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- Kimmitt, Beth A., et al. Show all 3 Authors
- American journal of veterinary research 2018 v.79 no.5 pp. 555-561
- Clostridium; EDTA (chelating agent); acetylcysteine; blood serum; calcium; collagenase; cornea; dogs; doxycycline; enzyme inhibition; horses; in vivo studies; minocycline; models; sodium chloride; veterinary medicine
- ... OBJECTIVE To compare the efficacy of various concentrations and combinations of serum, EDTA, 3 tetracyclines, and N-acetylcysteine (NAC) for collagenase inhibition in an in vitro corneal degradation model. SAMPLE Grossly normal corneas from recently euthanized dogs and horses and fresh serum from healthy dogs and horses. PROCEDURES Serum was pooled by species for in vitro use. For each species, se ...