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1. Punica granatum peel extracts: HPLC fractionation and LC MS analysis to quest compounds having activity against multidrug resistant bacteria

Author:
Khan, Ilyas; Rahman, Hazir; Abd El-Salam, NasserM.; Tawab, Abdul; Hussain, Anwar; Khan, TajAli; Khan, UsmanAli; Qasim, Muhammad; Adnan, Muhammad; Azizullah, Azizullah; Murad, Waheed; Jalal, Abdullah; Muhammad, Noor; Ullah, Riaz
Source:
BMC complementary and alternative medicine 2017 v.17 no.1 pp. 247
ISSN:
1472-6882
Subject:
Acinetobacter baumannii; Escherichia coli; Pseudomonas aeruginosa; Punica granatum; Staphylococcus aureus; alternative medicine; animal pathogens; antibacterial properties; bacteria; bioactive compounds; chloroform; coumaric acids; ethanol; fractionation; herbal medicines; hexane; high performance liquid chromatography; medicinal plants; medicinal properties; multiple drug resistance
Abstract:
... BACKGROUND: Medicinal plants are rich source of traditional herbal medicine around the globe. Most of the plant’s therapeutic properties are due to the presence of secondary bioactive compounds. METHODS: The present study analyzed the High Pressure Liquid Chromatography (HPLC) fractions of Puncia granatum (peel) extracts (aqueous, chloroform, ethanol and hexane) against multidrug resistant bacteri ...
DOI:
10.1186/s12906-017-1766-4
PubMed:
28468660
PubMed Central:
PMC5415797

2. Similar, but different: structurally related azelaic acid and hexanoic acid trigger differential metabolomic and transcriptomic responses in tobacco cells

Author:
Djami-Tchatchou, Arnaud T.; Ncube, Efficient N.; Steenkamp, Paul A.; Dubery, Ian A.
Source:
BMC plant biology 2017 v.17 no.1 pp. 227
ISSN:
1471-2229
Subject:
Nicotiana tabacum; alternative crops; biomarkers; chlorogenic acid; coumaric acids; elicitors; ethylene; gene expression; gene expression regulation; genes; glycosides; guanosinetriphosphatase; hexanoic acid; hydroxycinnamoyltransferase; jasmonic acid; mechanism of action; metabolism; metabolome; metabolomics; pathogenesis-related proteins; phenylalanine ammonia-lyase; plant protection; quantitative polymerase chain reaction; salicylic acid; signal transduction; systemic acquired resistance; thioredoxins; tobacco; transcriptomics
Abstract:
... BACKGROUND: Plants respond to various stress stimuli by activating an enhanced broad-spectrum defensive ability. The development of novel resistance inducers represents an attractive, alternative crop protection strategy. In this regard, hexanoic acid (Hxa, a chemical elicitor) and azelaic acid (Aza, a natural signaling compound) have been proposed as inducers of plant defense, by means of a primi ...
DOI:
10.1186/s12870-017-1157-5
PubMed:
29187153
PubMed Central:
PMC5706331

3. Effect of Green and Brown Propolis Extracts on the Expression Levels of microRNAs, mRNAs and Proteins, Related to Oxidative Stress and Inflammation

Author:
Zaccaria, Vincenzo; Curti, Valeria; Di Lorenzo, Arianna; Baldi, Alessandra; Maccario, Cristina; Sommatis, Sabrina; Mocchi, Roberto; Daglia, Maria
Source:
Nutrients 2017 v.9 no.10
ISSN:
2072-6643
Subject:
antioxidant activity; antioxidants; coumaric acids; flavonoids; glutathione peroxidase; human cell lines; inflammation; keratinocytes; mechanism of action; messenger RNA; metabolites; microRNA; oxidative stress; polyphenols; propolis; protein content; proteins; tumor necrosis factor-alpha
Abstract:
... A large body of evidence highlights that propolis exerts many biological functions that can be ascribed to its antioxidant and anti-inflammatory components, including different polyphenol classes. Nevertheless, the molecular mechanisms are yet unknown. The aim of this study is to investigate the mechanisms at the basis of propolis anti-inflammatory and antioxidant activities. The effects of two br ...
DOI:
10.3390/nu9101090
PubMed:
28974022
PubMed Central:
PMC5691707

