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- Zhao, Dong-Hao; Wang, Xu-Feng; Wang, Qiang; Li, Liu-Dong
- BMC veterinary research 2017 v.13 no.1 pp. 226
- bioavailability, etc ; Cygnus; Escherichia coli; Monte Carlo method; drug resistance; intravenous injection; pharmacodynamics; pharmacokinetics; risk; Show all 9 Subjects
- ... BACKGROUND: The objective of this study is to investigate pharmacokinetics and dose regimens of cefquinome in black swans following intravenous (IV) and intramuscular (IM) administration at a single dose of 2 mg/kg. The MICs of cefquinome against 49 Escherichia coli isolates from black swans were determined. Monte Carlo simulation was applied to conduct the dose regimen assessment and optimization ...
- PubMed Central: