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- Tang, Weijun, et al. Show all 6 Authors
- Tetrahedron 2018 v.74 no.49 pp. 7040-7046
- aldehydes; byproducts; catalysts; catalytic activity; chemical structure; cyclization reactions; iron
- ... Fe(OTf)2 has been found to be an efficient catalyst for the Oxa-Pictet–Spengler cyclization reaction leading to isochromans. A series of substituted isochromans were obtained with good to excellent isolated yields by coupling β-arylethanols with aldehydes or ketals under the catalysis of 1 mol% of Fe(OTf)2 at 70 °C. Using a cheap, less-toxic catalyst with water as the only byproduct, this iron-cat ...