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- Belser, Jessica A., et al. Show all 6 Authors
- Vaccine 2018 v.36 no.29 pp. 4346-4353
- Baculoviridae; Influenza A virus; avian influenza; enzyme activity; ferrets; hemagglutination; hemagglutinins; immunogenicity; models; pandemic; particle size; sialidase; vaccines; virus-like particles; viruses
- ... During the past decade, H5N1 highly pathogenic avian influenza (HPAI) viruses have diversified genetically and antigenically, suggesting the need for multiple H5N1 vaccines. However, preparation of multiple vaccines from live H5N1 HPAI viruses is difficult and economically not feasible representing a challenge for pandemic preparedness. Here we evaluated a novel multi-clade recombinant H5N1 virus- ...