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7983-2017
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spectral analysis
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lignans
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- Author:
- Jia Chen; Chun-Chao Zhao; Jian-Hua Shao; Ju-Di Fan; Xu-Hua Huang
- Source:
- Chemistry of natural compounds 2017 v.53 no.4 pp. 626-628
- ISSN:
- 0009-3130
- Subject:
- Galium verum; Helicoverpa armigera; Scorpiones; chemical structure; glucosides; insecticidal properties; lignans; mortality; poisoning; scorpion venoms; spectral analysis; stomach; toxicity
- Abstract:
- ... A new lignan glucoside, galiveroside A (1), and seven known compounds (2–8), were isolated from Galium verum L. The structure of 1 was elucidated on the basis of extensive spectroscopic analyses. Compound 1, at the concentration of 5 mg/mL, showed insecticide activity to 3 age cotton bollworm with a mortality of 16.3% through stomach poisoning. When combined with a recombinant scorpion toxin rLqh ...
- DOI:
- 10.1007/s10600-017-2075-3
- https://doi.org/10.1007/s10600-017-2075-3
- Author:
- Jian-Hua Shao; Xue-Wei Zhang; Zi-Ling Dong; Si-Hui Li; Ben-Jie Miao; Ke-Zhi Cheng
- Source:
- Chemistry of natural compounds 2017 v.53 no.6 pp. 1025-1027
- ISSN:
- 0009-3130
- Subject:
- Cyclea; chemical structure; glucosides; lignans; spectral analysis
- Abstract:
- ... A new lignan glucoside 1, along with two known lignans (2, 3), was isolated from Cyclea racemosa Oliv. Its structure was elucidated as (+)-7′-methoxylariciresinol 4-O-β-D-glucopyranoside on the basis of extensive spectroscopic analyses. ...
- DOI:
- 10.1007/s10600-017-2193-y
- https://doi.org/10.1007/s10600-017-2193-y
- Author:
- Jing Liu; Dan Wang; Li He; Qi Mao; Xiaofang Hu
- Source:
- Phytochemistry letters 2017 v.22 pp. 247-250
- ISSN:
- 1874-3900
- Subject:
- Achillea millefolium; lignans; luteolin; methanol; nuclear magnetic resonance spectroscopy; spectral analysis; terpenoids
- Abstract:
- ... A phytochemical investigation from methanol extract of Achillea millefolium, (Asteraceae) resulted in the isolation of one new lignan, (+)-lyoniresinol 4-O-α-l −arabinofuranoside (1) and one new terpenoid, achiterpenoside A (2), together with four other known compounds, named as Achillinin A (3), (+)-lyoniresinol (4), luteolin (5), camazulene (6). The structures of 1 and 2 were elucidated based on ...
- DOI:
- 10.1016/j.phytol.2017.10.009
- https://doi.org/10.1016/j.phytol.2017.10.009
- Author:
- Xiao Feng; Guozhu Su; Yunyun Ye; Ruifei Zhang; Xinyao Yang; Bingzhao Du; Bing Peng; Pengfei Tu; Xingyun Chai
- Source:
- Natural product research 2017 v.31 no.13 pp. 1555-1560
- ISSN:
- 1478-6427
- Subject:
- Syringa; anti-inflammatory activity; bark; lignans; nuclear magnetic resonance spectroscopy; spectral analysis; traditional medicine
- Abstract:
- ... Two new lignans, alashinols F and G (1 and 2), together with two known analogues (−)-secoisolariciresinol (3) and meso -secoisolariciresinol (4) were isolated from the stem bark of Syringa pinnatifolia , a Mongolian folk medicine with anti-myocardial ischaemic effects. Their structures were elucidated on basis of spectroscopic data analyses, including MS and 1D and 2D NMR, and their absolute confi ...
- DOI:
- 10.1080/14786419.2017.1283500
- https://doi.org/10.1080/14786419.2017.1283500
- Author:
- Can Li; Hongxin Liu; Liyun Zhao; Weimin Zhang; Shengxiang Qiu; Xiaoyun Yang; Haibo Tan
- Source:
- Fitoterapia 2017 v.120 pp. 171-176
- ISSN:
- 0367-326X
- Subject:
- Melaleuca; aldehydes; antibiotic resistance; antimicrobial properties; biochemical pathways; biomimetics; leaves; lignans; methicillin; methicillin-resistant Staphylococcus aureus; odors; spectral analysis
- Abstract:
- ... Phytochemical study on the leaves of Melaleuca bracteata resulted in the isolation of ten compounds including three new neolignans, named melaleucins A–C (1–3). Among them, melaleucin B shares a rarely occurring nor-neolignan skeleton, and both melaleucins B and C bear a novel aldehyde moiety, which might also be response for the delicate fragrance of M. bracteata. Their structures were extensivel ...