4. Profiling hydroxycinnamic acid glycosides, iridoid glycosides, and phenylethanoid glycosides in baobab fruit pulp (Adansonia digitata)

Author:
Li, Xing-Nuo; Sun, Jianghao; Shi, Haiming; Yu, Lucy (Liangli); Ridge, Clark D.; Mazzola, Eugene P.; Okunji, Christopher; Iwu, Maurice M.; Michel, Tchimene Kenne; Chen, Pei
Source:
Food research international 2017 v.99 pp. 755-761
ISSN:
0963-9969
Subject:
Adansonia digitata; chemical composition; coumaric acids; fruit pulp; iridoid glycosides; mass spectrometry; nuclear magnetic resonance spectroscopy; spectral analysis; trees; ultra-performance liquid chromatography; Africa
Abstract:
... The baobab (Adansonia digitata L.) is a magnificent tree revered throughout Africa and is becoming recognized for its high nutritional and medicinal values. Despite numerous reports on the pharmacological potential, little is known about its chemical compositions. In this study, four hydroxycinnamic acid glycosides (1–4), six iridoid glycosides (5–10), and three phenylethanoid glycosides (11–13) w ...
DOI:
10.1016/j.foodres.2017.06.025
PubMed:
28784541
PubMed Central:
PMC5555379
CHORUS:
10.1016/j.foodres.2017.06.025

5. Dietary polyphenols are inversely associated with metabolic syndrome in Polish adults of the HAPIEE study

Author:
Grosso, Giuseppe; Stepaniak, Urszula; Micek, Agnieszka; Stefler, Denes; Bobak, Martin; Pająk, Andrzej
Source:
European journal of nutrition 2017 v.56 no.4 pp. 1409-1420
ISSN:
1436-6207
Subject:
polyphenols; energy intake; stilbenes; coumaric acids; odds ratio; waist circumference; food frequency questionnaires; flavanols; blood pressure; adults; women; lipoproteins; females; databases; metabolic syndrome; men; cohort studies; blood glucose; triacylglycerols; psychosocial factors; lignans; diabetes; body mass index; regression analysis; confidence interval; cholesterol; Eastern European region; Poland
Abstract:
... PURPOSE: The aim of this study was to evaluate the association between total and individual classes and subclasses of dietary polyphenol intake and prevalence of metabolic syndrome (MetS) in the Polish arm of the Health, Alcohol and Psychosocial factors In Eastern Europe cohort study. METHODS: A cross-sectional population-based survey including 8821 adults (51.4 % female) was conducted in Kraków, ...
DOI:
10.1007/s00394-016-1187-z
PubMed:
26913852
PubMed Central:
PMC5486632

6. Distribution of phenolic compounds and antioxidant capacity in apples tissues during ripening

Author:
Alberti, Aline; Zielinski, Acácio Antonio Ferreira; Couto, Marcelo; Judacewski, Priscila; Mafra, Luciana Igarashi; Nogueira, Alessandro
Source:
Journal of food science and technology 2017 v.54 no.6 pp. 1511-1518
ISSN:
0022-1155
Subject:
2,2-diphenyl-1-picrylhydrazyl; anthocyanins; antioxidant activity; apples; coumaric acids; endocarp; flavanols; flavonols; mesocarp; ripening; tissues
Abstract:
... The effect of variety and ripening stage on the distribution of phenolic compounds and in vitro antioxidant capacity of Gala, Fuji Suprema and Eva apples were evaluated. Hydroxycinnamic acids, flavonoids, flavanols, flavonols, dihydrochalcones and antioxidant activity (FRAP and DPPH) were assessed in the epicarp, mesocarp and endocarp of three varieties at three ripening stages (unripe, ripe and s ...
DOI:
10.1007/s13197-017-2582-z
PubMed:
28559610
PubMed Central:
PMC5430183

7. Feruloyl dopamine-O-hexosides are efficient marker compounds as orthogonal validation for authentication of black cohosh (Actaea racemosa)—an UHPLC-HRAM-MS chemometrics study

