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- Wu, Mingjiang, et al. Show all 6 Authors
- Fish & shellfish immunology 2017 v.70 pp. 1-12
- Acipenser sinensis; T-lymphocytes; adaptive immunity; bacterial vaccines; complementary DNA; dendritic cells; evolution; immune response; interleukin-6; intestines; kidneys; liver; major histocompatibility complex; messenger RNA; mice; mutation; pathogens; spleen; sturgeon; traffic; transcription factor NF-kappa B; tumor necrosis factor-alpha
- ... The major histocompatibility complex class II (MHC II) molecules play a vital role in adaptive immune response through presenting antigenic peptides to CD4+ T lymphocytes. To accomplish this physiologic function, the MHC class II-associated invariant chain interacts with the MHC II α/β subunits and promotes their correct assembly and efficient traffic. Here, we isolated the cDNAs of MHC II α, β an ...