- DOI:
- 10.1016/j.fitote.2017.06.015
- https://doi.org/10.1016/j.fitote.2017.06.015
- Author:
- Dan-Qi Li; Di Wang; Le Zhou; Ling-Zhi Li; Qing-Bo Liu; Ying-Ying Wu; Jing-Yu Yang; Shao-Jiang Song; Chun-Fu Wu
- Source:
- Journal of Asian natural products research 2017 v.19 no.5 pp. 519-527
- ISSN:
- 1477-2213
- Subject:
- 2,2-diphenyl-1-picrylhydrazyl; Bupleurum chinense; antioxidant activity; bioactive compounds; cytotoxicity; ethanol; fluorouracil; free radical scavengers; glucosides; inhibitory concentration 50; lignans; neoplasm cells; nuclear magnetic resonance spectroscopy; roots; spectral analysis
- Abstract:
- ... In the search for biologically active compounds from the roots of Bupleurum chinense D C., phytochemical investigation of its ethanol extract led to the isolation and identification of a new 8- O -4′ neolignan glucoside, saikolignanoside A (1), along with eight known lignans (2–9). Their structures were determined on the basis of IR, UV, HRESIMS, and NMR spectroscopic analyses. The antioxidant and ...
- DOI:
- 10.1080/10286020.2016.1234456
- https://doi.org/10.1080/10286020.2016.1234456
- Author:
- Gustav Komlaga; Grégory Genta-Jouve; Sandrine Cojean; Rita A. Dickson; Merlin L.K. Mensah; Philippe M. Loiseau; Pierre Champy; Mehdi A. Beniddir
- Source:
- Tetrahedron letters 2017 pp. -
- ISSN:
- 0040-4039
- Subject:
- Phyllanthus fraternus; Plasmodium falciparum; Securinega; alkaloids; antimalarials; antiparasitic properties; chemical reactions; chemical structure; inhibitory concentration 50; lignans; nuclear magnetic resonance spectroscopy; spectral analysis
- Abstract:
- ... The chemical investigation of the antimalarial plant Phyllanthus fraternus G. L. Webster (Phyllanthaceae) resulted in the discovery of the Securinega alkaloid (+)-allonorsecurinine (1), previously reported as a synthetic compound, together with the known ent-norsecurinine (2), nirurine (3), bubbialine (4), epibubbialine (5) and the lignan phyllanthin (6). The structure and absolute configuration o ...
- DOI:
- 10.1016/j.tetlet.2017.08.045
- https://doi.org/10.1016/j.tetlet.2017.08.045
- Author:
- Gao En; Zhou Zheng-Qun; Zou Jian; Yu Yang; Feng Xiao-Lin; Chen Guo-Dong; He Rong-Rong; Yao Xin-Sheng; Gao Hao
- Source:
- Journal of natural products 2017 v.80 no.11 pp. 2923-2929
- ISSN:
- 1520-6025
- Subject:
- 2,2-diphenyl-1-picrylhydrazyl; Acorus gramineus; acarbose; acetylcholinesterase; alpha-glucosidase; antioxidant activity; antioxidants; benzene; drugs; enantiomers; enzyme inhibition; high performance liquid chromatography; inhibitory concentration 50; lignans; phenylpropanoids; rhizomes; spectral analysis
- Abstract:
- ... Eight new (1a/1b, 2a, 3a, 4a/4b, and 5a/5b) and seven known (2b, 3b, and 6–10) asarone-derived phenylpropanoids, a known asarone-derived lignan (12), and four known lignan analogues (11 and 13–15) were isolated from the rhizome of Acorus tatarinowii Schott. The structures were elucidated via comprehensive spectroscopic analyses, modified Mosher’s method, and quantum chemical calculations. Compound ...
