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- Lin, Shumei, et al. Show all 9 Authors
- Amino acids 2018 v.50 no.7 pp. 863-875
- NADH dehydrogenase; antioxidant activity; apoptosis; caspase-3; caspase-9; cytochrome-c oxidase; death domain receptors; ethanol; glutathione peroxidase; hepatocytes; in vitro studies; ligands; liver; liver diseases; malondialdehyde; mitochondria; necrosis; rats; reverse transcriptase polymerase chain reaction; staining; superoxide dismutase; taurine
- ... One pathogenic mechanism of ethanol-induced liver injury is the excessive production of reactive oxygen species (ROS), which may result in alcoholic liver disease (ALD) characterized by cell death due to necrosis and apoptosis. Taurine was proved to protect against liver damage. However, whether taurine attenuates ethanol-induced hepatic apoptosis remains unknown. The present study aims to elucida ...