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1. Viability of microencapsulated Akkermansia muciniphila and Lactobacillus plantarum during freeze-drying, storage and in vitro simulated upper gastrointestinal tract passage

Author:
Marcial-Coba, Martín Sebastián,   et al.   ; Cieplak, Tomasz; Cahú, Thiago Barbosa; Blennow, Andreas; Knøchel, Susanne; Nielsen, Dennis Sandris;     Show all 6 Authors
Source:
Food & function 2018 v.9 no.11 pp. 5868-5879
ISSN:
2042-650X
Subject:
Lactobacillus plantarum; agave syrup; anaerobic conditions; cell viability; cryoprotectants; freeze drying; gellan gum; glucose; humans; intestinal microorganisms; mannitol; microencapsulation; oxygen; peptones; probiotics; protein content; protocols; skim milk; sorbitol; stomach; storage quality; sucrose; temperature; trehalose; xanthan gum; yeast extract
Abstract:
... Akkermansia muciniphila, an abundant member of the human gut microbiota, has been suggested as a potential next-generation probiotic. However, its high sensitivity to oxygen limits the development of dosage protocols. Here, we describe microencapsulation, in a xanthan and gellan gum matrix, and a subsequent freeze-drying protocol for A. muciniphila DSM22959. For comparison Lactobacillus plantarum ...
DOI:
10.1039/c8fo01331d