- DOI:
- 10.1021/acs.jnatprod.7b00457
- https://doi.org/10.1021/acs.jnatprod.7b00457
- Author:
- Tie Liu; Qian Liang; Xin-Min Zhang; Gen-Qian Li; Bo Xu; Wen-Hui Xu
- Source:
- Biochemical systematics and ecology 2017 v.75 pp. 27-30
- ISSN:
- 0305-1978
- Subject:
- Piper; alkaloids; chemical composition; chemotaxonomy; diterpenoids; lignans; monoterpenoids; nuclear magnetic resonance spectroscopy; spectral analysis
- Abstract:
- ... The chemical investigation of whole plants Piper boehmeriifolium (Miq.) Wall. ex C. DC. led to the isolation of 22 compounds, including two lignans (1–2), sixteen amide alkaloids (3–18), one diterpene (19), two monoterpenes (20–21), and one phenylpropanoid (22). Their structures were elucidated by extensive spectroscopic analyses including NMR, MS, and by comparison with the literature. Compounds ...
- DOI:
- 10.1016/j.bse.2017.11.003
- https://doi.org/10.1016/j.bse.2017.11.003
- Author:
- Clécio S. Ramos; Harrald V. Linnert; Marcilio M. de Moraes; João H. do Amaral; Lydia F. Yamaguchi; Massuo J. Kato
- Source:
- RSC advances 2017 v.7 no.74 pp. 46932-46937
- ISSN:
- 2046-2069
- Subject:
- Piper; density functional theory; hydrogen bonding; isomers; leaves; lignans; nuclear magnetic resonance spectroscopy; spectral analysis; tetrahydrofuran
- Abstract:
- ... The study of variability of the tetrahydrofuran lignan (−)-grandisin in leaves of Piper solmsianum (Piperaceae) revealed two unknown compounds, that were isolated and determined to be the all-cis tetrahydrofuran lignans 1a [rel-(7R,8S,7′S,8′R)-3,4,5,3′,4′,5′-hexamethoxy-7,7′-epoxylignan] and 1b [rel-(7R,8S,7′S,8R′)-3′,4′-methylenedioxy-3,4,5,5′-tetramethoxy-7,7′-epoxylignan]. Their structures were ...
- DOI:
- 10.1039/c7ra09262h
- https://doi.org/10.1039/c7ra09262h
- Author:
- Xinhua Ma; Jie Yang; Christopher L. Brown; Chao Wang; Shihao Deng; Ruifang Ke; Shicheng Xu; Mi Huang; Xinzhou Yang; Yunjiang Feng
- Source:
- RSC advances 2017 v.7 no.83 pp. 52970-52976
- ISSN:
- 2046-2069
- Subject:
- Daphniphyllum; Oriental traditional medicine; apoptosis; benzaldehyde; caspase-3; caspase-9; cell growth; cell lines; circular dichroism spectroscopy; cytotoxicity; dose response; humans; lignans; mitochondria; neoplasm cells; neoplasms; nuclear magnetic resonance spectroscopy; seeds; spectral analysis
- Abstract:
- ... Four new neolignans, (E)-3-(hydroxymethyl)-2-(4-hydroxyphenyl)-5-(prop-1-en-1-yl)benzofuran-6-ol (1), methyl (E)-6-hydroxy-2-(4-hydroxyphenyl)-5-(prop-1-en-1-yl)benzofuran-3-carboxylate (2), (R)-4-hydroxy-3-(1-(4-hydroxyphenyl)propan-2-yl)benzaldehyde (3) and methyl (E,R)-3-(4-hydroxy-3-(1-(4-hydroxyphenyl)propan-2-yl)phenyl)acrylate (4) were isolated from the seeds of Daphniphyllum macropodum Miq ...
- DOI:
- 10.1039/c7ra09569d
- https://doi.org/10.1039/c7ra09569d
- Author:
- Ban-Ban Li; Jia-Lin Li; Na Li; Shi-Zhou Qi; Hyun-Sun Lee; Le Zhang; Shan-Shan Xing; Zhen-Dong Tuo; Long Cui
- Source:
- Archives of pharmacal research 2017 v.40 no.11 pp. 1271-1277
- ISSN:
- 0253-6269
- Subject:
- Eleutherococcus senticosus; diacylglycerol acyltransferase; inhibitory concentration 50; lignans; spectral analysis; stems
- Abstract:
- ... Two new furofuran lignans were isolated from the stems of Acanthopanax senticosus, along with seven known compounds. Their structures were all determined by spectroscopic analyses and chemical methods. All the isolates were evaluated for in vitro inhibitory activity against DGAT1 and DGAT2. Compounds 1 and 2 were found to exhibit selective inhibitory activity on DGAT1 with IC₅₀ values 89.5 ± 1.5 a ...