Author:
Geng, Ping; Harnly, James M.; Sun, Jianghao; Zhang, Mengliang; Chen, Pei
Source:
Analytical and bioanalytical chemistry 2017 v.409 no.10 pp. 2591-2600
ISSN:
1618-2642
Subject:
Actaea racemosa; adulterated products; chemical composition; chemometrics; coumaric acids; data collection; discriminant analysis; glycosides; isomers; liquid chromatography; mass spectrometry; models; plant biochemistry; principal component analysis; tyramine
Abstract:
... Due to the complexity and variation of the chemical constituents in authentic black cohosh (Actaea racemosa) and its potential adulterant species, an accurate and feasible method for black cohosh authentication is not easy. A high-resolution accurate mass (HRAM) LC-MS fingerprinting method combined with chemometric approach was employed to discover new marker compounds. Seven hydroxycinnamic acid ...
DOI:
10.1007/s00216-017-0205-1
PubMed:
28160032
PubMed Central:
PMC5360482

8. Identification and characterization of a fusarium head blight resistance gene TaACT in wheat QTL‐2DL

Author:
Kage, Udaykumar; Karre, Shailesh; Kushalappa, Ajjamada C.; McCartney, Curt
Source:
Plant biotechnology journal 2017 v.15 no.4 pp. 447-457
ISSN:
1467-7644
Subject:
Arabidopsis; Fusarium graminearum; Fusarium head blight; Triticum aestivum; agmatine; amides; barley; biochemical pathways; cell walls; chromosomes; coumaric acids; disease resistance; disease severity; gene silencing; metabolites; metabolomics; microbial biomass; mutants; phylogeny; quantitative trait loci; resistance genes; resistance mechanisms; sequence analysis; single nucleotide polymorphism; surveys; transferases; wheat
Abstract:
... Fusarium head blight (FHB) resistance in wheat is considered to be polygenic in nature. Cell wall fortification is one of the best resistance mechanisms in wheat against Fusarium graminearum which causes FHB. Metabolomics approach in our study led to the identification of a wide array of resistance‐related (RR) metabolites, among which hydroxycinnamic acid amides (HCAAs), such as coumaroylagmatine ...
DOI:
10.1111/pbi.12641
PubMed:
27663684
PubMed Central:
PMC5362683

9. Distribution of free, esterified, and insoluble bound forms of phenolics in tea seeds and their antioxidant activity

Author:
Kang, Ok-Ju
Source:
Food science and biotechnology 2017 v.26 no.1 pp. 121-127
ISSN:
1226-7708
Subject:
2,2-diphenyl-1-picrylhydrazyl; antioxidant activity; antioxidants; copper; coumaric acids; esterification; high performance liquid chromatography; in vitro studies; iron; seeds; tea
Abstract:
... In this study, phenolic compounds in their phenolic extract (PE), free phenolic (FP), esterified phenolic (EFP), and insoluble bound phenolic (ISBP) forms were extracted from tea seeds and quantified using HPLC to obtain information on the phenolics that are present in tea seeds along with their antioxidant activities. The total phenolic content of the ISBP fraction was higher than that of the FP ...
DOI:
10.1007/s10068-017-0016-3
PubMed:
30263518
PubMed Central:
PMC6049488

10. Effect of mixing different kinds of fruit juice with sour cherry puree on nutritional properties

Author:
Nowicka, Paulina; Wojdyło, Aneta; Teleszko, Mirosława
Source:
Journal of food science and technology 2017 v.54 no.1 pp. 114-129
ISSN:
0022-1155
Subject:
Prunus cerasus; anthocyanins; antioxidant activity; apples; ascorbic acid; color; correlation; coumaric acids; flavanols; flavonols; flowering; fruit puree; juices; liquid chromatography; mass spectrometry; mixing; nutritive value; pears; pectins; procyanidins; quinces; synergism; titratable acidity; total soluble solids; viscosity
Abstract:
... The main objective of this study was to investigate the effect of mixing sour cherry puree with apple, pear, quince and flowering quince juices on characteristics of 17 different products (12 smoothies and 5 semi-products). Compounds (phenolic compounds, vitamin C, sugar, pectin), antioxidant activity (ORAC, ABTS, FRAP), and physicochemical parameters (titratable acidity, soluble solids, viscosity ...
DOI:
10.1007/s13197-016-2442-2
PubMed:
28242910
PubMed Central:
PMC5305708