Jump to Main Content
- Dar, Tanveer A., et al. Show all 5 Authors
- Biochemistry 2017 v.56 no.51 pp. 6662-6676
- carbon; cytochrome c; guanidines; models; mutation; nitrogen; nuclear magnetic resonance spectroscopy; pH; protein secondary structure; stable isotopes; yeasts
- ... There is considerable evidence that long-range interactions stabilize residual protein structure under denaturing conditions. However, evaluation of the effect of a specific contact on structure in the denatured state has been difficult. Iso-1-cytochrome c variants with a Lys54 → His mutation form a particularly stable His–heme loop in the denatured state, suggestive of loop-induced residual struc ...
- PubMed Central: