Author:
Sabzehzari, M.; Naghavi, M.R.
Source:
Gene 2018
ISSN:
0378-1119
Subject:
toxins,   etc   ; RNA interference; biochemical pathways; biosynthesis; biotechnology; drugs; dyes; genes; industry; insecticides; medicinal plants; medicine; metabolic engineering; microRNA; non-coding RNA; secondary metabolites; signal transduction;     Show all 17 Subjects
Abstract:
... Medicinal plants, are known to produce a wide range of plant secondary metabolites (PSMs) applied as insecticides, drugs, dyes and toxins in agriculture, medicine, industry and bio-warfare plus bio-terrorism, respectively. However, production of PSMs is usually in small quantities, so we need to find novel ways to increase both quantity and quality of them. Fortunately, biotechnology suggests seve ...
DOI:
10.1016/j.gene.2018.09.049

688. Synthesis of peptide based epsilon toxin vaccine by covalent anchoring to tetanus toxoid

Author:
Kaushik, Himani; Dixit, Aparna; Garg, Lalit C.
Source:
Anaerobe 2018
ISSN:
1075-9964
Subject:
toxins,   etc   ; Clostridium perfringens; Haemophilus; Neisseria; Streptococcus; amino acids; antibodies; antiserum; death; edema; enterotoxemia; enzyme-linked immunosorbent assay; immune response; influenza; lethal dose; mice; neutralization; peptides; pneumonia; propionic acid; subunit vaccines; tetanus; vaccination;     Show all 23 Subjects
Abstract:
... The epsilon toxin (Etx) produced by Clostridium perfringens type B and D causes severe enterotoxaemia associated with a general edema and neurological alterations, leading to subsequent death and is listed as one of the most lethal toxins. Currently employed vaccines against C. perfringens epsilon toxin include toxoid based vaccines. Use of peptide vaccines has become an interesting approach for v ...
DOI:
10.1016/j.anaerobe.2018.06.008

689. Ultrasensitive sensing of Androctonus australis hector scorpion venom toxins in biological fluids using an electrochemical graphene quantum dots/nanobody-based platform

Author:
Mars, Abdelmoneim; Bouhaouala-Zahar, Balkiss; Raouafi, Noureddine
Source:
Talanta 2018
ISSN:
0039-9140
Subject:
toxins,   etc   ; Androctonus australis; bites and stings; blood serum; detection limit; electrochemistry; electrodes; graphene; humans; neutralization; quantum dots; scorpion venoms; storage quality; toxicity; urine;     Show all 15 Subjects
Abstract:
... Rapid and sensitive detection of low levels of scorpion venom toxins in biological fluids is of tremendous importance for decision-taking in cases of envenomation by scorpions stings. In Tunisia, at least 1200 severe envenomation cases by Androctonus australis hector (Aah) scorpion stings were reported annually. In this work, we report on a novel electrochemical immuno-sandwich to detect the Aah50 ...
DOI:
10.1016/j.talanta.2018.07.087