- DOI:
- 10.1007/s12272-016-0842-5
- https://doi.org/10.1007/s12272-016-0842-5
- Author:
- Shou-Zhen Du; Zhi-Chong Wang; Ying Liu; Rui Zhan; Ye-Gao Chen
- Source:
- Phytochemistry letters 2017 v.19 pp. 98-100
- ISSN:
- 1874-3900
- Subject:
- acetone; branches; cytotoxicity; lignans; neoplasms; spectral analysis
- Abstract:
- ... Two new diarylpropanes (1–2), four known compounds, and a new artifact, were isolated from 70% aqueous acetone extract of the twigs of Horsfieldia tetratepala. Their structures were elucidated by spectroscopic analysis. Cytotoxicity evaluation against five cancer cell lines showed that none of these compounds was cytotoxic. ...
- DOI:
- 10.1016/j.phytol.2016.12.018
- https://doi.org/10.1016/j.phytol.2016.12.018
- Author:
- Le Zhou; Li-Li Lou; Wei Wang; Bin Lin; Jun-Ning Chen; Xiao-Bo Wang; Xiao-Xiao Huang; Shao-Jiang Song
- Source:
- Journal of functional foods 2017 v.37 pp. 322-329
- ISSN:
- 1756-4646
- Subject:
- Alzheimer disease; Rubus idaeus; chemical composition; chemical structure; functional foods; lignans; neuroprotective effect; spectral analysis; stereochemistry
- Abstract:
- ... Red raspberry (Rubus idaeus L.) is an edible fruit-producing species belonging to the Rosaceae family. In our search for potential agents for treating Alzheimer’s disease in this functional food, we decided to investigate the chemical constituents of red raspberry. Four pairs of enantiomeric 8-O-4′-type neolignans (1a/1b–4a/4b), including three new compounds (1a/1b and 2a), were identified from th ...
- DOI:
- 10.1016/j.jff.2017.08.007
- https://doi.org/10.1016/j.jff.2017.08.007
- Author:
- Abdulmagid Alabdul Magid; Anaëlle Abdellah; Virginie Pecher; Laure Pasquier; Dominique Harakat; Laurence Voutquenne-Nazabadioko
- Source:
- Phytochemistry letters 2017 v.21 pp. 84-89
- ISSN:
- 1874-3900
- Subject:
- 2,2-diphenyl-1-picrylhydrazyl; Opiliaceae; antioxidant activity; flavonols; glycosides; inhibitory concentration 50; leaves; lignans; mushrooms; spectral analysis
- Abstract:
- ... Two previously undescribed flavonol tetraglycosides, isorhamnetin-3-O-α-l-rhamnopyranosyl-(1→6)-β-d-galactopyranosyl-(1→4)-α-l-rhamnopyranosyl-(1→6)-β-d-glucopyranoside (1) and isorhamnetin-3-O-α-l-rhamnopyranosyl-(1→6)-β-d-galactopyranosyl-(1→4)-α-l-rhamnopyranosyl-(1→6)-β-d-galactopyranoside (2), along with nine known compounds including seven flavonoids and two lignans, were isolated from the l ...
- DOI:
- 10.1016/j.phytol.2017.05.023
- https://doi.org/10.1016/j.phytol.2017.05.023
- Author:
- Yue-Ting Li; Man-Man Li; Jing Sun; Zhi-Xiang Zhu; Yue-Lin Song; Dao-Ran Pang; Jiao Zheng; Yun-Fang Zhao; Peng-Fei Tu; Jun Li
- Source:
- Natural product research 2017 v.31 no.8 pp. 918-924
- ISSN:
- 1478-6427
- Subject:
- Vitex negundo; glucosides; inhibitory concentration 50; leaves; lignans; nitric oxide; spectral analysis; spectroscopy
- Abstract:
- ... Two new furofuran lignan glucosides, cannabilignin (1) and isocannabilignin (2), together with four known compounds (3 – 6), were isolated from the leaves of Vitex negundo var. cannabifolia . The structures of the isolates were elucidated by analysis of spectroscopic data. Compound 3 exhibited weak inhibition of nitric oxide production in lipopolysaccharide-stimulated BV-2 microglial cells with IC ...
