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- Wei, Jicheng, et al. Show all 9 Authors
- Molecular biology reports 2018 v.45 no.6 pp. 1611-1619
- antagonists; apoptosis; blood serum; growth factors; metabolism; mice; models; muscle development; muscles; muscular atrophy; myoblasts; myotubes; sepsis (infection); skeletal muscle; transcription (genetics); transcription factor NF-kappa B
- ... Sepsis-induced skeletal muscle atrophy is a pathological condition characterized by the loss of strength and muscle mass. Cytokine-induced apoptosis and impaired myogenesis play key roles in the development of this condition. However, the complete underlying mechanism remains largely unknown. Neuregulins are glial growth factors essential for myogenesis that regulate muscle metabolism. We investig ...