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- Shi, Jianhui, et al. Show all 6 Authors
- Journal of functional foods 2018 v.49 pp. 412-423
- Western blotting; acetylcysteine; apoptosis; autophagy; beta-lactoglobulin; caspases; cell cycle checkpoints; chemoprevention; hepatoma; human cell lines; milk; neoplasm cells; protein synthesis; selenium; staining; therapeutics; toxicity testing; transmission electron microscopy
- ... β-lactoglobulin is important fraction in bovine milk. Selenium is an essential nutrient element. The apoptosis and autophagy induction of Se-β-Lg combined selenic acid in β-lactoglobulin on Hep G2 and Hep 3B cells were investigated in this study. MTT assay showed Se-β-Lg inhibited cells viability. Annexin V-FITC/PI and PI staining indicated Se-β-Lg triggered cells apoptosis and cell cycle arrest. ...