- DOI:
- 10.1080/14786419.2016.1255887
- https://doi.org/10.1080/14786419.2016.1255887
- Author:
- Guo-Wei Wang; Li-Qing Deng; You-Ping Luo; Zhi-Hua Liao; Min Chen
- Source:
- Natural product research 2017 v.31 no.16 pp. 1855-1860
- ISSN:
- 1478-6427
- Subject:
- Schisandra; hepatoprotective effect; lignans; nuclear magnetic resonance spectroscopy; spectral analysis; stems; survival rate; triterpenoids
- Abstract:
- ... One new triterpenoid (1) and 13 known compounds (2–14) were isolated from Schisandra pubescens stems. The structure of the new compound was established on the basis of 1D/2D NMR and HRESIMS spectroscopic analyses. The isolated compounds were evaluated for their hepatoprotective activities against D-GalN-induced cell injury in QSG7701 cells. Compounds 1, 13 and 14 at 10 μM showed hepatoprotective a ...
- DOI:
- 10.1080/14786419.2016.1261348
- https://doi.org/10.1080/14786419.2016.1261348
- Author:
- Jicheng Shu; Fang Liang; Genhua Zhu; Xing Liu; Jiangli Yu; Huilian Huang
- Source:
- Phytochemistry letters 2017 v.20 pp. 1-8
- ISSN:
- 1874-3900
- Subject:
- Smilax; cytotoxicity; electrospray ionization mass spectrometry; glycosides; humans; inhibitory concentration 50; lignans; neoplasm cells; nuclear magnetic resonance spectroscopy; rhizomes; spectral analysis
- Abstract:
- ... Phytochemical investigation of the rhizomes of Smilax trinervula led to isolation and structure elucidation of eight lignan glycosides, including five new lignans, namely, (7S, 8R, 8′R)-4, 4′, 9-trihydroxy-3, 3′, 5, 5′-tetramethoxy-7, 9′-epoxylignan-7′-one 4′-O-β-d-glucopyranoside (1), (7S, 8R, 8′R)-4, 4′, 9-trihydroxy-3, 3′, 5, 5′-tetramethoxy-7, 9′-epoxylignan-7′-one 4-O-β-d- glucopyranoside (2) ...
- DOI:
- 10.1016/j.phytol.2017.03.002
- https://doi.org/10.1016/j.phytol.2017.03.002
- Author:
- Xue-Yan YANG; Yi-Fan ZHANG; Li-Jia LIU; Yi WANG; Ming-Ying SHANG; Feng XU; Guang-Xue LIU; Shao-Qing CAI
- Source:
- Chinese journal of natural medicines 2017 v.15 no.12 pp. 938-943
- ISSN:
- 1875-5364
- Subject:
- Linaceae; Oriental traditional medicine; aerial parts; anti-inflammatory activity; cell lines; cytotoxicity; diterpenoids; ethanol; ethyl acetate; inflammation; inhibitory concentration 50; lignans; macrophages; mice; models; nitric oxide; spectral analysis
- Abstract:
- ... A new lignan, tirpitzin A (17) together with 20 known compounds (1–16, and 18–21) were isolated from the ethyl acetate soluble fraction of ethanol extract of the aerial parts of Tirpitzia ovoidea. The structure of new compound was elucidated by means of spectroscopic analysis. Of the known compounds, 7–21 were isolated from Linaceae family for the first time. The pharmacological activity of the cr ...
- DOI:
- 10.1016/S1875-5364(18)30010-4
- https://doi.org/10.1016/S1875-5364(18)30010-4
- Author:
- Ming Bai; Guo-Dong Yao; Si-Fan Liu; Di Wang; Qing-Bo Liu; Xiao-Xiao Huang; Shao-Jiang Song
- Source:
- Journal of functional foods 2017 v.28 pp. 106-113
- ISSN:
- 1756-4646
- Subject:
- Alzheimer disease; active ingredients; antioxidants; chemical structure; ethanol; functional foods; green leafy vegetables; lignans; molecular models; neuroprotective effect; salads; soups; spectral analysis; tetrahydrofuran; China; Japan; Korean Peninsula; North America
- Abstract:
- ... Patrinina villosa Juss. is a delicious wild vegetable, which is widely distributed in China, Korea, Japan and North America. P. villosa, which smells fresh and is highly nutritious, can be made into a salad, used as greens and as a porridge and soup. Phytochemical investigation of the 70% EtOH extract showed the presence of two dibenzylbutyrolactone lignans (1–2), named Patrinians (A-B), along wit ...
- DOI:
- 10.1016/j.jff.2016.10.024
- https://doi.org/10.1016/j.jff.2016.10.024
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